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Protein
Submitted name:

Protein KIBRA

Gene

WWC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Protein KIBRAImported
Gene namesi
Name:WWC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000113645.13
HGNCiHGNC:29435 WWC1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000113645

PTM / Processingi

Proteomic databases

MaxQBiH0YAU4
PeptideAtlasiH0YAU4
PRIDEiH0YAU4

Expressioni

Gene expression databases

BgeeiENSG00000113645 Expressed in 201 organ(s), highest expression level in oviduct epithelium
ExpressionAtlasiH0YAU4 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 109C2InterPro annotationAdd BLAST82

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili170 – 200Sequence analysisAdd BLAST31
Coiled coili334 – 361Sequence analysisAdd BLAST28
Coiled coili376 – 396Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3209 Eukaryota
COG5021 LUCA
GeneTreeiENSGT00410000025556

Family and domain databases

CDDicd08680 C2_Kibra, 1 hit
Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR037771 C2_WWC
PfamiView protein in Pfam
PF00168 C2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

H0YAU4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
FAILIIQLSN LSALLQQQDQ KVNIRVAVLP CSESTTCLFR TRPLDASDTL
60 70 80 90 100
VFNEVFWVSM SYPALHQKTL RVDVCTTDRS HLEECLGGAQ ISLAEVCRSG
110 120 130 140 150
ERSTRWYNLL SYKYLKKQSR ELKPVGVMAP ASGPASTDAV SALLEQTAVE
160 170 180 190 200
LEKRQEGRSS TQTLEDSWRY EETSENEAVA EEEEEEVEEE EGEEDVFTEK
210 220 230 240 250
ASPDMDGYPA LKVDKETNTE TPAPSPTVVR PKDRRVGTPS QGPFLRGSTI
260 270 280 290 300
IRSKTFSPGP QSQYVCRLNR SDSDSSTLSK KPPFVRNSLE RRSVRMKRPS
310 320 330 340 350
PPPQPSSVKS LRSERLIRTS LDLELDLQAT RTWHSQLTQE ISVLKELKEQ
360 370 380 390 400
LEQAKSHGEK ELPQWLREDE RFRLLLRMLE KRMDRAEHKG ELQTDKMMRA
410 420 430 440
AAKDVHRLRG QSCKEPPEVQ SFREKMAFFT RPRMNIPALS ADDV
Length:444
Mass (Da):50,569
Last modified:February 22, 2012 - v1
Checksum:i1292D38B5A6AC544
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8IX03KIBRA_HUMAN
Protein KIBRA
WWC1 KIAA0869
1,113Annotation score:
H3BLZ3H3BLZ3_HUMAN
Protein KIBRA
WWC1
1,080Annotation score:
H0YBE8H0YBE8_HUMAN
Protein KIBRA
WWC1
889Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020894 Genomic DNA No translation available.
AC026689 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000524038; ENSP00000428084; ENSG00000113645
UCSCiuc063jlf.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020894 Genomic DNA No translation available.
AC026689 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0YAU4
PeptideAtlasiH0YAU4
PRIDEiH0YAU4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000524038; ENSP00000428084; ENSG00000113645
UCSCiuc063jlf.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000113645.13
HGNCiHGNC:29435 WWC1
OpenTargetsiENSG00000113645
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3209 Eukaryota
COG5021 LUCA
GeneTreeiENSGT00410000025556

Miscellaneous databases

ChiTaRSiWWC1 human

Gene expression databases

BgeeiENSG00000113645 Expressed in 201 organ(s), highest expression level in oviduct epithelium
ExpressionAtlasiH0YAU4 baseline and differential

Family and domain databases

CDDicd08680 C2_Kibra, 1 hit
Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR037771 C2_WWC
PfamiView protein in Pfam
PF00168 C2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YAU4_HUMAN
AccessioniPrimary (citable) accession number: H0YAU4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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