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Protein
Submitted name:

Golgin subfamily A member 4

Gene

GOLGA4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Golgin subfamily A member 4Imported
Gene namesi
Name:GOLGA4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000144674.16
HGNCiHGNC:4427 GOLGA4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000144674

PTM / Processingi

Proteomic databases

EPDiH0Y6I0
MaxQBiH0Y6I0
PeptideAtlasiH0Y6I0
PRIDEiH0Y6I0

Expressioni

Gene expression databases

BgeeiENSG00000144674 Expressed in 240 organ(s), highest expression level in biceps brachii
ExpressionAtlasiH0Y6I0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y6I0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2039 – 2086GRIPInterPro annotationAdd BLAST48

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili7 – 27Sequence analysisAdd BLAST21
Coiled coili35 – 55Sequence analysisAdd BLAST21
Coiled coili60 – 80Sequence analysisAdd BLAST21
Coiled coili152 – 239Sequence analysisAdd BLAST88
Coiled coili241 – 282Sequence analysisAdd BLAST42
Coiled coili287 – 336Sequence analysisAdd BLAST50
Coiled coili342 – 377Sequence analysisAdd BLAST36
Coiled coili386 – 493Sequence analysisAdd BLAST108
Coiled coili499 – 533Sequence analysisAdd BLAST35
Coiled coili543 – 609Sequence analysisAdd BLAST67
Coiled coili611 – 670Sequence analysisAdd BLAST60
Coiled coili678 – 719Sequence analysisAdd BLAST42
Coiled coili724 – 765Sequence analysisAdd BLAST42
Coiled coili788 – 873Sequence analysisAdd BLAST86
Coiled coili908 – 957Sequence analysisAdd BLAST50
Coiled coili979 – 999Sequence analysisAdd BLAST21
Coiled coili1007 – 1055Sequence analysisAdd BLAST49
Coiled coili1135 – 1197Sequence analysisAdd BLAST63
Coiled coili1216 – 1253Sequence analysisAdd BLAST38
Coiled coili1260 – 1280Sequence analysisAdd BLAST21
Coiled coili1317 – 1432Sequence analysisAdd BLAST116
Coiled coili1437 – 1572Sequence analysisAdd BLAST136
Coiled coili1602 – 1629Sequence analysisAdd BLAST28
Coiled coili1699 – 1733Sequence analysisAdd BLAST35
Coiled coili1738 – 1758Sequence analysisAdd BLAST21
Coiled coili1789 – 1855Sequence analysisAdd BLAST67
Coiled coili1862 – 1968Sequence analysisAdd BLAST107
Coiled coili1990 – 2017Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IEA5 Eukaryota
ENOG410XQQG LUCA
GeneTreeiENSGT00730000111139

Family and domain databases

InterProiView protein in InterPro
IPR040071 GOLGA4
IPR000237 GRIP_dom
PANTHERiPTHR19327 PTHR19327, 2 hits
PfamiView protein in Pfam
PF01465 GRIP, 1 hit
SMARTiView protein in SMART
SM00755 Grip, 1 hit
PROSITEiView protein in PROSITE
PS50913 GRIP, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

H0Y6I0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
NSDSLNKEQL IQRLRRMERS LSSYRGKYSE LVTAYQMLQR EKKKLQGILS
60 70 80 90 100
QSQDKSLRRI AELREELQMD QQAKKHLQEE FDASLEEKDQ YISVLQTQVS
110 120 130 140 150
LLKQRLRNGP MNVDVLKPLP QLEPQAEVFT KEENPESDGE PVVEDGTSVK
160 170 180 190 200
TLETLQQRVK RQENLLKRCK ETIQSHKEQC TLLTSEKEAL QEQLDERLQE
210 220 230 240 250
LEKIKDLHMA EKTKLITQLR DAKNLIEQLE QDKGMVIAET KRQMHETLEM
260 270 280 290 300
KEEEIAQLRS RIKQMTTQGE ELREQKEKSE RAAFEELEKA LSTAQKTEEA
310 320 330 340 350
RRKLKAEMDE QIKTIEKTSE EERISLQQEL SRVKQEVVDV MKKSSEEQIA
360 370 380 390 400
KLQKLHEKEL ARKEQELTKK LQTREREFQE QMKVALEKSQ SEYLKISQEK
410 420 430 440 450
EQQESLALEE LELQKKAILT ESENKLRDLQ QEAETYRTRI LELESSLEKS
460 470 480 490 500
LQENKNQSKD LAVHLEAEKN KHNKEITVMV EKHKTELESL KHQQDALWTE
510 520 530 540 550
KLQVLKQQYQ TEMEKLREKC EQEKETLLKD KEIIFQAHIE EMNEKTLEKL
560 570 580 590 600
DVKQTELESL SSELSEVLKA RHKLEEELSV LKDQTDKMKQ ELEAKMDEQK
610 620 630 640 650
NHHQQQVDSI IKEHEVSIQR TEKALKDQIN QLELLLKERD KHLKEHQAHV
660 670 680 690 700
ENLEADIKRS EGELQQASAK LDVFQSYQSA THEQTKAYEE QLAQLQQKLL
710 720 730 740 750
DLETERILLT KQVAEVEAQK KDVCTELDAH KIQVQDLMQQ LEKQNSEMEQ
760 770 780 790 800
KVKSLTQVYE SKLEDGNKEQ EQTKQILVEK ENMILQMREG QKKEIEILTQ
810 820 830 840 850
KLSAKEDSIH ILNEEYETKF KNQEKKMEKV KQKAKEMQET LKKKLLDQEA
860 870 880 890 900
KLKKELENTA LELSQKEKQF NAKMLEMAQA NSAGISDAVS RLETNQKEQI
910 920 930 940 950
ESLTEVHRRE LNDVISIWEK KLNQQAEELQ EIHEIQLQEK EQEVAELKQK
960 970 980 990 1000
ILLFGCEKEE MNKEITWLKE EGVKQDTTLN ELQEQLKQKS AHVNSLAQDE
1010 1020 1030 1040 1050
TKLKAHLEKL EVDLNKSLKE NTFLQEQLVE LKMLAEEDKR KVSELTSKLK
1060 1070 1080 1090 1100
TTDEEFQSLK SSHEKSNKSL EDKSLEFKKL SEELAIQLDI CCKKTEALLE
1110 1120 1130 1140 1150
AKTNELINIS SSKTNAILSR ISHCQHRTTK VKEALLIKTC TVSELEAQLR
1160 1170 1180 1190 1200
QLTEEQNTLN ISFQQATHQL EEKENQIKSM KADIESLVTE KEALQKEGGN
1210 1220 1230 1240 1250
QQQAASEKES CITQLKKELS ENINAVTLMK EELKEKKVEI SSLSKQLTDL
1260 1270 1280 1290 1300
NVQLQNSISL SEKEAAISSL RKQYDEEKCE LLDQVQDLSF KVDTLSKEKI
1310 1320 1330 1340 1350
SALEQVDDWS NKFSEWKKKA QSRFTQHQNT VKELQIQLEL KSKEAYEKDE
1360 1370 1380 1390 1400
QINLLKEELD QQNKRFDCLK GEMEDDKSKM EKKESNLETE LKSQTARIME
1410 1420 1430 1440 1450
LEDHITQKTI EIESLNEVLK NYNQQKDIEH KELVQKLQHF QELGEEKDNR
1460 1470 1480 1490 1500
VKEAEEKILT LENQVYSMKA ELETKKKELE HVNLSVKSKE EELKALEDRL
1510 1520 1530 1540 1550
ESESAAKLAE LKRKAEQKIA AIKKQLLSQM EEKEEQYKKG TESHLSELNT
1560 1570 1580 1590 1600
KLQEREREVH ILEEKLKSVE SSQSETLIVP RSAKNVAAYT EQEEADSQGC
1610 1620 1630 1640 1650
VQKTYEEKIS VLQRNLTEKE KLLQRVGQEK EETVSSHFEM RCQYQERLIK
1660 1670 1680 1690 1700
LEHAEAKQHE DQSMIGHLQE ELEEKNKKYS LIVAQHVEKE GGKNNIQAKQ
1710 1720 1730 1740 1750
NLENVFDDVQ KTLQEKELTC QILEQKIKEL DSCLVRQKEV HRVEMEELTS
1760 1770 1780 1790 1800
KYEKLQALQQ MDGRNKPTEL LEENTEEKSK SHLVQPKLLS NMEAQHNDLE
1810 1820 1830 1840 1850
FKLAGAEREK QKLGKEIVRL QKDLRMLRKE HQQELEILKK EYDQEREEKI
1860 1870 1880 1890 1900
KQEQEDLELK HNSTLKQLMR EFNTQLAQKE QELEMTIKET INKAQEVEAE
1910 1920 1930 1940 1950
LLESHQEETN QLLKKIAEKD DDLKRTAKRY EEILDAREEE MTAKVRDLQT
1960 1970 1980 1990 2000
QLEELQKKYQ QKLEQEENPG NDNVTIMELQ TQLAQKTTLI SDSKLKEQEF
2010 2020 2030 2040 2050
REQIHNLEDR LKKYEKNVYA TTVGTPYKGG NLYHTDVSLF GEPTEFEYLR
2060 2070 2080 2090
KVLFEYMMGR ETKTMAKVIT TVLKFPDDQT QKILEREDAR LMSWLRSSS
Length:2,099
Mass (Da):246,607
Last modified:February 22, 2012 - v1
Checksum:iFD95F45A2917ED39
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q13439GOGA4_HUMAN
Golgin subfamily A member 4
GOLGA4
2,230Annotation score:
E7EVX2E7EVX2_HUMAN
Golgin subfamily A member 4
GOLGA4
445Annotation score:
C9JHJ5C9JHJ5_HUMAN
Golgin subfamily A member 4
GOLGA4
585Annotation score:
A0A087WTW2A0A087WTW2_HUMAN
Golgin subfamily A member 4
GOLGA4
218Annotation score:
Q86W71Q86W71_HUMAN
GOLGA4 protein
GOLGA4
166Annotation score:
C9J0Y3C9J0Y3_HUMAN
Golgin subfamily A member 4
GOLGA4
118Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097359 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000437131; ENSP00000405842; ENSG00000144674
UCSCiuc062icv.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC097359 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y6I0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH0Y6I0
MaxQBiH0Y6I0
PeptideAtlasiH0Y6I0
PRIDEiH0Y6I0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000437131; ENSP00000405842; ENSG00000144674
UCSCiuc062icv.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000144674.16
HGNCiHGNC:4427 GOLGA4
OpenTargetsiENSG00000144674
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IEA5 Eukaryota
ENOG410XQQG LUCA
GeneTreeiENSGT00730000111139

Miscellaneous databases

ChiTaRSiGOLGA4 human

Gene expression databases

BgeeiENSG00000144674 Expressed in 240 organ(s), highest expression level in biceps brachii
ExpressionAtlasiH0Y6I0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR040071 GOLGA4
IPR000237 GRIP_dom
PANTHERiPTHR19327 PTHR19327, 2 hits
PfamiView protein in Pfam
PF01465 GRIP, 1 hit
SMARTiView protein in SMART
SM00755 Grip, 1 hit
PROSITEiView protein in PROSITE
PS50913 GRIP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y6I0_HUMAN
AccessioniPrimary (citable) accession number: H0Y6I0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: November 7, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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