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Protein
Submitted name:

Serpin B4

Gene

SERPINB4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Serpin B4Imported
Gene namesi
Name:SERPINB4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 18

Organism-specific databases

EuPathDBiHostDB:ENSG00000206073.10
HGNCiHGNC:10570 SERPINB4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000206073

PTM / Processingi

Proteomic databases

PeptideAtlasiH0Y5H9
PRIDEiH0Y5H9

Expressioni

Gene expression databases

BgeeiENSG00000206073 Expressed in 48 organ(s), highest expression level in ectocervix
ExpressionAtlasiH0Y5H9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y5H9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 371SERPINInterPro annotationAdd BLAST357

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118789

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 2 hits
PfamiView protein in Pfam
PF00079 Serpin, 2 hits
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

H0Y5H9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XTMNSLSEAN TKFMFDLFQQ FRKSKENNIF YSPISITSAL GMVLLGAKDN
60 70 80 90 100
TAQQISKVLH FDQVTENTTE KAATYHVDRS GNVHHQFQKL LTEFNKSTDA
110 120 130 140 150
YELKIANKLF GEKTYQFLQE YLDAIKKFYQ TSVESTDFAN APEESRKKIN
160 170 180 190 200
SWVESQTNEK IKNLFPDGTI GNDTTLVLVN AIYFKGQWEN KFKKENTKEE
210 220 230 240 250
KFWPNKDVQA KVLEIPYKGK DLSMIVLLPN EIDGLQKLEE KLTAEKLMEW
260 270 280 290 300
TSLQNMRETC VDLHLPRFKM EESYDLKDTL RTMGMVNIFN GDADLSGMTW
310 320 330 340 350
SHGLSVSKVL HKAFVEVTEE GVEAAAATAV VVVELSSPST NEEFCCNHPF
360 370
LFFIRQNKTN SILFYGRFSS P
Length:371
Mass (Da):42,499
Last modified:February 22, 2012 - v1
Checksum:iDF60C2E0600E1B64
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P48594SPB4_HUMAN
Serpin B4
SERPINB4 PI11, SCCA2
390Annotation score:
C9JZ65C9JZ65_HUMAN
Serpin B4
SERPINB4
211Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC069356 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000413673; ENSP00000398645; ENSG00000206073
UCSCiuc060pvv.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC069356 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y5H9
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH0Y5H9
PRIDEiH0Y5H9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000413673; ENSP00000398645; ENSG00000206073
UCSCiuc060pvv.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000206073.10
HGNCiHGNC:10570 SERPINB4
OpenTargetsiENSG00000206073
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118789

Miscellaneous databases

ChiTaRSiSERPINB4 human

Gene expression databases

BgeeiENSG00000206073 Expressed in 48 organ(s), highest expression level in ectocervix
ExpressionAtlasiH0Y5H9 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 2 hits
PfamiView protein in Pfam
PF00079 Serpin, 2 hits
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y5H9_HUMAN
AccessioniPrimary (citable) accession number: H0Y5H9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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