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Protein
Submitted name:

RalBP1-associated Eps domain-containing protein 1

Gene

REPS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi317 – 328PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
RalBP1-associated Eps domain-containing protein 1Imported
Gene namesi
Name:REPS1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000135597.18
HGNCiHGNC:15578 REPS1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000135597

PTM / Processingi

Proteomic databases

MaxQBiH0YDT0
PeptideAtlasiH0YDT0
PRIDEiH0YDT0

Expressioni

Gene expression databases

BgeeiENSG00000135597 Expressed in 195 organ(s), highest expression level in right uterine tube
ExpressionAtlasiH0YDT0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YDT0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 99EHInterPro annotationAdd BLAST99
Domaini271 – 355EHInterPro annotationAdd BLAST85
Domaini304 – 339EF-handInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili713 – 744Sequence analysisAdd BLAST32

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1955 Eukaryota
ENOG410ZSYS LUCA
GeneTreeiENSGT00760000118985

Family and domain databases

CDDicd00052 EH, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR000261 EH_dom
IPR026814 Reps1
PANTHERiPTHR11216:SF63 PTHR11216:SF63, 2 hits
PfamiView protein in Pfam
PF12763 EF-hand_4, 1 hit
SMARTiView protein in SMART
SM00027 EH, 1 hit
SUPFAMiSSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 1 hit
PS50031 EH, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

H0YDT0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
SDLFSYCDIE STKKVVVNGR VLELFRAAQL PNDVVLQIME LCGATRLGYF
60 70 80 90 100
GRSQFYIALK LVAVAQSGFP LRVESINTVK DLPLPRFVAS KNEQESRHAA
110 120 130 140 150
SYSSDSENQG SYSGVIPPPP GRGQVKKGSV SHDTVQPRTS ADAQEPASPV
160 170 180 190 200
VSPQQSPPTS PHTWRKHSRH PSGGNSERPL AGPGPFWSPF GEAQSGSSAG
210 220 230 240 250
DAVWSGHSPP PPQENWVSFA DTPPTSTLLT MHPASVQDQT TVRTVASATT
260 270 280 290 300
AIEIRRQSSS YDDPWKITDE QRQYYVNQFK TIQPDLNGFI PGSAAKEFFT
310 320 330 340 350
KSKLPILELS HIWELSDFDK DGALTLDEFC AAFHLVVARK NGYDLPEKLP
360 370 380 390 400
ESLMPKLIDL EDSADVGDQP GEVGYSGSPA EAPPSKSPSM PSLNQTWPEL
410 420 430 440 450
NQSSEDTAIV HPVPIRMTPS KIHMQEMELK RTGSDHTNPT SPLLVKPSDL
460 470 480 490 500
LEENKINSSV KFASGNTVDG YSSSDSFTSD PEQIGSNVTR QRSHSGTSPD
510 520 530 540 550
NTAPPPPPPR PQPSHSRSSS LDMNRTFTVT TGQQQAGVVA HPPAVPPRPQ
560 570 580 590 600
PSQAPGPAVH RPVDADGLIT HTSTSPQQIP EQPNFADFSQ FEVFAASNVN
610 620 630 640 650
DEQDDEAEKH PEVLPAEKAS DPASSLRVAK TDSKTEEKTA ASAPANVSKG
660 670 680 690 700
TTPLAPPPKP VRRRLKSEDE LRPEVDEHTQ KTGVLAAVLA SQPSIPRSVG
710 720 730 740 750
KDKKAIQASI RRNKETNTVL ARLNSELQQQ LKDVLEERIS LEVQLEQLRP

FSHL
Length:754
Mass (Da):81,949
Last modified:February 22, 2012 - v1
Checksum:i8177393693DB97BA
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96D71REPS1_HUMAN
RalBP1-associated Eps domain-contai...
REPS1
796Annotation score:
E9PMG1E9PMG1_HUMAN
RalBP1-associated Eps domain-contai...
REPS1
737Annotation score:
H7C1V2H7C1V2_HUMAN
RalBP1-associated Eps domain-contai...
REPS1
147Annotation score:
H7C225H7C225_HUMAN
RalBP1-associated Eps domain-contai...
REPS1
102Annotation score:
F2Z3L2F2Z3L2_HUMAN
RalBP1-associated Eps domain-contai...
REPS1
220Annotation score:
H0YCF0H0YCF0_HUMAN
RalBP1-associated Eps domain-contai...
REPS1
121Annotation score:
H0YE73H0YE73_HUMAN
RalBP1-associated Eps domain-contai...
REPS1
146Annotation score:
H0YCR2H0YCR2_HUMAN
RalBP1-associated Eps domain-contai...
REPS1
152Annotation score:
H0YE89H0YE89_HUMAN
RalBP1-associated Eps domain-contai...
REPS1
61Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121834 Genomic DNA No translation available.
AL590308 Genomic DNA No translation available.
AL591033 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000529597; ENSP00000434251; ENSG00000135597
UCSCiuc063rvr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121834 Genomic DNA No translation available.
AL590308 Genomic DNA No translation available.
AL591033 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YDT0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0YDT0
PeptideAtlasiH0YDT0
PRIDEiH0YDT0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000529597; ENSP00000434251; ENSG00000135597
UCSCiuc063rvr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000135597.18
HGNCiHGNC:15578 REPS1
OpenTargetsiENSG00000135597
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1955 Eukaryota
ENOG410ZSYS LUCA
GeneTreeiENSGT00760000118985

Miscellaneous databases

ChiTaRSiREPS1 human

Gene expression databases

BgeeiENSG00000135597 Expressed in 195 organ(s), highest expression level in right uterine tube
ExpressionAtlasiH0YDT0 baseline and differential

Family and domain databases

CDDicd00052 EH, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR000261 EH_dom
IPR026814 Reps1
PANTHERiPTHR11216:SF63 PTHR11216:SF63, 2 hits
PfamiView protein in Pfam
PF12763 EF-hand_4, 1 hit
SMARTiView protein in SMART
SM00027 EH, 1 hit
SUPFAMiSSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 1 hit
PS50031 EH, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiH0YDT0_HUMAN
AccessioniPrimary (citable) accession number: H0YDT0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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