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Protein
Submitted name:

Peroxisome proliferator-activated receptor gamma coactivator 1-beta

Gene

PPARGC1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Peroxisome proliferator-activated receptor gamma coactivator 1-betaImported
Gene namesi
Name:PPARGC1BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000155846.16
HGNCiHGNC:30022 PPARGC1B

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000155846

PTM / Processingi

Proteomic databases

MaxQBiH0Y713
PeptideAtlasiH0Y713
PRIDEiH0Y713

Expressioni

Gene expression databases

BgeeiENSG00000155846 Expressed in 166 organ(s), highest expression level in quadriceps femoris
ExpressionAtlasiH0Y713 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH0Y713
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini589 – 654RRMInterPro annotationAdd BLAST66

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili111 – 141Sequence analysisAdd BLAST31

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IIJJ Eukaryota
ENOG4111PZ5 LUCA
GeneTreeiENSGT00530000063196

Family and domain databases

CDDicd12356 RRM_PPARGC1B, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR034605 PGC-1
IPR034621 PGC-1beta
IPR034177 PPARGC1B_RRM
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PANTHERiPTHR15528 PTHR15528, 1 hit
PTHR15528:SF12 PTHR15528:SF12, 1 hit
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

H0Y713-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XACSNPSQQV RSRPWSRHHS KASWAEFSIL RELLAQDVLC DVSKPYRLAT
60 70 80 90 100
PVYASLTPRS RPRPPKDSQA SPGRPSSVEE VRIAASPKST GPRPSLRPLR
110 120 130 140 150
LEVKREVRRP ARLQQQEEED EEEEEEEEEE EKEEEEEWGR KRPGRGLPWT
160 170 180 190 200
KLGRKLESSV CPVRRSRRLN PELGPWLTFA DEPLVPSEPQ GALPSLCLAP
210 220 230 240 250
KAYDVERELG SPTDEDSGQD QQLLRGPQIP ALESPCESGC GDMDEDPSCP
260 270 280 290 300
QLPPRDSPRC LMLALSQSDP TFGKKSFEQT LTVELCGTAG LTPPTTPPYK
310 320 330 340 350
PTEEDPFKPD IKHSLGKEIA LSLPSPEGLS LKATPGAAHK LPKKHPERSE
360 370 380 390 400
LLSHLRHATA QPASQAGQKR PFSCSFGDHD YCQVLRPEGV LQRKVLRSWE
410 420 430 440 450
PSGVHLEDWP QQGAPWAEAQ APGREEDRSC DAGAPPKDST LLRDHEIRAS
460 470 480 490 500
LTKHFGLLET ALEEEDLASC KSPEYDTVFE DSSSSSGESS FLPEEEEEEG
510 520 530 540 550
EEEEEDDEEE DSGVSPTCSD HCPYQSPPSK ANRQLCSRSR SSSGSSPCHS
560 570 580 590 600
WSPATRRNFR CESRGPCSDR TPSIRHARKR REKAIGEGRV VYIQNLSSDM
610 620 630 640 650
SSRELKRRFE VFGEIEECEV LTRNRRGEKY GFITYRCSEH AALSLTKGAA
660 670 680 690 700
LRKRNEPSFQ LSYGGLRHFC WPRYTDYGWQ AVPTVQRSSQ LPKALGCSHS
710 720 730 740
TVPTHSGRFF NHPVFVSCSL PSPLPCLFTP MPRFQFRRGP SCVREKQV
Length:748
Mass (Da):83,838
Last modified:February 22, 2012 - v1
Checksum:i01406620DCE3AD2C
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q86YN6PRGC2_HUMAN
Peroxisome proliferator-activated r...
PPARGC1B PERC, PGC1, PGC1B, PPARGC1
1,023Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008545 Genomic DNA No translation available.
AC022100 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000434684; ENSP00000409364; ENSG00000155846
UCSCiuc063ipd.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008545 Genomic DNA No translation available.
AC022100 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y713
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0Y713
PeptideAtlasiH0Y713
PRIDEiH0Y713

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000434684; ENSP00000409364; ENSG00000155846
UCSCiuc063ipd.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000155846.16
HGNCiHGNC:30022 PPARGC1B
OpenTargetsiENSG00000155846
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IIJJ Eukaryota
ENOG4111PZ5 LUCA
GeneTreeiENSGT00530000063196

Miscellaneous databases

ChiTaRSiPPARGC1B human

Gene expression databases

BgeeiENSG00000155846 Expressed in 166 organ(s), highest expression level in quadriceps femoris
ExpressionAtlasiH0Y713 baseline and differential

Family and domain databases

CDDicd12356 RRM_PPARGC1B, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR034605 PGC-1
IPR034621 PGC-1beta
IPR034177 PPARGC1B_RRM
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PANTHERiPTHR15528 PTHR15528, 1 hit
PTHR15528:SF12 PTHR15528:SF12, 1 hit
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y713_HUMAN
AccessioniPrimary (citable) accession number: H0Y713
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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