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Protein
Submitted name:

Matrilin-2

Gene

MATN2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Matrilin-2Imported
Gene namesi
Name:MATN2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000132561.13
HGNCiHGNC:6908 MATN2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000132561

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiH0YBD5
PRIDEiH0YBD5

Expressioni

Gene expression databases

BgeeiENSG00000132561 Expressed in 229 organ(s), highest expression level in tibia
ExpressionAtlasiH0YBD5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YBD5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 41EGF_CAInterPro annotationAdd BLAST41
Domaini4 – 41EGF-likeInterPro annotationAdd BLAST38
Domaini42 – 82EGF_CAInterPro annotationAdd BLAST41
Domaini45 – 82EGF-likeInterPro annotationAdd BLAST38
Domaini83 – 123EGF_CAInterPro annotationAdd BLAST41
Domaini86 – 123EGF-likeInterPro annotationAdd BLAST38

Keywords - Domaini

EGF-like domainSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IR7H Eukaryota
ENOG410XSTY LUCA
GeneTreeiENSGT00930000150889

Family and domain databases

InterProiView protein in InterPro
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR009030 Growth_fac_rcpt_cys_sf
IPR030747 Matrilin-2
PANTHERiPTHR44734:SF1 PTHR44734:SF1, 1 hit
PfamiView protein in Pfam
PF07645 EGF_CA, 2 hits
SMARTiView protein in SMART
SM00181 EGF, 3 hits
SM00179 EGF_CA, 3 hits
SUPFAMiSSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 1 hit
PS01186 EGF_2, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

H0YBD5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XVDYCLLSDH GCEYSCVNMD RSFACQCPEG HVLRSDGKTC AKLDSCALGD
60 70 80 90 100
HGCEHSCVSS EDSFVCQCFE GYILREDGKT CRRKDVCQAI DHGCEHICVN
110 120 130 140 150
SDDSYTCECL EGFRLAEDGK RCRSKMSANQ PTMAANTFVL IMGIPTSANA

QRDLF
Length:155
Mass (Da):17,103
Last modified:February 22, 2012 - v1
Checksum:i23D23637AF711333
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O00339MATN2_HUMAN
Matrilin-2
MATN2 UNQ193/PRO219
956Annotation score:
H0YBJ4H0YBJ4_HUMAN
Matrilin-2
MATN2
720Annotation score:
H0YBM3H0YBM3_HUMAN
Matrilin-2
MATN2
195Annotation score:
H0YBV5H0YBV5_HUMAN
Matrilin-2
MATN2
181Annotation score:
H0YBN2H0YBN2_HUMAN
Matrilin-2
MATN2
183Annotation score:
E5RJM4E5RJM4_HUMAN
Matrilin-2
MATN2
115Annotation score:
H0YBU5H0YBU5_HUMAN
Matrilin-2
MATN2
176Annotation score:
H0YBF2H0YBF2_HUMAN
Matrilin-2
MATN2
131Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002906 Genomic DNA No translation available.
AP003352 Genomic DNA No translation available.
KC877283 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000521952; ENSP00000429256; ENSG00000132561
UCSCiuc064ovw.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002906 Genomic DNA No translation available.
AP003352 Genomic DNA No translation available.
KC877283 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YBD5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH0YBD5
PRIDEiH0YBD5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000521952; ENSP00000429256; ENSG00000132561
UCSCiuc064ovw.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000132561.13
HGNCiHGNC:6908 MATN2
OpenTargetsiENSG00000132561
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IR7H Eukaryota
ENOG410XSTY LUCA
GeneTreeiENSGT00930000150889

Miscellaneous databases

ChiTaRSiMATN2 human

Gene expression databases

BgeeiENSG00000132561 Expressed in 229 organ(s), highest expression level in tibia
ExpressionAtlasiH0YBD5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR009030 Growth_fac_rcpt_cys_sf
IPR030747 Matrilin-2
PANTHERiPTHR44734:SF1 PTHR44734:SF1, 1 hit
PfamiView protein in Pfam
PF07645 EGF_CA, 2 hits
SMARTiView protein in SMART
SM00181 EGF, 3 hits
SM00179 EGF_CA, 3 hits
SUPFAMiSSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 1 hit
PS01186 EGF_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiH0YBD5_HUMAN
AccessioniPrimary (citable) accession number: H0YBD5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 7, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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