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UniProtKB - H0YAF8 (H0YAF8_HUMAN)
Protein
Guanine nucleotide-binding protein subunit beta-2-like 1
Gene
RACK1
Organism
Homo sapiens (Human)
Status
Functioni
Keywordsi
Molecular function | Developmental protein, Ribonucleoprotein, Ribosomal proteinARBA annotation |
Biological process | GastrulationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Guanine nucleotide-binding protein subunit beta-2-like 1ARBA annotation |
Gene namesi | Name:RACK1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:4399, RACK1 |
VEuPathDBi | HostDB:ENSG00000204628 |
PTM / Processingi
Proteomic databases
MaxQBi | H0YAF8 |
PeptideAtlasi | H0YAF8 |
PRIDEi | H0YAF8 |
ProteomicsDBi | 36362 |
PTM databases
SwissPalmi | H0YAF8 |
Expressioni
Gene expression databases
Bgeei | ENSG00000204628, Expressed in female gonad and 258 other tissues |
ExpressionAtlasi | H0YAF8, baseline and differential |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 1 – 18 | WDPROSITE-ProRule annotationAdd BLAST | 18 | |
Repeati | 19 – 51 | WDPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 168 – 198 | WDPROSITE-ProRule annotationAdd BLAST | 31 |
Sequence similaritiesi
Keywords - Domaini
WD repeatPROSITE-ProRule annotationPhylogenomic databases
GeneTreei | ENSGT00940000154461 |
Family and domain databases
Gene3Di | 2.130.10.10, 2 hits |
InterProi | View protein in InterPro IPR045223, Asc1/RACK1 IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR036322, WD40_repeat_dom_sf |
PANTHERi | PTHR19868, PTHR19868, 2 hits |
Pfami | View protein in Pfam PF00400, WD40, 4 hits |
SMARTi | View protein in SMART SM00320, WD40, 4 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS50082, WD_REPEATS_2, 3 hits |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 21 potential isoforms that are computationally mapped.Show allAlign All
H0YAF8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XDGTLRLWDL TTGTTTRRFV GHTKDVLSVA FSSDNRQIVS GSRDKTIKLW
60 70 80 90 100
NTLGVCKYTV QDESHSEWVS CVRFSPNSSN PIIVSCGWDK LVKDGQAMLW
110 120 130 140 150
DLNEGKHLYT LDGGDIINAL CFSPNRYWLC AATGPSIKIW DLEGKIIVDE
160 170 180 190
LKQEVISTSS KAEPPQCTSL AWSADGQTLF AGYTDNLVRV WQVTIGTR
Computationally mapped potential isoform sequencesi
There are 21 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP63244 | RACK1_HUMAN | Receptor of activated protein C kin... | RACK1 GNB2L1, HLC7, PIG21 | 317 | Annotation score: | ||
D6R9L0 | D6R9L0_HUMAN | Guanine nucleotide-binding protein ... | RACK1 | 300 | Annotation score: | ||
D6RAC2 | D6RAC2_HUMAN | Guanine nucleotide-binding protein ... | RACK1 | 269 | Annotation score: | ||
D6REE5 | D6REE5_HUMAN | Guanine nucleotide-binding protein ... | RACK1 | 321 | Annotation score: | ||
D6RFX4 | D6RFX4_HUMAN | Guanine nucleotide-binding protein ... | RACK1 | 194 | Annotation score: | ||
J3KPE3 | J3KPE3_HUMAN | Guanine nucleotide-binding protein ... | RACK1 | 273 | Annotation score: | ||
D6R9Z1 | D6R9Z1_HUMAN | Guanine nucleotide-binding protein ... | RACK1 | 236 | Annotation score: | ||
H0Y8R5 | H0Y8R5_HUMAN | Guanine nucleotide-binding protein ... | RACK1 | 138 | Annotation score: | ||
H0Y8W2 | H0Y8W2_HUMAN | Guanine nucleotide-binding protein ... | RACK1 | 274 | Annotation score: | ||
H0YAM7 | H0YAM7_HUMAN | Guanine nucleotide-binding protein ... | RACK1 | 247 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC008443 Genomic DNA No translation available. KC877161 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000502905; ENSP00000426960; ENSG00000204628 |
UCSCi | uc063kxc.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC008443 Genomic DNA No translation available. KC877161 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
PTM databases
SwissPalmi | H0YAF8 |
Proteomic databases
MaxQBi | H0YAF8 |
PeptideAtlasi | H0YAF8 |
PRIDEi | H0YAF8 |
ProteomicsDBi | 36362 |
Protocols and materials databases
Antibodypediai | 3802, 456 antibodies from 44 providers |
Genome annotation databases
Ensembli | ENST00000502905; ENSP00000426960; ENSG00000204628 |
UCSCi | uc063kxc.1, human |
Organism-specific databases
HGNCi | HGNC:4399, RACK1 |
OpenTargetsi | ENSG00000204628 |
VEuPathDBi | HostDB:ENSG00000204628 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154461 |
Miscellaneous databases
ChiTaRSi | RACK1, human |
Gene expression databases
Bgeei | ENSG00000204628, Expressed in female gonad and 258 other tissues |
ExpressionAtlasi | H0YAF8, baseline and differential |
Family and domain databases
Gene3Di | 2.130.10.10, 2 hits |
InterProi | View protein in InterPro IPR045223, Asc1/RACK1 IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR036322, WD40_repeat_dom_sf |
PANTHERi | PTHR19868, PTHR19868, 2 hits |
Pfami | View protein in Pfam PF00400, WD40, 4 hits |
SMARTi | View protein in SMART SM00320, WD40, 4 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS50082, WD_REPEATS_2, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | H0YAF8_HUMAN | |
Accessioni | H0YAF8Primary (citable) accession number: H0YAF8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | January 19, 2022 | |
This is version 61 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |