UniProtKB - H0YAH4 (H0YAH4_HUMAN)
Protein
Submitted name:
Zinc transporter 5
Gene
SLC30A5
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- cation transmembrane transporter activity Source: InterPro
GO - Biological processi
- zinc ion transport Source: UniProtKB-KW
Keywordsi
Biological process | Ion transport, Transport, Zinc transportARBA annotation |
Ligand | Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc transporter 5Imported |
Gene namesi | Name:SLC30A5Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000145740.18 |
HGNCi | HGNC:19089, SLC30A5 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 21 – 44 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000145740, Expressed in amniotic fluid and 232 other tissues |
ExpressionAtlasi | H0YAH4, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. [View classification]ARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000155754 |
HOGENOMi | CLU_2873530_0_0_1 |
Family and domain databases
Gene3Di | 1.20.1510.10, 1 hit |
InterProi | View protein in InterPro IPR002524, Cation_efflux IPR027469, Cation_efflux_TMD_sf |
Pfami | View protein in Pfam PF01545, Cation_efflux, 1 hit |
SUPFAMi | SSF161111, SSF161111, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
H0YAH4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XLFAALMSRW KATRIFSYGY GRIEILSGFI NGLFLIVIAF FVFMESVARL
60
IDPPELDTHM LTPCP
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8TAD4 | ZNT5_HUMAN | Zinc transporter 5 | SLC30A5 ZNT5, ZNTL1, ZTL1, UNQ863/PRO1879 | 765 | Annotation score: | ||
Q9BY48 | Q9BY48_HUMAN | Putative disease resistance protein | SLC30A5 | 360 | Annotation score: | ||
H0Y957 | H0Y957_HUMAN | Zinc transporter 5 | SLC30A5 | 84 | Annotation score: | ||
D6REM2 | D6REM2_HUMAN | Zinc transporter 5 | SLC30A5 | 71 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC010273 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000513937; ENSP00000427111; ENSG00000145740 |
UCSCi | uc063eeq.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC010273 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | H0YAH4 |
PRIDEi | H0YAH4 |
ProteomicsDBi | 36378 |
Genome annotation databases
Ensembli | ENST00000513937; ENSP00000427111; ENSG00000145740 |
UCSCi | uc063eeq.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000145740.18 |
HGNCi | HGNC:19089, SLC30A5 |
OpenTargetsi | ENSG00000145740 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155754 |
HOGENOMi | CLU_2873530_0_0_1 |
Miscellaneous databases
ChiTaRSi | SLC30A5, human |
Gene expression databases
Bgeei | ENSG00000145740, Expressed in amniotic fluid and 232 other tissues |
ExpressionAtlasi | H0YAH4, baseline and differential |
Family and domain databases
Gene3Di | 1.20.1510.10, 1 hit |
InterProi | View protein in InterPro IPR002524, Cation_efflux IPR027469, Cation_efflux_TMD_sf |
Pfami | View protein in Pfam PF01545, Cation_efflux, 1 hit |
SUPFAMi | SSF161111, SSF161111, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | H0YAH4_HUMAN | |
Accessioni | H0YAH4Primary (citable) accession number: H0YAH4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | October 7, 2020 | |
This is version 47 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |