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Protein
Submitted name:

Dynein regulatory complex protein 8

Gene

EFCAB2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Dynein regulatory complex protein 8Imported
Gene namesi
Name:EFCAB2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000203666.12
HGNCiHGNC:28166 EFCAB2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000203666

PTM / Processingi

Proteomic databases

PeptideAtlasiH0Y588

Expressioni

Gene expression databases

BgeeiENSG00000203666 Expressed in 209 organ(s), highest expression level in right uterine tube
ExpressionAtlasiH0Y588 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y588
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 35EF-handInterPro annotationAdd BLAST35

Phylogenomic databases

eggNOGiKOG0027 Eukaryota
COG5126 LUCA
GeneTreeiENSGT00670000097718

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

H0Y588-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XEDVLLRAFE VLDSAKRGFL TKDELIKYMT EEGGVVITPI LETGKLRWGA

VK
Length:52
Mass (Da):5,848
Last modified:February 22, 2012 - v1
Checksum:i9D2FB3047CDA5CDA
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5VUJ9DRC8_HUMAN
Dynein regulatory complex protein 8
EFCAB2 DRC8
269Annotation score:
H7BY53H7BY53_HUMAN
Dynein regulatory complex protein 8
EFCAB2
221Annotation score:
H0Y6F0H0Y6F0_HUMAN
Dynein regulatory complex protein 8
EFCAB2
127Annotation score:
H0YHT5H0YHT5_HUMAN
Dynein regulatory complex protein 8
EFCAB2
131Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL356512 Genomic DNA No translation available.
AL589763 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000427529; ENSP00000397120; ENSG00000203666
UCSCiuc057qxt.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL356512 Genomic DNA No translation available.
AL589763 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y588
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH0Y588

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000427529; ENSP00000397120; ENSG00000203666
UCSCiuc057qxt.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000203666.12
HGNCiHGNC:28166 EFCAB2
OpenTargetsiENSG00000203666
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0027 Eukaryota
COG5126 LUCA
GeneTreeiENSGT00670000097718

Miscellaneous databases

ChiTaRSiEFCAB2 human

Gene expression databases

BgeeiENSG00000203666 Expressed in 209 organ(s), highest expression level in right uterine tube
ExpressionAtlasiH0Y588 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y588_HUMAN
AccessioniPrimary (citable) accession number: H0Y588
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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