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Protein
Submitted name:

Non-specific lipid-transfer protein

Gene

SCP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Non-specific lipid-transfer proteinImported
Gene namesi
Name:SCP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000116171.16
HGNCiHGNC:10606 SCP2

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000116171

PTM / Processingi

Proteomic databases

PeptideAtlasiH0YCB0
PRIDEiH0YCB0

Expressioni

Gene expression databases

BgeeiENSG00000116171 Expressed in 239 organ(s), highest expression level in liver
ExpressionAtlasiH0YCB0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YCB0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 171Thiolase_NInterPro annotationAdd BLAST166

Phylogenomic databases

GeneTreeiENSGT00530000062928

Family and domain databases

Gene3Di3.40.47.10, 2 hits
InterProiView protein in InterPro
IPR016039 Thiolase-like
IPR020615 Thiolase_acyl_enz_int_AS
IPR020616 Thiolase_N
PfamiView protein in Pfam
PF00108 Thiolase_N, 1 hit
SUPFAMiSSF53901 SSF53901, 1 hit
PROSITEiView protein in PROSITE
PS00098 THIOLASE_1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

H0YCB0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XPGAENSRDY PDLAEEAGKK ALADAQIPYS AVDQACVGYV FGDSTCGQRA
60 70 80 90 100
IYHSLGMTGI PIINVNNNCA TGSTALFMAR QLIQGGVAEC VLALGFEKMS
110 120 130 140 150
KGSLGIKFSD RTIPTDKHVD LLINKYGLSA HPVAPQMFGY AGKEHMEKYG
160 170 180 190 200
TKIEHFAKIG WKNHKHSVNN PPTSDGAAAA ILASEAFVQK YGLQSKAVEI
210 220 230 240
LAQEMMTDLP SSFEEKSIIK MVGFDMSKEA ARKCYEKSGL
Length:240
Mass (Da):25,884
Last modified:September 18, 2013 - v2
Checksum:i6F16ACB24B0275F7
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P22307NLTP_HUMAN
Non-specific lipid-transfer protein
SCP2
547Annotation score:
E9PLD1E9PLD1_HUMAN
Non-specific lipid-transfer protein
SCP2
366Annotation score:
H0YF61H0YF61_HUMAN
Non-specific lipid-transfer protein
SCP2
140Annotation score:
H0YD06H0YD06_HUMAN
Non-specific lipid-transfer protein
SCP2
78Annotation score:
H0YEU8H0YEU8_HUMAN
Non-specific lipid-transfer protein
SCP2
32Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei240Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC099677 Genomic DNA No translation available.
AL445183 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000529363; ENSP00000431279; ENSG00000116171
UCSCiuc057gqi.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC099677 Genomic DNA No translation available.
AL445183 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YCB0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH0YCB0
PRIDEiH0YCB0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000529363; ENSP00000431279; ENSG00000116171
UCSCiuc057gqi.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000116171.16
HGNCiHGNC:10606 SCP2
OpenTargetsiENSG00000116171
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00530000062928

Miscellaneous databases

ChiTaRSiSCP2 human

Gene expression databases

BgeeiENSG00000116171 Expressed in 239 organ(s), highest expression level in liver
ExpressionAtlasiH0YCB0 baseline and differential

Family and domain databases

Gene3Di3.40.47.10, 2 hits
InterProiView protein in InterPro
IPR016039 Thiolase-like
IPR020615 Thiolase_acyl_enz_int_AS
IPR020616 Thiolase_N
PfamiView protein in Pfam
PF00108 Thiolase_N, 1 hit
SUPFAMiSSF53901 SSF53901, 1 hit
PROSITEiView protein in PROSITE
PS00098 THIOLASE_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YCB0_HUMAN
AccessioniPrimary (citable) accession number: H0YCB0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: September 18, 2013
Last modified: November 7, 2018
This is version 40 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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