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Protein
Submitted name:

Myc proto-oncogene protein

Gene

MYC

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Myc proto-oncogene proteinImported
Gene namesi
Name:MYCImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000136997.15
HGNCiHGNC:7553 MYC

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000136997

PTM / Processingi

Proteomic databases

MaxQBiH0YBG3
PeptideAtlasiH0YBG3
PRIDEiH0YBG3

Expressioni

Gene expression databases

BgeeiENSG00000136997 Expressed in 216 organ(s), highest expression level in thoracic mammary gland
ExpressionAtlasiH0YBG3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YBG3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 180Myc_NInterPro annotationAdd BLAST166

Phylogenomic databases

eggNOGiENOG410IFSM Eukaryota
ENOG41124Q3 LUCA
GeneTreeiENSGT00510000046414

Family and domain databases

InterProiView protein in InterPro
IPR002418 Tscrpt_reg_Myc
IPR012682 Tscrpt_reg_Myc_N
PfamiView protein in Pfam
PF01056 Myc_N, 1 hit
PRINTSiPR00044 LEUZIPPRMYC

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

H0YBG3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
LDFFRVVENQ PPATMPLNVS FTNRNYDLDY DSVQPYFYCD EEENFYQQQQ
60 70 80 90 100
QSELQPPAPS EDIWKKFELL PTPPLSPSRR SGLCSPSYVA VTPFSLRGDN
110 120 130 140 150
DGGGGSFSTA DQLEMVTELL GGDMVNQSFI CDPDDETFIK NIIIQDCMWS
160 170 180
GFSAAAKLVS EKLASYQAAR KDSGSPNPAR GHSV
Length:184
Mass (Da):20,467
Last modified:February 22, 2012 - v1
Checksum:i75477C392B089156
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P01106MYC_HUMAN
Myc proto-oncogene protein
MYC BHLHE39
439Annotation score:
A0A087WUS5A0A087WUS5_HUMAN
Myc proto-oncogene protein
MYC
454Annotation score:
Q14899Q14899_HUMAN
Myc proto-oncogene protein
MYC MRTL
114Annotation score:
H0YBT0H0YBT0_HUMAN
Myc proto-oncogene protein
MYC
453Annotation score:
A0A087WVR4A0A087WVR4_HUMAN
Myc proto-oncogene protein
MYC
454Annotation score:
A0A0B4J1R1A0A0B4J1R1_HUMAN
Myc proto-oncogene protein
MYC hCG_15917
257Annotation score:
E5RGD7E5RGD7_HUMAN
Myc proto-oncogene protein
MYC
59Annotation score:
Q16591Q16591_HUMAN
Myc protein
MYC
188Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei184Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC103819 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000517291; ENSP00000429441; ENSG00000136997
UCSCiuc003ysh.2 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC103819 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YBG3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0YBG3
PeptideAtlasiH0YBG3
PRIDEiH0YBG3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000517291; ENSP00000429441; ENSG00000136997
UCSCiuc003ysh.2 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000136997.15
HGNCiHGNC:7553 MYC
OpenTargetsiENSG00000136997
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFSM Eukaryota
ENOG41124Q3 LUCA
GeneTreeiENSGT00510000046414

Miscellaneous databases

ChiTaRSiMYC human

Gene expression databases

BgeeiENSG00000136997 Expressed in 216 organ(s), highest expression level in thoracic mammary gland
ExpressionAtlasiH0YBG3 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR002418 Tscrpt_reg_Myc
IPR012682 Tscrpt_reg_Myc_N
PfamiView protein in Pfam
PF01056 Myc_N, 1 hit
PRINTSiPR00044 LEUZIPPRMYC
ProtoNetiSearch...

Entry informationi

Entry nameiH0YBG3_HUMAN
AccessioniPrimary (citable) accession number: H0YBG3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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