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Protein
Submitted name:

Collagen alpha-5(VI) chain

Gene

COL6A5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Collagen alpha-5(VI) chainImported
Gene namesi
Name:COL6A5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000172752.14
HGNCiHGNC:26674 COL6A5

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172752

PTM / Processingi

Proteomic databases

PeptideAtlasiH0Y935
PRIDEiH0Y935

Expressioni

Gene expression databases

BgeeiENSG00000172752 Expressed in 38 organ(s), highest expression level in upper lobe of left lung
ExpressionAtlasiH0Y935 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y935
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 217VWFAInterPro annotationAdd BLAST208
Domaini215 – 406VWFAInterPro annotationAdd BLAST192
Domaini543 – 739VWFAInterPro annotationAdd BLAST197

Phylogenomic databases

eggNOGiKOG3544 Eukaryota
ENOG410XNMM LUCA
GeneTreeiENSGT00760000119000

Family and domain databases

Gene3Di3.40.50.410, 3 hits
InterProiView protein in InterPro
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF00092 VWA, 3 hits
SMARTiView protein in SMART
SM00327 VWA, 3 hits
SUPFAMiSSF53300 SSF53300, 3 hits
PROSITEiView protein in PROSITE
PS50234 VWFA, 3 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H0Y935-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XEKCPAYPTE LVFALDNSYD VTEESFNKTR DIITSIVNDL NIRENNCPVG
60 70 80 90 100
ARVAMVSYNS GTSYLIRWSD YNRKKQLLQQ LSQIKYQDTT EPRDVGNAMR
110 120 130 140 150
FVTRNVFKRT YAGANVRRVA VFFSNGQTAS RSSIITATME FSALDISPTV
160 170 180 190 200
FAFDERVFLE AFGFDNTGTF QVIPVPPNGE NQTLERLRRC ALCYDKCFPN
210 220 230 240 250
ACIREAFLPE DSYMDVVFLI DNSRNIAKDE FKAVKALVSS VIDNFNIASD
260 270 280 290 300
PLISDSGDRI ALLSYSPWES SRRKMGTVKT EFDFITYDNQ LLMKNHIQTS
310 320 330 340 350
FQQLNGEATI GRALLWTTEN LFPETPYLRK HKVIFVVSAG ENYERKEFVK
360 370 380 390 400
MMALRAKCQG YVIFVISLGS TRKDDMEELA SYPLDQHLIQ LGRIHKPDLN
410 420 430 440 450
YIAKFLKPFL YSVRRGFNQY PPPMLEDACR LINLGGENIQ NDGFQFVTEL
460 470 480 490 500
QEDFLGGNGF IGQELNSGRE SPFVKTEDNG SDYLVYLPSQ MFEPQKLMIN
510 520 530 540 550
YEKDQKSAEI ASLTSGHENY GRKEEPDHTY EPGDVSLQEY YMDVAFLIDA
560 570 580 590 600
SQRVGSDEFK EVKAFITSVL DYFHIAPTPL TSTLGDRVAV LSYSPPGYMP
610 620 630 640 650
NTEECPVYLE FDLVTYNSIH QMKHHLQDSQ QLNGDVFIGH ALQWTIDNVF
660 670 680 690 700
VGTPNLRKNK VIFVISAGET NSLDKDVLRN VSLRAKCQGY SIFVFSFGPK
710 720 730 740 750
HNDKELEELA SHPLDHHLVQ LGRTHKPDWN YIIKFVKPFV HLIRRAINKY
760 770
PTEDMKATCV NMTSPNPENG GTENTVLW
Length:778
Mass (Da):88,726
Last modified:February 22, 2012 - v1
Checksum:i9F1F8A838A96D165
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A8TX70CO6A5_HUMAN
Collagen alpha-5(VI) chain
COL6A5 COL29A1, VWA4
2,615Annotation score:
E9PAL5E9PAL5_HUMAN
Collagen alpha-5(VI) chain
COL6A5
2,611Annotation score:
H0Y393H0Y393_HUMAN
Collagen alpha-5(VI) chain
COL6A5
557Annotation score:
H0Y9T2H0Y9T2_HUMAN
Collagen alpha-5(VI) chain
COL6A5
443Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093004 Genomic DNA No translation available.
AC117398 Genomic DNA No translation available.
KF457678 Genomic DNA No translation available.
KF457681 Genomic DNA No translation available.
KF573676 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000512836; ENSP00000422898; ENSG00000172752
UCSCiuc062nty.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093004 Genomic DNA No translation available.
AC117398 Genomic DNA No translation available.
KF457678 Genomic DNA No translation available.
KF457681 Genomic DNA No translation available.
KF573676 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y935
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH0Y935
PRIDEiH0Y935

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000512836; ENSP00000422898; ENSG00000172752
UCSCiuc062nty.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000172752.14
HGNCiHGNC:26674 COL6A5
OpenTargetsiENSG00000172752
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3544 Eukaryota
ENOG410XNMM LUCA
GeneTreeiENSGT00760000119000

Gene expression databases

BgeeiENSG00000172752 Expressed in 38 organ(s), highest expression level in upper lobe of left lung
ExpressionAtlasiH0Y935 baseline and differential

Family and domain databases

Gene3Di3.40.50.410, 3 hits
InterProiView protein in InterPro
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF00092 VWA, 3 hits
SMARTiView protein in SMART
SM00327 VWA, 3 hits
SUPFAMiSSF53300 SSF53300, 3 hits
PROSITEiView protein in PROSITE
PS50234 VWFA, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y935_HUMAN
AccessioniPrimary (citable) accession number: H0Y935
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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