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Entry version 38 (08 May 2019)
Sequence version 1 (22 Feb 2012)
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Protein
Submitted name:

Neuroblastoma-amplified sequence

Gene

NBAS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Neuroblastoma-amplified sequenceImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NBASImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:15625 NBAS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000151779

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
H0Y5G7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
H0Y5G7

PeptideAtlas

More...
PeptideAtlasi
H0Y5G7

PRoteomics IDEntifications database

More...
PRIDEi
H0Y5G7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000151779 Expressed in 226 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
H0Y5G7 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini68 – 413Sec39InterPro annotationAdd BLAST346

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1797 Eukaryota
ENOG410YJNG LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012474

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR013244 Sec39_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08314 Sec39, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

H0Y5G7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XMTQLTVEKV MDWYQTRAEE IEHYARQLQQ KIIPDQDQLM AIALECIYTC
60 70 80 90 100
ERNDQLCLCY DLLECLPERG YGDKTEATTK LHDMVDQLEQ ILSVSELLEK
110 120 130 140 150
HGLEKPISFV KNTQSSSEEA RKLMVRLTRH TGRKQPPVSE SHWRTLLQDM
160 170 180 190 200
LTMQQNVYTC LDSDACYEIF TESLLCSSRL ENIHLAGQMM HCSACSENPP
210 220 230 240 250
AGIAHKGKPH YRVSYEKSID LVLAASREYF NSSTNLTDSC MDLARCCLQL
260 270 280 290 300
ITDRPPAIQE ELDLIQAVGC LEEFGVKILP LQVRLCPDRI SLIKECISQS
310 320 330 340 350
PTCYKQSTKL LGLAELLRVA GENPEERRGQ VLILLVEQAL RFHDYKAASM
360 370 380 390 400
HCQELMATGY PKSWDVCSQL GQSEGYQDLA TRQELMAFAL THCPPSSIEL
410 420 430 440 450
LLAASSSLQT EILYQRVNFQ IHHEGGENIS ASPLTSKAVQ EDEVGVPGSN
460 470 480 490 500
SADLLRWTTA TTMKVLSNTT TTTKAVLQAV SDGQWWKKSL TYLRPLQGQK
510 520 530 540 550
CGGAYQIGTT ANEDLEKQGC HPFYESVISN PFVAESEGTY DTYQHVPVES
560 570 580 590 600
FAEVLLRTGK LAEAKNKGEV FPTTEVLLQL ASEALPNDMT LALAYLLALP
610 620 630 640 650
QVLDANRCFE KQSPSALSLQ LAAYYYSLQI YARLAPCFRD KCHPLYRADP
660 670 680 690 700
KELIKMVTRH VTRHEHEAWP EDLISLTKQL HCYNERLLDF TQAQILQGLR
710 720 730 740 750
KGVDVQRFTA DDQYKRETIL GLAETLEESV YSIAISLAQR YSVSRWEVFM
760 770 780 790 800
THLEFLFTDS GLSTLEIENR AQDLHLFETL KTDPEAFHQH MVKYIYPTIG
810 820 830 840 850
GFDHERLQYY FTLLENCGCA DLGNCAIKPE THIRLLKKFK VVASGLNYKK
860 870 880 890 900
LTDENMSPLE ALEPVLSSQN ILSISKLVPK IPEKDGQMLS PSSLYTIWLQ
910 920 930 940 950
KLFWTGDPHL IKQVPGSSPE WLHAYDVCMK YFDRLHPGDL ITVVDAVTFS
960 970 980 990 1000
PKAVTKLSVE ARKEMTRKAI KTVKHFIEKP RKRNSEDEAQ EAKDSKVTYA
1010 1020 1030 1040 1050
DTLNHLEKSL AHLETLSHSF ILSLKNSEQE TLQKYSHLYD LSRSEKEKLH
1060 1070 1080 1090 1100
DEAVAICLDG QPLAMIQQLL EVAVGPLDIS PKDIVQSAIM KIISALSGGS
1110 1120 1130 1140 1150
ADLGGPRDPL KVLEGVVAAV HASVDKGEEL VSPEDLLEWL RPFCADDAWP
1160 1170 1180 1190 1200
VRPRIHVLQI LGQSFHLTEE DSKLLVFFRT EAILKASWPQ RQVDIADIEN
1210 1220 1230 1240 1250
EENRYCLFME LLESSHHEAE FQHLVLLLQA WPPMKSEYVI TNNPWVRLAT
1260 1270 1280 1290 1300
VMLTRCTMEN KEGLGNEVLK MCRSLYNTKQ MLPAEGVKEL CLLLLNQSLL
1310 1320 1330 1340 1350
LPSLKLLLES RDEHLHEMAL EQITAVTTVN DSNCDQELLS LLLDAKLLVK
1360 1370 1380 1390 1400
CVSTPFYPRI VDHLLASLQQ GRWDAEELGR HLREAGHEAE AGSLLLAVRG
1410
THQAFRTFST ALRAAQHWV
Length:1,419
Mass (Da):160,528
Last modified:February 22, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i01D76546A9B7C87E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A2RRP1NBAS_HUMAN
Neuroblastoma-amplified sequence
NBAS NAG
2,371Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7BZU5H7BZU5_HUMAN
Neuroblastoma-amplified sequence
NBAS
204Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JCM7C9JCM7_HUMAN
Neuroblastoma-amplified sequence
NBAS
281Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C1U4H7C1U4_HUMAN
Neuroblastoma-amplified sequence
NBAS
100Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7BZR3H7BZR3_HUMAN
Neuroblastoma-amplified sequence
NBAS
184Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C1Y9H7C1Y9_HUMAN
Neuroblastoma-amplified sequence
NBAS
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C007H7C007_HUMAN
Neuroblastoma-amplified sequence
NBAS
171Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC007738 Genomic DNA No translation available.
AC008278 Genomic DNA No translation available.
AC008282 Genomic DNA No translation available.
AC074184 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000442506; ENSP00000398411; ENSG00000151779

UCSC genome browser

More...
UCSCi
uc061gur.1 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007738 Genomic DNA No translation available.
AC008278 Genomic DNA No translation available.
AC008282 Genomic DNA No translation available.
AC074184 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Proteomic databases

jPOSTiH0Y5G7
MaxQBiH0Y5G7
PeptideAtlasiH0Y5G7
PRIDEiH0Y5G7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000442506; ENSP00000398411; ENSG00000151779
UCSCiuc061gur.1 human

Organism-specific databases

HGNCiHGNC:15625 NBAS
OpenTargetsiENSG00000151779

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1797 Eukaryota
ENOG410YJNG LUCA
GeneTreeiENSGT00390000012474

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
NBAS human

Gene expression databases

BgeeiENSG00000151779 Expressed in 226 organ(s), highest expression level in corpus callosum
ExpressionAtlasiH0Y5G7 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR013244 Sec39_domain
PfamiView protein in Pfam
PF08314 Sec39, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH0Y5G7_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H0Y5G7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 8, 2019
This is version 38 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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