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Protein
Submitted name:

RUN and FYVE domain-containing protein 1

Gene

RUFY1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
RUN and FYVE domain-containing protein 1Imported
Gene namesi
Name:RUFY1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000176783.14
HGNCiHGNC:19760 RUFY1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000176783

PTM / Processingi

Proteomic databases

PeptideAtlasiH0YA47
PRIDEiH0YA47

Expressioni

Gene expression databases

BgeeiENSG00000176783 Expressed in 220 organ(s), highest expression level in lower esophagus muscularis layer
ExpressionAtlasiH0YA47 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0YA47
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili34 – 61Sequence analysisAdd BLAST28
Coiled coili113 – 133Sequence analysisAdd BLAST21
Coiled coili148 – 168Sequence analysisAdd BLAST21
Coiled coili176 – 203Sequence analysisAdd BLAST28
Coiled coili208 – 249Sequence analysisAdd BLAST42
Coiled coili253 – 290Sequence analysisAdd BLAST38

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00550000074558

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H0YA47-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XQDLDGGKEH ERITDVLDQK NYVEELNRHL SCTVGDLQTK IDGLEKTNSK
60 70 80 90 100
LQEEITKQDT KVELETYKQT RQGLDEMYSD VWKQLKEEKK VRLELEKELE
110 120 130 140 150
LQIGMKTEME IAMKLLEKDT HEKQDTLVAL RQQLEEVKAI NLQMFHKAQN
160 170 180 190 200
AESSLQQKNE AITSFEGKTN QVMSSMKQME ERLQHSERAR QGAEERSHKL
210 220 230 240 250
QQELGGRIGA LQLQLSQLHE QCSSLEKELK SEKEQRQALQ RELQHEKDTS
260 270 280 290 300
SLLRMELQQV EGLKKELREL QDEKAELQKI CEEQEQALQE MGLHLSQSKL
310 320
KMEDIKEVNQ ALKGHAWLKD DEATHCRQ
Length:328
Mass (Da):38,334
Last modified:February 22, 2012 - v1
Checksum:i31D411583647D828
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q96T51RUFY1_HUMAN
RUN and FYVE domain-containing prot...
RUFY1 RABIP4, ZFYVE12
708Annotation score:
H0YAC8H0YAC8_HUMAN
RUN and FYVE domain-containing prot...
RUFY1
271Annotation score:
J3KPP6J3KPP6_HUMAN
RUN and FYVE domain-containing prot...
RUFY1
324Annotation score:
H0Y9Y8H0Y9Y8_HUMAN
RUN and FYVE domain-containing prot...
RUFY1
219Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei328Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC136604 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000502434; ENSP00000426117; ENSG00000176783
UCSCiuc063kmn.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC136604 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0YA47
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH0YA47
PRIDEiH0YA47

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000502434; ENSP00000426117; ENSG00000176783
UCSCiuc063kmn.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000176783.14
HGNCiHGNC:19760 RUFY1
OpenTargetsiENSG00000176783
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00550000074558

Miscellaneous databases

ChiTaRSiRUFY1 human

Gene expression databases

BgeeiENSG00000176783 Expressed in 220 organ(s), highest expression level in lower esophagus muscularis layer
ExpressionAtlasiH0YA47 baseline and differential

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiH0YA47_HUMAN
AccessioniPrimary (citable) accession number: H0YA47
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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