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Protein
Submitted name:

Calcium-dependent secretion activator 2

Gene

CADPS2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Calcium-dependent secretion activator 2Imported
Gene namesi
Name:CADPS2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000081803.15
HGNCiHGNC:16018 CADPS2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000081803

PTM / Processingi

Proteomic databases

MaxQBiH0Y8B5
PeptideAtlasiH0Y8B5
PRIDEiH0Y8B5

Expressioni

Gene expression databases

BgeeiENSG00000081803 Expressed in 197 organ(s), highest expression level in cerebellar vermis
ExpressionAtlasiH0Y8B5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y8B5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 250MHD1InterPro annotationAdd BLAST172

Phylogenomic databases

eggNOGiKOG3543 Eukaryota
ENOG410Y0FD LUCA
GeneTreeiENSGT00590000083094

Family and domain databases

InterProiView protein in InterPro
IPR033227 CAPS
IPR010439 CAPS_dom
IPR014770 Munc13_1
PANTHERiPTHR12166 PTHR12166, 1 hit
PfamiView protein in Pfam
PF06292 DUF1041, 1 hit
SMARTiView protein in SMART
SM01145 DUF1041, 1 hit
PROSITEiView protein in PROSITE
PS51258 MHD1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

H0Y8B5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XYTRLTEYAK IEGPAEKETE TMNQASPARK LEEILHLAEL CIEVLQQNEE
60 70 80 90 100
HHAEGREAFA WWPDLLAEHA EKFWALFTVD MDTALEAQPQ DSWDSFPLFQ
110 120 130 140 150
LLNNFLRNDT LLCNGKFHKH LQEIFVPLVV RYVDLMESSI AQSIHRGFEQ
160 170 180 190 200
ETWQPVKNIA NSLPNVALPK VPSLPLNLPQ IPNISTASWM PSLYESTNGS
210 220 230 240 250
ATSEDLFWKL DALQMFVFDL HWPEQEFAHH LEQRLKLMAS DMLEACVKRT
260 270 280 290 300
RTAFELKLQK ASKTTDLRIP ASVCTMFNVL VDAKKQSTKL CALDGGQEQQ
310 320 330 340 350
YHSKIDDLID NSVKEIISLL VSKFVSVLEG VLSKLSRYDE GTFFSSILSF
360 370 380 390 400
TVKAAAKYVD VPKPGMDLAD TYIMFVRQNQ DILREKVNEE MYIEKLFDQW
410 420 430 440 450
YSSSMKVICV WLTDRLDLQL HIYQLKTLIK IVKKTYRDFR LQGVLEGTLN
460 470 480 490
SKTYDTVHRR LTVEEATASV SEGGGLQGIT MKDSDEEEEG
Length:490
Mass (Da):56,168
Last modified:February 22, 2012 - v1
Checksum:i9FF7186F7C2F0D6F
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q86UW7CAPS2_HUMAN
Calcium-dependent secretion activat...
CADPS2 CAPS2, KIAA1591
1,296Annotation score:
C9IYE1C9IYE1_HUMAN
Calcium-dependent secretion activat...
CADPS2
1,294Annotation score:
A0A087X1P3A0A087X1P3_HUMAN
Calcium-dependent secretion activat...
CADPS2
1,301Annotation score:
F8W8P5F8W8P5_HUMAN
Calcium-dependent secretion activat...
CADPS2
1,194Annotation score:
H7BYR4H7BYR4_HUMAN
Calcium-dependent secretion activat...
CADPS2
899Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004594 Genomic DNA No translation available.
AC004986 Genomic DNA No translation available.
AC006009 Genomic DNA No translation available.
AC006463 Genomic DNA No translation available.
AC015983 Genomic DNA No translation available.
AC091438 Genomic DNA No translation available.
KF458579 Genomic DNA No translation available.
KF458587 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000462699; ENSP00000419418; ENSG00000081803
UCSCiuc064hnm.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004594 Genomic DNA No translation available.
AC004986 Genomic DNA No translation available.
AC006009 Genomic DNA No translation available.
AC006463 Genomic DNA No translation available.
AC015983 Genomic DNA No translation available.
AC091438 Genomic DNA No translation available.
KF458579 Genomic DNA No translation available.
KF458587 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y8B5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0Y8B5
PeptideAtlasiH0Y8B5
PRIDEiH0Y8B5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000462699; ENSP00000419418; ENSG00000081803
UCSCiuc064hnm.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000081803.15
HGNCiHGNC:16018 CADPS2
OpenTargetsiENSG00000081803
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3543 Eukaryota
ENOG410Y0FD LUCA
GeneTreeiENSGT00590000083094

Miscellaneous databases

ChiTaRSiCADPS2 human

Gene expression databases

BgeeiENSG00000081803 Expressed in 197 organ(s), highest expression level in cerebellar vermis
ExpressionAtlasiH0Y8B5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR033227 CAPS
IPR010439 CAPS_dom
IPR014770 Munc13_1
PANTHERiPTHR12166 PTHR12166, 1 hit
PfamiView protein in Pfam
PF06292 DUF1041, 1 hit
SMARTiView protein in SMART
SM01145 DUF1041, 1 hit
PROSITEiView protein in PROSITE
PS51258 MHD1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y8B5_HUMAN
AccessioniPrimary (citable) accession number: H0Y8B5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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