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Protein
Submitted name:

Eukaryotic translation initiation factor 4 gamma 2

Gene

EIF4G2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 4 gamma 2Imported
Gene namesi
Name:EIF4G2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000110321.15
HGNCiHGNC:3297 EIF4G2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000110321

PTM / Processingi

Proteomic databases

PeptideAtlasiH0YCF8
PRIDEiH0YCF8

Expressioni

Gene expression databases

BgeeiENSG00000110321 Expressed in 242 organ(s), highest expression level in visceral pleura
ExpressionAtlasiH0YCF8 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 128MIF4GInterPro annotationAdd BLAST51

Phylogenomic databases

eggNOGiENOG410IPIB Eukaryota
ENOG410ZIZB LUCA
GeneTreeiENSGT00530000063038

Family and domain databases

Gene3Di1.25.40.180, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR016021 MIF4-like_sf
IPR003890 MIF4G-like_typ-3
PfamiView protein in Pfam
PF02854 MIF4G, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 15 potential isoforms that are computationally mapped.Show allAlign All

H0YCF8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
VESAIAEGGA SRFSASSGGG GSRGAPQHYP KTAGNSEFLG KTPGQNAQKW
60 70 80 90 100
IPARSTRRDD NSAANNSANE KERHDAIFRK VRGILNKLTP EKFDKLCLEL
110 120
LNVGVESKLI LKGVILLIVD KALEEPKYS
Length:129
Mass (Da):13,891
Last modified:October 5, 2016 - v8
Checksum:iEC00FC8197964AB7
GO

Computationally mapped potential isoform sequencesi

There are 15 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P78344IF4G2_HUMAN
Eukaryotic translation initiation f...
EIF4G2 DAP5, OK/SW-cl.75
907Annotation score:
D3DQV9D3DQV9_HUMAN
Eukaryotic translation initiation f...
EIF4G2 hCG_1991788
907Annotation score:
H0Y3P2H0Y3P2_HUMAN
Eukaryotic translation initiation f...
EIF4G2
869Annotation score:
H0YCH5H0YCH5_HUMAN
Eukaryotic translation initiation f...
EIF4G2
444Annotation score:
E9PKF8E9PKF8_HUMAN
Eukaryotic translation initiation f...
EIF4G2
185Annotation score:
H0YEC5H0YEC5_HUMAN
Eukaryotic translation initiation f...
EIF4G2
244Annotation score:
H0YD77H0YD77_HUMAN
Eukaryotic translation initiation f...
EIF4G2
282Annotation score:
H0YE44H0YE44_HUMAN
Eukaryotic translation initiation f...
EIF4G2
88Annotation score:
H0YDC0H0YDC0_HUMAN
Eukaryotic translation initiation f...
EIF4G2
116Annotation score:
H0YE22H0YE22_HUMAN
Eukaryotic translation initiation f...
EIF4G2
234Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei129Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC116535 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000532570; ENSP00000431511; ENSG00000110321
UCSCiuc057zcd.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC116535 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH0YCF8
PRIDEiH0YCF8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000532570; ENSP00000431511; ENSG00000110321
UCSCiuc057zcd.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000110321.15
HGNCiHGNC:3297 EIF4G2
OpenTargetsiENSG00000110321
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IPIB Eukaryota
ENOG410ZIZB LUCA
GeneTreeiENSGT00530000063038

Miscellaneous databases

ChiTaRSiEIF4G2 human

Gene expression databases

BgeeiENSG00000110321 Expressed in 242 organ(s), highest expression level in visceral pleura
ExpressionAtlasiH0YCF8 baseline and differential

Family and domain databases

Gene3Di1.25.40.180, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR016021 MIF4-like_sf
IPR003890 MIF4G-like_typ-3
PfamiView protein in Pfam
PF02854 MIF4G, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YCF8_HUMAN
AccessioniPrimary (citable) accession number: H0YCF8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 49 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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