Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

ER membrane protein complex subunit 2

Gene

EMC2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
ER membrane protein complex subunit 2Imported
Gene namesi
Name:EMC2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000104412.7
HGNCiHGNC:28963 EMC2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000104412

PTM / Processingi

Proteomic databases

MaxQBiH0YAS9
PeptideAtlasiH0YAS9
PRIDEiH0YAS9

Expressioni

Gene expression databases

BgeeiENSG00000104412 Expressed in 236 organ(s), highest expression level in corpus callosum
ExpressionAtlasiH0YAS9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YAS9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 68TPR_REGIONInterPro annotationAdd BLAST34
Repeati35 – 68TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili78 – 98Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3060 Eukaryota
ENOG410YT6B LUCA
GeneTreeiENSGT00390000011922

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR039856 EMC2-like
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PANTHERiPTHR12760 PTHR12760, 1 hit
SUPFAMiSSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50005 TPR, 1 hit
PS50293 TPR_REGION, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

H0YAS9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XIIYEQVMIA ALDYGRDDLA LFCLQELRRQ FPGSHRVKRL TGMRFEAMER
60 70 80 90 100
YDDAIQLYDR ILQEDPTNTA ARKRKIAIRK AQGKNVEAIR ELNEYLEQFV
110 120 130
GDQEAWHELA ELYINEHDLQ VEVRRKPNIL LRLSK
Length:135
Mass (Da):16,043
Last modified:February 22, 2012 - v1
Checksum:i21DC254F72C0574D
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q15006EMC2_HUMAN
ER membrane protein complex subunit...
EMC2 KIAA0103, TTC35
297Annotation score:
E5RGJ2E5RGJ2_HUMAN
ER membrane protein complex subunit...
EMC2
112Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei135Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022634 Genomic DNA No translation available.
AP002088 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000519642; ENSP00000428040; ENSG00000104412
UCSCiuc064pnd.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC022634 Genomic DNA No translation available.
AP002088 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YAS9
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0YAS9
PeptideAtlasiH0YAS9
PRIDEiH0YAS9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000519642; ENSP00000428040; ENSG00000104412
UCSCiuc064pnd.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000104412.7
HGNCiHGNC:28963 EMC2
OpenTargetsiENSG00000104412
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3060 Eukaryota
ENOG410YT6B LUCA
GeneTreeiENSGT00390000011922

Miscellaneous databases

ChiTaRSiEMC2 human

Gene expression databases

BgeeiENSG00000104412 Expressed in 236 organ(s), highest expression level in corpus callosum
ExpressionAtlasiH0YAS9 baseline and differential

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR039856 EMC2-like
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PANTHERiPTHR12760 PTHR12760, 1 hit
SUPFAMiSSF48452 SSF48452, 1 hit
PROSITEiView protein in PROSITE
PS50005 TPR, 1 hit
PS50293 TPR_REGION, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0YAS9_HUMAN
AccessioniPrimary (citable) accession number: H0YAS9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 7, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again