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Protein
Submitted name:

Cip1-interacting zinc finger protein

Gene

CIZ1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Cip1-interacting zinc finger proteinImported
Gene namesi
Name:CIZ1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000148337.20
HGNCiHGNC:16744 CIZ1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000148337

PTM / Processingi

Proteomic databases

EPDiH0Y5D5
PeptideAtlasiH0Y5D5
PRIDEiH0Y5D5

Expressioni

Gene expression databases

BgeeiENSG00000148337 Expressed in 229 organ(s), highest expression level in testis
ExpressionAtlasiH0Y5D5 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y5D5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini721 – 752Matrin-typeInterPro annotationAdd BLAST32

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili631 – 651Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiENOG410II97 Eukaryota
ENOG4111HAM LUCA
GeneTreeiENSGT00440000039084

Family and domain databases

InterProiView protein in InterPro
IPR026811 CIZ1
IPR000690 Matrin/U1-C_Znf_C2H2
IPR003604 Matrin/U1-like-C_Znf_C2H2
IPR022755 Znf_C2H2_jaz
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR15491 PTHR15491, 2 hits
PfamiView protein in Pfam
PF12171 zf-C2H2_jaz, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SM00451 ZnF_U1, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS50171 ZF_MATRIN, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

H0Y5D5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
PLPMAVSRGL PPQQPQQPLL NLQGTNSASL LNGSMLQRAL LLQQLQGNLR
60 70 80 90 100
GYGMASPGLA APSLTPPQLA TPNLQQFFPQ ATRQSLLGPP PVGVPMNPSQ
110 120 130 140 150
FNLSGRNPQK QARTSSSTTP NRKTMPVEDK SDPPEGSEEA AEPRMDTPED
160 170 180 190 200
QDLPPCPEDI AKEKRTPAPE PEPCEASELP AKRLRSSEEP TEKEPPGQLQ
210 220 230 240 250
VKAQPQARMT VPKQTQTPDL LPEALEAQVL PRFQPRVLQV QAQVQSQTQP
260 270 280 290 300
RIPSTDTQVQ PKLQKQAQTQ TSPEHLVLQQ KQVQPQLQQE AEPQKQVQPQ
310 320 330 340 350
VQPQAHSQGP RQVQLQQEAE PLKQVQPQVQ PQAHSQPPRQ VQLQLQKQVQ
360 370 380 390 400
TQTYPQVHTQ AQPSVQPQEH PPAQVSVQPP EQTHEQPHTQ PQVSLLAPEQ
410 420 430 440 450
TPVVVHVCGL EMPPDAVEAG GGMEKTLPEP VGTQVSMEEI QNESACGLDV
460 470 480 490 500
GECENRAREM PGVWGAGGSL KVTILQSSDS RAFSTVPLTP VPRPSDSVSS
510 520 530 540 550
TPAATSTPSK QALQFFCYIC KASCSSQQEF QDHMSEPQHQ QRLGEIQHMS
560 570 580 590 600
QACLLSLLPV PRDVLETEDE EPPPRRWCNT CQLYYMGDLI QHRRTQDHKI
610 620 630 640 650
AKQSLRPFCT VCNRYFKTPR KFVEHVKSQG HKDKAKELKS LEKEIAGQDE
660 670 680 690 700
DHFITVDAVG CFEGDEEEEE DDEDEEEIEV EEELCKQVRS RDISREEWKG
710 720 730 740 750
SETYSPNTAY GVDFLVPVMG YICRICHKFY HSNSGAQLSH CKSLGHFENL
760 770 780 790 800
QKYKAAKNPS PTTRPVSRRC AINARNALTA LFTSSGRPPS QPNTQDKTPS
810 820
KVTARPSQPP LPRRSTRLKT
Length:820
Mass (Da):91,125
Last modified:February 22, 2012 - v1
Checksum:iFA2E9094E80AA611
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9ULV3CIZ1_HUMAN
Cip1-interacting zinc finger protei...
CIZ1 LSFR1, NP94, ZNF356
898Annotation score:
F5H2X7F5H2X7_HUMAN
Cip1-interacting zinc finger protei...
CIZ1
954Annotation score:
Q9BTG3Q9BTG3_HUMAN
CIZ1 protein
CIZ1
837Annotation score:
Q5SYW2Q5SYW2_HUMAN
Cip1-interacting zinc finger protei...
CIZ1
870Annotation score:
A0A0U1RQR2A0A0U1RQR2_HUMAN
Cip1-interacting zinc finger protei...
CIZ1
310Annotation score:
F6VD24F6VD24_HUMAN
Cip1-interacting zinc finger protei...
CIZ1
252Annotation score:
F6WSM2F6WSM2_HUMAN
Cip1-interacting zinc finger protei...
CIZ1
168Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590708 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000415526; ENSP00000398011; ENSG00000148337
UCSCiuc064wbr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590708 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y5D5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiH0Y5D5
PeptideAtlasiH0Y5D5
PRIDEiH0Y5D5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000415526; ENSP00000398011; ENSG00000148337
UCSCiuc064wbr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000148337.20
HGNCiHGNC:16744 CIZ1
OpenTargetsiENSG00000148337
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410II97 Eukaryota
ENOG4111HAM LUCA
GeneTreeiENSGT00440000039084

Miscellaneous databases

ChiTaRSiCIZ1 human

Gene expression databases

BgeeiENSG00000148337 Expressed in 229 organ(s), highest expression level in testis
ExpressionAtlasiH0Y5D5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR026811 CIZ1
IPR000690 Matrin/U1-C_Znf_C2H2
IPR003604 Matrin/U1-like-C_Znf_C2H2
IPR022755 Znf_C2H2_jaz
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR15491 PTHR15491, 2 hits
PfamiView protein in Pfam
PF12171 zf-C2H2_jaz, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SM00451 ZnF_U1, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS50171 ZF_MATRIN, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y5D5_HUMAN
AccessioniPrimary (citable) accession number: H0Y5D5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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