UniProtKB - H0YCJ5 (H0YCJ5_HUMAN)
Protein
Submitted name:
Baculoviral IAP repeat-containing protein 3
Gene
BIRC3
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- regulation of apoptotic process Source: InterPro
Keywordsi
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
SignaLinki | H0YCJ5 |
Names & Taxonomyi
Protein namesi | Submitted name: Baculoviral IAP repeat-containing protein 3Imported |
Gene namesi | Name:BIRC3Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:591, BIRC3 |
VEuPathDBi | HostDB:ENSG00000023445.13 |
PTM / Processingi
Proteomic databases
MaxQBi | H0YCJ5 |
PeptideAtlasi | H0YCJ5 |
PRIDEi | H0YCJ5 |
ProteomicsDBi | 37083 |
Expressioni
Gene expression databases
Bgeei | ENSG00000023445, Expressed in tonsil and 194 other tissues |
ExpressionAtlasi | H0YCJ5, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 64 – 154 | CARDInterPro annotationAdd BLAST | 91 | |
Domaini | 182 – 216 | RING-typeInterPro annotationAdd BLAST | 35 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 38 – 65 | Sequence analysisAdd BLAST | 28 |
Keywords - Domaini
Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000154175 |
HOGENOMi | CLU_1478290_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR001315, CARD IPR011029, DEATH-like_dom_sf IPR001841, Znf_RING |
Pfami | View protein in Pfam PF00619, CARD, 1 hit |
SMARTi | View protein in SMART SM00114, CARD, 1 hit SM00184, RING, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit |
PROSITEi | View protein in PROSITE PS50209, CARD, 1 hit PS50089, ZF_RING_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
H0YCJ5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMNTPVINAA VEMGFSRSLV KQTVQRKILA TGENYRLVND LVLDLLNAED
60 70 80 90 100
EIREEERERA TEEKESNDLL LIRKNRMALF QHLTCVIPIL DSLLTAGIIN
110 120 130 140 150
EQEHDVIKQK TQTSLQAREL IDTILVKGNI AATVFRNSLQ EAEAVLYEHL
160 170 180 190 200
FVQQDIKYIP TEDVSDLPVE EQLRRLQEER TCKVCMDKEV SIVFIPCGHL
210
VVCKDCAPSL RKCPIC
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ13489 | BIRC3_HUMAN | Baculoviral IAP repeat-containing p... | BIRC3 API2, MIHC, RNF49 | 604 | Annotation score: | ||
A0A669KBC7 | A0A669KBC7_HUMAN | Baculoviral IAP repeat-containing p... | BIRC3 | 645 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 216 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP000942 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000527309; ENSP00000431718; ENSG00000023445 |
UCSCi | uc058guy.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP000942 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | H0YCJ5 |
PeptideAtlasi | H0YCJ5 |
PRIDEi | H0YCJ5 |
ProteomicsDBi | 37083 |
Protocols and materials databases
Antibodypediai | 1035, 672 antibodies |
Genome annotation databases
Ensembli | ENST00000527309; ENSP00000431718; ENSG00000023445 |
UCSCi | uc058guy.1, human |
Organism-specific databases
HGNCi | HGNC:591, BIRC3 |
OpenTargetsi | ENSG00000023445 |
VEuPathDBi | HostDB:ENSG00000023445.13 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154175 |
HOGENOMi | CLU_1478290_0_0_1 |
Enzyme and pathway databases
SignaLinki | H0YCJ5 |
Miscellaneous databases
ChiTaRSi | BIRC3, human |
Gene expression databases
Bgeei | ENSG00000023445, Expressed in tonsil and 194 other tissues |
ExpressionAtlasi | H0YCJ5, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR001315, CARD IPR011029, DEATH-like_dom_sf IPR001841, Znf_RING |
Pfami | View protein in Pfam PF00619, CARD, 1 hit |
SMARTi | View protein in SMART SM00114, CARD, 1 hit SM00184, RING, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit |
PROSITEi | View protein in PROSITE PS50209, CARD, 1 hit PS50089, ZF_RING_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H0YCJ5_HUMAN | |
Accessioni | H0YCJ5Primary (citable) accession number: H0YCJ5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | June 17, 2020 | |
Last modified: | February 10, 2021 | |
This is version 54 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |