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Protein
Submitted name:

CLIP-associating protein 1

Gene

CLASP1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
CLIP-associating protein 1Imported
Gene namesi
Name:CLASP1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000074054.17
HGNCiHGNC:17088 CLASP1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000074054

PTM / Processingi

Proteomic databases

PeptideAtlasiH0Y5T1
PRIDEiH0Y5T1

Expressioni

Gene expression databases

BgeeiENSG00000074054
ExpressionAtlasiH0Y5T1 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliH0Y5T1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini100 – 332TOGInterPro annotationAdd BLAST233
Domaini1026 – 1264TOGInterPro annotationAdd BLAST239

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1045 – 1065Sequence analysisAdd BLAST21
Coiled coili1127 – 1147Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000001762

Family and domain databases

Gene3Di1.25.10.10, 4 hits
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR028399 CLASP_1
IPR024395 CLASP_N_dom
IPR034085 TOG
PANTHERiPTHR21567:SF28 PTHR21567:SF28, 1 hit
PfamiView protein in Pfam
PF12348 CLASP_N, 1 hit
SMARTiView protein in SMART
SM01349 TOG, 2 hits
SUPFAMiSSF48371 SSF48371, 3 hits

Sequencei

Sequence statusi: Fragment.

H0Y5T1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
XTKFDEVQKS GNMIQSANDK NFDDEDSVDG NRPSSASSTS SKAPPSSRRN
60 70 80 90 100
VGMGTTRRLG SSTLGSKSSA AKEGAGAVDE EDFIKAFDDV PVVQIYSSRD
110 120 130 140 150
LEESINKIRE ILSDDKHDWE QRVNALKKIR SLLLAGAAEY DNFFQHLRLL
160 170 180 190 200
DGAFKLSAKD LRSQVVREAC ITLGHLSSVL GNKFDHGAEA IMPTIFNLIP
210 220 230 240 250
NSAKIMATSG VVAVRLIIRH THIPRLIPVI TSNCTSKSVA VRRRCFEFLD
260 270 280 290 300
LLLQEWQTHS LERHISVLAE TIKKGIHDAD SEARIEARKC YWGFHSHFSR
310 320 330 340 350
EAEHLYHTLE SSYQKALQSH LKNSDSIVSL PQSDRSSSSS QESLNRPLSA
360 370 380 390 400
KRSPTGSTTS RASTVSTKSV STTGSLQRSR SDIDVNAAAS AKSKVSSSSG
410 420 430 440 450
TTPFSSAAAL PPGSYASLGR IRTRRQSSGS ATNVASTPDN RGRSRAKVVS
460 470 480 490 500
QSQRSRSANP AGAGSRSSSP GKLLGSGYGG LTGGSSRGPP VTPSSEKRSK
510 520 530 540 550
IPRSQGCSRE TSPNRIGLDR FGLGQPGRIP GSVNAMRVLS TSTDLEAAVA
560 570 580 590 600
DALLLGDSRS KKKPVRRRYE PYGMYSDDDA NSDASSVCSE RSYGSRNGGI
610 620 630 640 650
PHYLRQTEDV AEVLNHCASS NWSERKEGLL GLQNLLKSQR TLSRVELKRL
660 670 680 690 700
CEIFTRMFAD PHSKIADSEA ECEDKEGNLF PSEVSCTRVF SMFLETLVDF
710 720 730 740 750
IIIHKDDLQD WLFVLLTQLL KKMGADLLGS VQAKVQKALD VTRDSFPFDQ
760 770 780 790 800
QFNILMRFIV DQTQTPNLKV KVAILKYIES LARQMDPTDF VNSSETRLAV
810 820 830 840 850
SRIITWTTEP KSSDVRKAAQ IVLISLFELN TPEFTMLLGA LPKTFQDGAT
860 870 880 890 900
KLLHNHLKNS SNTSVGSPSN TIGRTPSRHT SSRTSPLTSP TNCSHGGLSP
910 920 930 940 950
SMLDYDTENL NSEEIYSSLR GVTEAIEKFS FRSQEDLNEP IKRDGKKECD
960 970 980 990 1000
IVSRDGGAAS PATEGRGGSE VEGGRTALDN KTSLLNTQPP RAFPGPRARD
1010 1020 1030 1040 1050
YNPYPYSDAI NTYDKTALKE AVFDDDMEQL RDVPIDHSDL VADLLKELSN
1060 1070 1080 1090 1100
HNERVEERKG ALLELLKITR EDSLGVWEEH FKTILLLLLE TLGDKDHSIR
1110 1120 1130 1140 1150
ALALRVLREI LRNQPARFKN YAELTIMKTL EAHKDSHKEV VRAAEEAAST
1160 1170 1180 1190 1200
LASSIHPEQC IKVLCPIIQT ADYPINLAAI KMQTKVVERI AKESLLQLLV
1210 1220 1230 1240 1250
DIIPGLLQGY DNTESSVRKA SVFCLVAIYS VIGEDLKPHL AQLTGSKMKL
1260 1270
LNLYIKRAQT TNSNSSSSSD VSTHS
Length:1,275
Mass (Da):140,047
Last modified:May 27, 2015 - v2
Checksum:i8B3D0CFE14B8B73E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012447 Genomic DNA No translation available.
AC013399 Genomic DNA No translation available.
AC018737 Genomic DNA No translation available.
AC079449 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000452274; ENSP00000400562; ENSG00000074054
UCSCiuc061nlj.1 human

Similar proteinsi

Entry informationi

Entry nameiH0Y5T1_HUMAN
AccessioniPrimary (citable) accession number: H0Y5T1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: May 27, 2015
Last modified: June 20, 2018
This is version 52 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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