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UniProtKB - H0Y3S9 (H0Y3S9_HUMAN)
Protein
Submitted name:
AT-rich interactive domain-containing protein 1B
Gene
ARID1B
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: InterPro
GO - Biological processi
- chromatin remodeling Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: AT-rich interactive domain-containing protein 1B |
Gene namesi | Name:ARID1B |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:18040, ARID1B |
VEuPathDBi | HostDB:ENSG00000049618 |
Subcellular locationi
Nucleus
- brahma complex Source: InterPro
- nBAF complex Source: InterPro
- SWI/SNF complex Source: InterPro
PTM / Processingi
Proteomic databases
MaxQBi | H0Y3S9 |
PeptideAtlasi | H0Y3S9 |
PRIDEi | H0Y3S9 |
ProteomicsDBi | 34589 |
Expressioni
Gene expression databases
Bgeei | ENSG00000049618, Expressed in female reproductive system and 232 other tissues |
ExpressionAtlasi | H0Y3S9, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 120 – 211 | ARIDInterPro annotationAdd BLAST | 92 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 54 | DisorderedSequence analysisAdd BLAST | 54 | |
Regioni | 69 – 111 | DisorderedSequence analysisAdd BLAST | 43 | |
Regioni | 215 – 273 | DisorderedSequence analysisAdd BLAST | 59 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 81 – 95 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 96 – 111 | Polar residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 258 – 273 | Polar residuesSequence analysisAdd BLAST | 16 |
Phylogenomic databases
GeneTreei | ENSGT00940000155634 |
HOGENOMi | CLU_1079877_0_0_1 |
Family and domain databases
Gene3Di | 1.10.150.60, 1 hit |
InterProi | View protein in InterPro IPR038040, ARID1B IPR001606, ARID_dom IPR036431, ARID_dom_sf IPR021906, BAF250/Osa |
PANTHERi | PTHR12656, PTHR12656, 2 hits PTHR12656:SF11, PTHR12656:SF11, 2 hits |
Pfami | View protein in Pfam PF01388, ARID, 1 hit |
SMARTi | View protein in SMART SM00501, BRIGHT, 1 hit |
SUPFAMi | SSF46774, SSF46774, 1 hit |
PROSITEi | View protein in PROSITE PS51011, ARID, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 19 potential isoforms that are computationally mapped.Show allAlign All
H0Y3S9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
AAVMQAAANS AQSRQGSFPG MNQSGLMASS SPYSQPMNNS SSLMNTQAPP
60 70 80 90 100
YSMAPAMVNS SAASVGLADM MSPGESKLPL PLKADGKEEG TPQPESKSKK
110 120 130 140 150
SSSSTTTGEK ITKVYELGNE PERKLWVDRY LTFMEERGSP VSSLPAVGKK
160 170 180 190 200
PLDLFRLYVC VKEIGGLAQV NKNKKWRELA TNLNVGTSSS AASSLKKQYI
210 220 230 240 250
QYLFAFECKI ERGEEPPPEV FSTGDTKKQP KLQPPSPGKW RRCSHWPRKA
260 270
QAPGLGGSGK VVSQSGQQGT WDF
Computationally mapped potential isoform sequencesi
There are 19 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8NFD5 | ARI1B_HUMAN | AT-rich interactive domain-containi... | ARID1B BAF250B, DAN15, KIAA1235, OSA2 | 2,319 | Annotation score: | ||
H0Y7H8 | H0Y7H8_HUMAN | AT-rich interactive domain-containi... | ARID1B | 1,758 | Annotation score: | ||
A0A1B0GVK1 | A0A1B0GVK1_HUMAN | AT-rich interactive domain-containi... | ARID1B | 1,539 | Annotation score: | ||
A0A3F2YNW7 | A0A3F2YNW7_HUMAN | AT-rich interactive domain-containi... | ARID1B | 2,332 | Annotation score: | ||
A0A1B0GTJ8 | A0A1B0GTJ8_HUMAN | AT-rich interactive domain-containi... | ARID1B | 1,495 | Annotation score: | ||
A0A1B0GWJ2 | A0A1B0GWJ2_HUMAN | AT-rich interactive domain-containi... | ARID1B | 1,479 | Annotation score: | ||
A0A1B0GV63 | A0A1B0GV63_HUMAN | AT-rich interactive domain-containi... | ARID1B | 1,349 | Annotation score: | ||
H0Y2R3 | H0Y2R3_HUMAN | AT-rich interactive domain-containi... | ARID1B | 727 | Annotation score: | ||
A0A6Q8NVI4 | A0A6Q8NVI4_HUMAN | AT-rich interactive domain-containi... | ARID1B | 2,372 | Annotation score: | ||
A0A1B0GTI6 | A0A1B0GTI6_HUMAN | AT-rich interactive domain-containi... | ARID1B | 312 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL049820 Genomic DNA No translation available. AL136091 Genomic DNA No translation available. AL162578 Genomic DNA No translation available. AL355297 Genomic DNA No translation available. AL591545 Genomic DNA No translation available. KF458328 Genomic DNA No translation available. KF458335 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000400790.3; ENSP00000383596.3; ENSG00000049618.24 |
UCSCi | uc063sml.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL049820 Genomic DNA No translation available. AL136091 Genomic DNA No translation available. AL162578 Genomic DNA No translation available. AL355297 Genomic DNA No translation available. AL591545 Genomic DNA No translation available. KF458328 Genomic DNA No translation available. KF458335 Genomic DNA No translation available. |
3D structure databases
SMRi | H0Y3S9 |
ModBasei | Search... |
Proteomic databases
MaxQBi | H0Y3S9 |
PeptideAtlasi | H0Y3S9 |
PRIDEi | H0Y3S9 |
ProteomicsDBi | 34589 |
Protocols and materials databases
Antibodypediai | 19980, 161 antibodies from 27 providers |
Genome annotation databases
Ensembli | ENST00000400790.3; ENSP00000383596.3; ENSG00000049618.24 |
UCSCi | uc063sml.1, human |
Organism-specific databases
HGNCi | HGNC:18040, ARID1B |
OpenTargetsi | ENSG00000049618 |
VEuPathDBi | HostDB:ENSG00000049618 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155634 |
HOGENOMi | CLU_1079877_0_0_1 |
Miscellaneous databases
ChiTaRSi | ARID1B, human |
Gene expression databases
Bgeei | ENSG00000049618, Expressed in female reproductive system and 232 other tissues |
ExpressionAtlasi | H0Y3S9, baseline and differential |
Family and domain databases
Gene3Di | 1.10.150.60, 1 hit |
InterProi | View protein in InterPro IPR038040, ARID1B IPR001606, ARID_dom IPR036431, ARID_dom_sf IPR021906, BAF250/Osa |
PANTHERi | PTHR12656, PTHR12656, 2 hits PTHR12656:SF11, PTHR12656:SF11, 2 hits |
Pfami | View protein in Pfam PF01388, ARID, 1 hit |
SMARTi | View protein in SMART SM00501, BRIGHT, 1 hit |
SUPFAMi | SSF46774, SSF46774, 1 hit |
PROSITEi | View protein in PROSITE PS51011, ARID, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | H0Y3S9_HUMAN | |
Accessioni | H0Y3S9Primary (citable) accession number: H0Y3S9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | May 25, 2022 | |
This is version 65 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |