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Protein
Submitted name:

Lipase member I

Gene

LIPI

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Lipase member IImported
Gene namesi
Name:LIPIImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 21

Organism-specific databases

EuPathDBiHostDB:ENSG00000188992.11
HGNCiHGNC:18821 LIPI

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000188992

PTM / Processingi

Proteomic databases

PeptideAtlasiH0Y3S0
PRIDEiH0Y3S0

Expressioni

Gene expression databases

BgeeiENSG00000188992 Expressed in 52 organ(s), highest expression level in caput epididymis
ExpressionAtlasiH0Y3S0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y3S0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 96LipaseInterPro annotationAdd BLAST95

Sequence similaritiesi

Belongs to the AB hydrolase superfamily. Lipase family.UniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000119069

Family and domain databases

Gene3Di3.40.50.1820, 2 hits
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR013818 Lipase/vitellogenin
IPR000734 TAG_lipase
PANTHERiPTHR11610 PTHR11610, 2 hits
PfamiView protein in Pfam
PF00151 Lipase, 1 hit
PRINTSiPR00821 TAGLIPASE
SUPFAMiSSF53474 SSF53474, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

H0Y3S0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XYNRAVKNTR KVAVSLSVHI KNLLKHGASL DNFHFIGVSL GAHISGFVGK
60 70 80 90 100
IFHGQLGRIT GLDPAGPRFS RKPPYSRLDY TDAKFVDVIH SDSNGIQFIK
110 120 130 140
CNHQRAVHLF MASLETNCNF ISFPCRSYKD YKTSLCVDCD C
Length:141
Mass (Da):15,774
Last modified:February 22, 2012 - v1
Checksum:iF7AE4B4A760B72E2
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6XZB0LIPI_HUMAN
Lipase member I
LIPI LPDL, PRED5
460Annotation score:
A0A087WZG8A0A087WZG8_HUMAN
Lipase member I
LIPI
421Annotation score:
A0A2Q2TCK2A0A2Q2TCK2_HUMAN
Lipase member I
LIPI
451Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei141Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF130358 Genomic DNA No translation available.
AL078615 Genomic DNA No translation available.
AP001347 Genomic DNA No translation available.
KC877767 Genomic DNA No translation available.
KC877770 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000400211; ENSP00000383072; ENSG00000188992
UCSCiuc061zbg.1 human

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF130358 Genomic DNA No translation available.
AL078615 Genomic DNA No translation available.
AP001347 Genomic DNA No translation available.
KC877767 Genomic DNA No translation available.
KC877770 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y3S0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiH0Y3S0
PRIDEiH0Y3S0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000400211; ENSP00000383072; ENSG00000188992
UCSCiuc061zbg.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000188992.11
HGNCiHGNC:18821 LIPI
OpenTargetsiENSG00000188992
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000119069

Miscellaneous databases

ChiTaRSiLIPI human

Gene expression databases

BgeeiENSG00000188992 Expressed in 52 organ(s), highest expression level in caput epididymis
ExpressionAtlasiH0Y3S0 baseline and differential

Family and domain databases

Gene3Di3.40.50.1820, 2 hits
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR013818 Lipase/vitellogenin
IPR000734 TAG_lipase
PANTHERiPTHR11610 PTHR11610, 2 hits
PfamiView protein in Pfam
PF00151 Lipase, 1 hit
PRINTSiPR00821 TAGLIPASE
SUPFAMiSSF53474 SSF53474, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y3S0_HUMAN
AccessioniPrimary (citable) accession number: H0Y3S0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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