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Protein
Submitted name:

LIM and senescent cell antigen-like-containing domain protein 2

Gene

LIMS2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
LIM and senescent cell antigen-like-containing domain protein 2Imported
Gene namesi
Name:LIMS2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000072163.18
HGNCiHGNC:16084 LIMS2

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000072163

PTM / Processingi

Proteomic databases

MaxQBiH0Y592
PeptideAtlasiH0Y592
PRIDEiH0Y592

Expressioni

Gene expression databases

BgeeiENSG00000072163 Expressed in 190 organ(s), highest expression level in fundus of stomach
ExpressionAtlasiH0Y592 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y592
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 82LIM zinc-bindingInterPro annotationAdd BLAST79
Domaini83 – 143LIM zinc-bindingInterPro annotationAdd BLAST61

Keywords - Domaini

LIM domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118910

Family and domain databases

InterProiView protein in InterPro
IPR017351 PINCH
IPR001781 Znf_LIM
PANTHERiPTHR24210 PTHR24210, 2 hits
PfamiView protein in Pfam
PF00412 LIM, 2 hits
SMARTiView protein in SMART
SM00132 LIM, 2 hits
PROSITEiView protein in PROSITE
PS50023 LIM_DOMAIN_2, 2 hits

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

H0Y592-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XGVPICGACR RPIEGRVVNA LGKQWHVEVS QAGGHVASGW GVPQLRVMHF
60 70 80 90 100
VCAKCEKPFL GHRHYEKKGL AYCETHYNQL FGDVCYNCSH VIEGDVVSAL
110 120 130 140 150
NKAWCVSCFS CSTCNSKLTL KNKFVEFDMK PVCKRCYEKF PLELKKRLKK
160
LSELTSRKAQ PKATDLNSA
Length:169
Mass (Da):18,964
Last modified:February 22, 2012 - v1
Checksum:i65D96D21FFDC983C
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q7Z4I7LIMS2_HUMAN
LIM and senescent cell antigen-like...
LIMS2 PINCH2
341Annotation score:
F8WEF3F8WEF3_HUMAN
LIM and senescent cell antigen-like...
LIMS2
60Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010976 Genomic DNA No translation available.
AC074114 Genomic DNA No translation available.
KF510755 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000426981; ENSP00000397253; ENSG00000072163
UCSCiuc061nqk.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010976 Genomic DNA No translation available.
AC074114 Genomic DNA No translation available.
KF510755 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y592
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0Y592
PeptideAtlasiH0Y592
PRIDEiH0Y592

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000426981; ENSP00000397253; ENSG00000072163
UCSCiuc061nqk.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000072163.18
HGNCiHGNC:16084 LIMS2
OpenTargetsiENSG00000072163
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118910

Miscellaneous databases

ChiTaRSiLIMS2 human

Gene expression databases

BgeeiENSG00000072163 Expressed in 190 organ(s), highest expression level in fundus of stomach
ExpressionAtlasiH0Y592 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR017351 PINCH
IPR001781 Znf_LIM
PANTHERiPTHR24210 PTHR24210, 2 hits
PfamiView protein in Pfam
PF00412 LIM, 2 hits
SMARTiView protein in SMART
SM00132 LIM, 2 hits
PROSITEiView protein in PROSITE
PS50023 LIM_DOMAIN_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y592_HUMAN
AccessioniPrimary (citable) accession number: H0Y592
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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