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Protein
Submitted name:

Transcription factor E2F5

Gene

E2F5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor E2F5Imported
Gene namesi
Name:E2F5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000133740.10
HGNCiHGNC:3119 E2F5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000133740

PTM / Processingi

Proteomic databases

MaxQBiH0YBK0
PeptideAtlasiH0YBK0
PRIDEiH0YBK0

Expressioni

Gene expression databases

BgeeiENSG00000133740 Expressed in 152 organ(s), highest expression level in kidney
ExpressionAtlasiH0YBK0 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH0YBK0
SMRiH0YBK0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 66E2F_CC-MBInterPro annotationAdd BLAST63

Phylogenomic databases

eggNOGiKOG2577 Eukaryota
ENOG410XNYI LUCA
GeneTreeiENSGT00550000074403

Family and domain databases

CDDicd14660 E2F_DD, 1 hit
InterProiView protein in InterPro
IPR015633 E2F
IPR037241 E2F-DP_heterodim
IPR028316 E2F5
IPR032198 E2F_CC-MB
PANTHERiPTHR12081 PTHR12081, 2 hits
PTHR12081:SF35 PTHR12081:SF35, 2 hits
PfamiView protein in Pfam
PF16421 E2F_CC-MB, 1 hit
SUPFAMiSSF144074 SSF144074, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H0YBK0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
SYDSTFSYVT HEDICNCFNG DTLLAIQAPS GTQLEVPIPE MGQNGQKKYQ
60 70 80 90 100
INLKSHSGPI HVLLINKESS SSKPVVFPVP PPDDLTQPSS QSLTPVTPQK
110 120 130 140 150
SSMATQNLPE QHVSERSQAL QQTSATDISS AGSISGDIID ELMSSDVFPL
160 170 180
LRLSPTPADD YNFNLDDNEG VCDLFDVQIL NY
Length:182
Mass (Da):19,800
Last modified:February 22, 2012 - v1
Checksum:i58F9B6CEB3E1A18F
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q15329E2F5_HUMAN
Transcription factor E2F5
E2F5
346Annotation score:
E5RHD4E5RHD4_HUMAN
Transcription factor E2F5
E2F5
173Annotation score:
C9JYE9C9JYE9_HUMAN
Transcription factor E2F5
E2F5
249Annotation score:
H0YBW8H0YBW8_HUMAN
Transcription factor E2F5
E2F5
130Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011773 Genomic DNA No translation available.
KF573693 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000518234; ENSP00000429669; ENSG00000133740
UCSCiuc064ocg.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011773 Genomic DNA No translation available.
KF573693 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YBK0
SMRiH0YBK0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0YBK0
PeptideAtlasiH0YBK0
PRIDEiH0YBK0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000518234; ENSP00000429669; ENSG00000133740
UCSCiuc064ocg.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000133740.10
HGNCiHGNC:3119 E2F5
OpenTargetsiENSG00000133740
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2577 Eukaryota
ENOG410XNYI LUCA
GeneTreeiENSGT00550000074403

Miscellaneous databases

ChiTaRSiE2F5 human

Gene expression databases

BgeeiENSG00000133740 Expressed in 152 organ(s), highest expression level in kidney
ExpressionAtlasiH0YBK0 baseline and differential

Family and domain databases

CDDicd14660 E2F_DD, 1 hit
InterProiView protein in InterPro
IPR015633 E2F
IPR037241 E2F-DP_heterodim
IPR028316 E2F5
IPR032198 E2F_CC-MB
PANTHERiPTHR12081 PTHR12081, 2 hits
PTHR12081:SF35 PTHR12081:SF35, 2 hits
PfamiView protein in Pfam
PF16421 E2F_CC-MB, 1 hit
SUPFAMiSSF144074 SSF144074, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YBK0_HUMAN
AccessioniPrimary (citable) accession number: H0YBK0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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