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Protein
Submitted name:

Thyroglobulin

Gene

TG

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Protein family/group databases

ESTHERihuman-TMCO4 Duf_726

Names & Taxonomyi

Protein namesi
Submitted name:
ThyroglobulinImported
Gene namesi
Name:TGImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000042832.11
HGNCiHGNC:11764 TG

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000042832

PTM / Processingi

Proteomic databases

PeptideAtlasiH0YBR7
PRIDEiH0YBR7

Expressioni

Gene expression databases

BgeeiENSG00000042832 Expressed in 103 organ(s), highest expression level in thyroid gland
ExpressionAtlasiH0YBR7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YBR7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 67COesteraseInterPro annotationAdd BLAST64

Phylogenomic databases

GeneTreeiENSGT00680000100015

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR002018 CarbesteraseB
PfamiView protein in Pfam
PF00135 COesterase, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

H0YBR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
SDARVEAAAT WYYSLEHSTD DYASFSRALE NATRDYFIIC PIIDMASAWA
60 70 80 90 100
KRARGNVFMY HAPENYGHGR NPNYPYEFSR KVPTFATPWP DFVPRAGGEN
110 120 130 140 150
YKEFSELLPN RQGLKKADCS FWSKYISSLK TSADGAKGGQ SAESEEEELT
160 170
AGSGLREDLL SLQEPGSKTY SK
Length:172
Mass (Da):19,291
Last modified:February 22, 2012 - v1
Checksum:i9B2E8A05F01C1819
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P01266THYG_HUMAN
Thyroglobulin
TG
2,768Annotation score:
H0YB42H0YB42_HUMAN
Thyroglobulin
TG
147Annotation score:
H0YBJ2H0YBJ2_HUMAN
Thyroglobulin
TG
226Annotation score:
E5RG33E5RG33_HUMAN
Thyroglobulin
TG
59Annotation score:
H0YBY1H0YBY1_HUMAN
Thyroglobulin
TG
1,224Annotation score:
E7EVM0E7EVM0_HUMAN
Thyroglobulin
TG
901Annotation score:
H0YBL4H0YBL4_HUMAN
Thyroglobulin
TG
194Annotation score:
H0YBQ6H0YBQ6_HUMAN
Thyroglobulin
TG
74Annotation score:
H0YBC5H0YBC5_HUMAN
Thyroglobulin
TG
62Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF230666 Genomic DNA No translation available.
AF230667 Genomic DNA No translation available.
AF235100 Genomic DNA No translation available.
AF305872 Genomic DNA No translation available.
KF458854 Genomic DNA No translation available.
KF495732 Genomic DNA No translation available.
KF511066 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000521107; ENSP00000430161; ENSG00000042832
UCSCiuc064qkn.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF230666 Genomic DNA No translation available.
AF230667 Genomic DNA No translation available.
AF235100 Genomic DNA No translation available.
AF305872 Genomic DNA No translation available.
KF458854 Genomic DNA No translation available.
KF495732 Genomic DNA No translation available.
KF511066 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YBR7
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

ESTHERihuman-TMCO4 Duf_726

Proteomic databases

PeptideAtlasiH0YBR7
PRIDEiH0YBR7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000521107; ENSP00000430161; ENSG00000042832
UCSCiuc064qkn.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000042832.11
HGNCiHGNC:11764 TG
OpenTargetsiENSG00000042832
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00680000100015

Miscellaneous databases

ChiTaRSiTG human

Gene expression databases

BgeeiENSG00000042832 Expressed in 103 organ(s), highest expression level in thyroid gland
ExpressionAtlasiH0YBR7 baseline and differential

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR002018 CarbesteraseB
PfamiView protein in Pfam
PF00135 COesterase, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YBR7_HUMAN
AccessioniPrimary (citable) accession number: H0YBR7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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