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Protein
Submitted name:

Protocadherin-1

Gene

PCDH1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protocadherin-1Imported
Gene namesi
Name:PCDH1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000156453.13
HGNCiHGNC:8655 PCDH1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000156453

PTM / Processingi

Proteomic databases

MaxQBiH0Y9F5
PeptideAtlasiH0Y9F5
PRIDEiH0Y9F5

Expressioni

Gene expression databases

BgeeiENSG00000156453 Expressed in 214 organ(s), highest expression level in lower esophagus mucosa
ExpressionAtlasiH0Y9F5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y9F5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 82CAInterPro annotationAdd BLAST81

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410II7Q Eukaryota
ENOG410XPHP LUCA
GeneTreeiENSGT00920000148958

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
PfamiView protein in Pfam
PF00028 Cadherin, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 1 hit
SUPFAMiSSF49313 SSF49313, 1 hit
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H0Y9F5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XGPNGVASYE LQAGPEAQEL FGLQVAEDQE EKQPQLIVMG NLDRERWDSY
60 70 80 90 100
DLTIKVQDGG SPPRASSALL RVTVLDTNDN APKFERPSYE AELSENSPIG
110 120
HSVIQSLVDW DLEKRLRKKR ETDSRG
Length:126
Mass (Da):14,092
Last modified:February 22, 2012 - v1
Checksum:iDD685B46D75253EC
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q08174PCDH1_HUMAN
Protocadherin-1
PCDH1
1,060Annotation score:
D6RBG2D6RBG2_HUMAN
Protocadherin-1
PCDH1
150Annotation score:
D6RAX3D6RAX3_HUMAN
Protocadherin-1
PCDH1
382Annotation score:
H0Y9I5H0Y9I5_HUMAN
Protocadherin-1
PCDH1
17Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC094107 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000505937; ENSP00000424004; ENSG00000156453
UCSCiuc063icz.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC094107 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y9F5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0Y9F5
PeptideAtlasiH0Y9F5
PRIDEiH0Y9F5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000505937; ENSP00000424004; ENSG00000156453
UCSCiuc063icz.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000156453.13
HGNCiHGNC:8655 PCDH1
OpenTargetsiENSG00000156453
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410II7Q Eukaryota
ENOG410XPHP LUCA
GeneTreeiENSGT00920000148958

Miscellaneous databases

ChiTaRSiPCDH1 human

Gene expression databases

BgeeiENSG00000156453 Expressed in 214 organ(s), highest expression level in lower esophagus mucosa
ExpressionAtlasiH0Y9F5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
PfamiView protein in Pfam
PF00028 Cadherin, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 1 hit
SUPFAMiSSF49313 SSF49313, 1 hit
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y9F5_HUMAN
AccessioniPrimary (citable) accession number: H0Y9F5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 7, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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