UniProtKB - H0YBS9 (H0YBS9_HUMAN)
Protein
Submitted name:
NEDD4-like E3 ubiquitin-protein ligase WWP1
Gene
WWP1
Organism
Homo sapiens (Human)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
GO - Molecular functioni
- ubiquitin-protein transferase activity Source: InterPro
Keywordsi
Biological process | Ubl conjugation pathwayPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: NEDD4-like E3 ubiquitin-protein ligase WWP1Imported |
Gene namesi | Name:WWP1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:17004, WWP1 |
VEuPathDBi | HostDB:ENSG00000123124.13 |
PTM / Processingi
Proteomic databases
MaxQBi | H0YBS9 |
PeptideAtlasi | H0YBS9 |
PRIDEi | H0YBS9 |
ProteomicsDBi | 36825 |
Expressioni
Gene expression databases
Bgeei | ENSG00000123124, Expressed in skeletal muscle tissue of rectus abdominis and 259 other tissues |
ExpressionAtlasi | H0YBS9, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 55 | HECTInterPro annotationAdd BLAST | 55 |
Phylogenomic databases
GeneTreei | ENSGT00940000154635 |
HOGENOMi | CLU_3037649_0_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR000569, HECT_dom IPR035983, Hect_E3_ubiquitin_ligase |
Pfami | View protein in Pfam PF00632, HECT, 1 hit |
SUPFAMi | SSF56204, SSF56204, 1 hit |
PROSITEi | View protein in PROSITE PS50237, HECT, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
H0YBS9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
VKETDNEVRM RLLQFVTGTC RLPLGGFAEL MGSNGPQKFC IEKVGKDTWL
PRSHT
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9H0M0 | WWP1_HUMAN | NEDD4-like E3 ubiquitin-protein lig... | WWP1 | 922 | Annotation score: | ||
H0YBA4 | H0YBA4_HUMAN | NEDD4-like E3 ubiquitin-protein lig... | WWP1 | 232 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC083845 Genomic DNA No translation available. AC103760 Genomic DNA No translation available. AC103817 Genomic DNA No translation available. KF458790 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000520798; ENSP00000430228; ENSG00000123124 |
UCSCi | uc064oez.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC083845 Genomic DNA No translation available. AC103760 Genomic DNA No translation available. AC103817 Genomic DNA No translation available. KF458790 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | H0YBS9 |
PeptideAtlasi | H0YBS9 |
PRIDEi | H0YBS9 |
ProteomicsDBi | 36825 |
Protocols and materials databases
Antibodypediai | 25465, 147 antibodies |
Genome annotation databases
Ensembli | ENST00000520798; ENSP00000430228; ENSG00000123124 |
UCSCi | uc064oez.1, human |
Organism-specific databases
HGNCi | HGNC:17004, WWP1 |
OpenTargetsi | ENSG00000123124 |
VEuPathDBi | HostDB:ENSG00000123124.13 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154635 |
HOGENOMi | CLU_3037649_0_0_1 |
Miscellaneous databases
ChiTaRSi | WWP1, human |
Gene expression databases
Bgeei | ENSG00000123124, Expressed in skeletal muscle tissue of rectus abdominis and 259 other tissues |
ExpressionAtlasi | H0YBS9, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR000569, HECT_dom IPR035983, Hect_E3_ubiquitin_ligase |
Pfami | View protein in Pfam PF00632, HECT, 1 hit |
SUPFAMi | SSF56204, SSF56204, 1 hit |
PROSITEi | View protein in PROSITE PS50237, HECT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H0YBS9_HUMAN | |
Accessioni | H0YBS9Primary (citable) accession number: H0YBS9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | April 7, 2021 | |
This is version 62 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |