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Protein
Submitted name:

Amphiphysin

Gene

AMPH

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
AmphiphysinImported
Gene namesi
Name:AMPHImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000078053.16
HGNCiHGNC:471 AMPH

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000078053

PTM / Processingi

Proteomic databases

EPDiH0Y7T8
MaxQBiH0Y7T8
PeptideAtlasiH0Y7T8
PRIDEiH0Y7T8

Expressioni

Gene expression databases

BgeeiENSG00000078053 Expressed in 159 organ(s), highest expression level in middle temporal gyrus
ExpressionAtlasiH0Y7T8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y7T8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini505 – 578SH3InterPro annotationAdd BLAST74

Keywords - Domaini

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3771 Eukaryota
ENOG410ZBW1 LUCA
GeneTreeiENSGT00390000017588

Family and domain databases

CDDicd12140 SH3_Amphiphysin_I, 1 hit
InterProiView protein in InterPro
IPR003005 Amphiphysin
IPR003017 Amphiphysin_1
IPR035470 Amphiphysin_I_SH3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PANTHERiPTHR44669 PTHR44669, 3 hits
PfamiView protein in Pfam
PF14604 SH3_9, 1 hit
PRINTSiPR01251 AMPHIPHYSIN
PR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50002 SH3, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

H0Y7T8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XDSGPLRIAK TPSPPEEPSP LPSPTASPNH TLAPASPAPA RPRSPSQTRK
60 70 80 90 100
GPPVPPLPKV TPTKELQQEN IISFFEDNFV PEISVTTPSQ NEVPEVKKEE
110 120 130 140 150
TLLDLDFDPF KPEVTPAGSA GVTHSPMSQT LPWDLWTTST DLVQPTDSSE
160 170 180 190 200
SLSLCNLIME ETPDSGLAEE IQRSQNDIGA FTWGPDASTD RVSQEVTSGG
210 220 230 240 250
FGEDSACPSE TEQDIRLSTS LLSSADWPTV AEESEHAPGP AFPGGNEQLP
260 270 280 290 300
PKPAPEAGVA IAACVEMEQL YDPLDSDMPA MDTAGLFKES HEDMKKSDEE
310 320 330 340 350
EEKQKMEDSL WAGVEACQKA SGGSFNGFTQ PQDTSLFTMQ TDQSMICNLI
360 370 380 390 400
IPGADADAAV GTLVSAAEGA PGEEAEAEKA TVPAGEGVSL EEAKIGTETT
410 420 430 440 450
EGAESAQPEA EELEATVPQE KVIPSVVIEP ASNHEEEGEN EITIGAEPKE
460 470 480 490 500
TTEDAAPPGP TSETPELATE QKPIQDPQPT PSAPAMGAAD QLASAREASQ
510 520 530 540 550
ELPPGFLYKV ETLHDFEAAN SDELTLQRGD VVLVVPSDSE ADQDAGWLVG
560 570
VKESDWLQYR DLATYKGLFP ENFTRRLD
Length:578
Mass (Da):61,588
Last modified:February 22, 2012 - v1
Checksum:i39D5866E49835572
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P49418AMPH_HUMAN
Amphiphysin
AMPH AMPH1
695Annotation score:
H0Y5S4H0Y5S4_HUMAN
Amphiphysin
AMPH
112Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007245 Genomic DNA No translation available.
AC011309 Genomic DNA No translation available.
AC012490 Genomic DNA No translation available.
AC096581 Genomic DNA No translation available.
KF458445 Genomic DNA No translation available.
KF511030 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000441628; ENSP00000415085; ENSG00000078053
UCSCiuc064cye.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007245 Genomic DNA No translation available.
AC011309 Genomic DNA No translation available.
AC012490 Genomic DNA No translation available.
AC096581 Genomic DNA No translation available.
KF458445 Genomic DNA No translation available.
KF511030 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y7T8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH0Y7T8
MaxQBiH0Y7T8
PeptideAtlasiH0Y7T8
PRIDEiH0Y7T8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000441628; ENSP00000415085; ENSG00000078053
UCSCiuc064cye.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000078053.16
HGNCiHGNC:471 AMPH
OpenTargetsiENSG00000078053
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3771 Eukaryota
ENOG410ZBW1 LUCA
GeneTreeiENSGT00390000017588

Miscellaneous databases

ChiTaRSiAMPH human

Gene expression databases

BgeeiENSG00000078053 Expressed in 159 organ(s), highest expression level in middle temporal gyrus
ExpressionAtlasiH0Y7T8 baseline and differential

Family and domain databases

CDDicd12140 SH3_Amphiphysin_I, 1 hit
InterProiView protein in InterPro
IPR003005 Amphiphysin
IPR003017 Amphiphysin_1
IPR035470 Amphiphysin_I_SH3
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PANTHERiPTHR44669 PTHR44669, 3 hits
PfamiView protein in Pfam
PF14604 SH3_9, 1 hit
PRINTSiPR01251 AMPHIPHYSIN
PR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50002 SH3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y7T8_HUMAN
AccessioniPrimary (citable) accession number: H0Y7T8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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