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Protein
Submitted name:

Nucleoside diphosphate kinase, mitochondrial

Gene

NME4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Nucleoside diphosphate kinase, mitochondrialImported
Gene namesi
Name:NME4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000103202.12
HGNCiHGNC:7852 NME4

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000103202

PTM / Processingi

Proteomic databases

MaxQBiH0Y6J0
PeptideAtlasiH0Y6J0
PRIDEiH0Y6J0

Expressioni

Gene expression databases

BgeeiENSG00000103202 Expressed in 232 organ(s), highest expression level in fundus of stomach
ExpressionAtlasiH0Y6J0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y6J0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 157NDKInterPro annotationAdd BLAST125

Sequence similaritiesi

Belongs to the NDK family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119146

Family and domain databases

Gene3Di3.30.70.141, 1 hit
InterProiView protein in InterPro
IPR034907 NDK-like_dom
IPR036850 NDK-like_dom_sf
IPR001564 Nucleoside_diP_kinase
PfamiView protein in Pfam
PF00334 NDK, 1 hit
PRINTSiPR01243 NUCDPKINASE
SMARTiView protein in SMART
SM00562 NDK, 1 hit
SUPFAMiSSF54919 SSF54919, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

H0Y6J0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XWRSALRGLR CGPRAPGPSL LVRHGSGGPS WTRERTLVAV KPDGVQRRLV
60 70 80 90 100
GDVIQRFERR GFTLVGMKML QAPESVLAEH YQDLRRKPFY PALIRYMSSG
110 120 130 140 150
PVVAMVWEGY NVVRASRAMI GHTDSAEAAP GTIRGDFSVH ISSHRLAPLD
160
RGQREQQMVP GIPQGAHEA
Length:169
Mass (Da):18,713
Last modified:February 22, 2012 - v1
Checksum:i36A6D1A6BE015677
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O00746NDKM_HUMAN
Nucleoside diphosphate kinase, mito...
NME4 NM23D
187Annotation score:
Q4TT34Q4TT34_HUMAN
Nucleoside diphosphate kinase
NME4
195Annotation score:
F2Z2X0F2Z2X0_HUMAN
Nucleoside diphosphate kinase
NME4
233Annotation score:
A0A087WVT9A0A087WVT9_HUMAN
Nucleoside diphosphate kinase
NME4
153Annotation score:
A2IDC9A2IDC9_HUMAN
Nucleoside diphosphate kinase, mito...
NME4
37Annotation score:
F2Z297F2Z297_HUMAN
Nucleoside diphosphate kinase, mito...
NME4
44Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL023881 Genomic DNA No translation available.
Z97634 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000433358; ENSP00000405925; ENSG00000103202
UCSCiuc059ojz.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL023881 Genomic DNA No translation available.
Z97634 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y6J0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0Y6J0
PeptideAtlasiH0Y6J0
PRIDEiH0Y6J0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000433358; ENSP00000405925; ENSG00000103202
UCSCiuc059ojz.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000103202.12
HGNCiHGNC:7852 NME4
OpenTargetsiENSG00000103202
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000119146

Miscellaneous databases

ChiTaRSiNME4 human

Gene expression databases

BgeeiENSG00000103202 Expressed in 232 organ(s), highest expression level in fundus of stomach
ExpressionAtlasiH0Y6J0 baseline and differential

Family and domain databases

Gene3Di3.30.70.141, 1 hit
InterProiView protein in InterPro
IPR034907 NDK-like_dom
IPR036850 NDK-like_dom_sf
IPR001564 Nucleoside_diP_kinase
PfamiView protein in Pfam
PF00334 NDK, 1 hit
PRINTSiPR01243 NUCDPKINASE
SMARTiView protein in SMART
SM00562 NDK, 1 hit
SUPFAMiSSF54919 SSF54919, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y6J0_HUMAN
AccessioniPrimary (citable) accession number: H0Y6J0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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