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Protein
Submitted name:

Centrosome-associated protein CEP250

Gene

CEP250

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Centrosome-associated protein CEP250Imported
Gene namesi
Name:CEP250Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000126001.15
HGNCiHGNC:1859 CEP250

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000126001

PTM / Processingi

Proteomic databases

MaxQBiH0Y5R2
PeptideAtlasiH0Y5R2
PRIDEiH0Y5R2

Expressioni

Gene expression databases

BgeeiENSG00000126001 Expressed in 150 organ(s), highest expression level in testis
ExpressionAtlasiH0Y5R2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y5R2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili84 – 104Sequence analysisAdd BLAST21
Coiled coili119 – 209Sequence analysisAdd BLAST91

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IFAN Eukaryota
ENOG410XPG3 LUCA
GeneTreeiENSGT00730000110800

Family and domain databases

InterProiView protein in InterPro
IPR026048 CEP250
PANTHERiPTHR23159:SF1 PTHR23159:SF1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

H0Y5R2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XGGTAGGAAP GCPGEGASGC WEDESNVLEN ASIEPGICQE MLMGLEAKQS
60 70 80 90 100
ESLSELITLR EALESSHLEG ELLRQEQTEV TAALARAEQS IAELSSSENT
110 120 130 140 150
LKTEVADLRA AAVKLSALNE ALALDKVGLN QQLLQLEEEN QSVCSRMEAA
160 170 180 190 200
EQARNALQVD LAEAEKRREA LWEKNTHLEA QLQKAEEAGA ELQADLRDIQ
210
EEKEEIQKKL
Length:210
Mass (Da):22,718
Last modified:February 22, 2012 - v1
Checksum:i3D58AF692D4D70E2
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9BV73CP250_HUMAN
Centrosome-associated protein CEP25...
CEP250 CEP2, CNAP1
2,442Annotation score:
H7C0P0H7C0P0_HUMAN
Centrosome-associated protein CEP25...
CEP250
877Annotation score:
A6PVI9A6PVI9_HUMAN
Centrosomal protein 250kDa
CEP250 RP3-477O4.2-006
339Annotation score:
Q5JWS5Q5JWS5_HUMAN
Centrosomal protein 250kDa
CEP250 RP3-477O4.2-002
164Annotation score:
E7ETF9E7ETF9_HUMAN
Centrosome-associated protein CEP25...
CEP250
684Annotation score:
E9PHT2E9PHT2_HUMAN
Centrosome-associated protein CEP25...
CEP250
538Annotation score:
H7C0D6H7C0D6_HUMAN
Centrosome-associated protein CEP25...
CEP250
138Annotation score:
Q5JWS6Q5JWS6_HUMAN
Centrosomal protein 250kDa
CEP250 RP3-477O4.2-003
114Annotation score:
A0A087WZ34A0A087WZ34_HUMAN
Centrosome-associated protein CEP25...
CEP250
34Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei210Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO393401 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000425096; ENSP00000400200; ENSG00000126001
UCSCiuc061wmr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO393401 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y5R2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0Y5R2
PeptideAtlasiH0Y5R2
PRIDEiH0Y5R2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000425096; ENSP00000400200; ENSG00000126001
UCSCiuc061wmr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000126001.15
HGNCiHGNC:1859 CEP250
OpenTargetsiENSG00000126001
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFAN Eukaryota
ENOG410XPG3 LUCA
GeneTreeiENSGT00730000110800

Miscellaneous databases

ChiTaRSiCEP250 human

Gene expression databases

BgeeiENSG00000126001 Expressed in 150 organ(s), highest expression level in testis
ExpressionAtlasiH0Y5R2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR026048 CEP250
PANTHERiPTHR23159:SF1 PTHR23159:SF1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y5R2_HUMAN
AccessioniPrimary (citable) accession number: H0Y5R2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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