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Protein
Submitted name:

Ephrin type-A receptor 10

Gene

EPHA10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Ephrin type-A receptor 10Imported
Gene namesi
Name:EPHA10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000183317.16
HGNCiHGNC:19987 EPHA10

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei65 – 89HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000183317

PTM / Processingi

Proteomic databases

PeptideAtlasiH0YCC9
PRIDEiH0YCC9

Expressioni

Gene expression databases

BgeeiENSG00000183317 Expressed in 113 organ(s), highest expression level in sperm
ExpressionAtlasiH0YCC9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YCC9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 54Fibronectin type-IIIInterPro annotationAdd BLAST54
Domaini145 – 392Protein kinaseInterPro annotationAdd BLAST248

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0196 Eukaryota
COG0515 LUCA
GeneTreeiENSGT00760000118975

Family and domain databases

CDDicd00063 FN3, 1 hit
InterProiView protein in InterPro
IPR027936 Eph_TM
IPR003961 FN3_dom
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
PfamiView protein in Pfam
PF14575 EphA2_TM, 1 hit
PF07714 Pkinase_Tyr, 1 hit
PRINTSiPR00109 TYRKINASE
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

H0YCC9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
EQTYSMVKTG APTVTVTNLK PATRYVFQIR AASPGPSWEA QSFNPSIEVQ
60 70 80 90 100
TLGEAASGSR DQSPAIVVTV VTISALLVLG SVMSVLAIWR RPCSYGKGGG
110 120 130 140 150
DAHDEEELYF HFKVPTRRTF LDPQSCGDLL QAVHLFAKEL DAKSVTLERS
160 170 180 190 200
LGGGRFGELC CGCLQLPGRQ ELLVAVHMLR DSASDSQRLG FLAEALTLGQ
210 220 230 240 250
FDHSHIVRLE GVVTRGSTLM IVTEYMSHGA LDGFLRRHEG QLVAGQLMGL
260 270 280 290 300
LPGLASAMKY LSEMGYVHRG LAARHVLVSS DLVCKISGFG RGPRDRSEAV
310 320 330 340 350
YTTMSGRSPA LWAAPETLQF GHFSSASDVW SFGIIMWEVM AFGERPYWDM
360 370 380 390
SGQDVIKAVE DGFRLPPPRN CPNLLHRLML DCWQKDPGLP PH
Length:392
Mass (Da):42,890
Last modified:February 22, 2012 - v1
Checksum:iA25E69B12754DC07
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5JZY3EPHAA_HUMAN
Ephrin type-A receptor 10
EPHA10
1,008Annotation score:
J3KQG3J3KQG3_HUMAN
EPH receptor A10, isoform CRA_b
EPHA10 hCG_1820945
1,014Annotation score:
H0YD12H0YD12_HUMAN
Ephrin type-A receptor 10
EPHA10
218Annotation score:
F5GWI2F5GWI2_HUMAN
Ephrin type-A receptor 10
EPHA10
155Annotation score:
H0YER4H0YER4_HUMAN
Ephrin type-A receptor 10
EPHA10
217Annotation score:
H0YEP6H0YEP6_HUMAN
Ephrin type-A receptor 10
EPHA10
92Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104336 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000534097; ENSP00000431389; ENSG00000183317
UCSCiuc057exi.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104336 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YCC9
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH0YCC9
PRIDEiH0YCC9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000534097; ENSP00000431389; ENSG00000183317
UCSCiuc057exi.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000183317.16
HGNCiHGNC:19987 EPHA10
OpenTargetsiENSG00000183317
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0196 Eukaryota
COG0515 LUCA
GeneTreeiENSGT00760000118975

Miscellaneous databases

ChiTaRSiEPHA10 human

Gene expression databases

BgeeiENSG00000183317 Expressed in 113 organ(s), highest expression level in sperm
ExpressionAtlasiH0YCC9 baseline and differential

Family and domain databases

CDDicd00063 FN3, 1 hit
InterProiView protein in InterPro
IPR027936 Eph_TM
IPR003961 FN3_dom
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
PfamiView protein in Pfam
PF14575 EphA2_TM, 1 hit
PF07714 Pkinase_Tyr, 1 hit
PRINTSiPR00109 TYRKINASE
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YCC9_HUMAN
AccessioniPrimary (citable) accession number: H0YCC9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 7, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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