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Protein
Submitted name:

SET domain-containing protein 5

Gene

SETD5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
SET domain-containing protein 5Imported
Gene namesi
Name:SETD5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000168137.15
HGNCiHGNC:25566 SETD5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000168137

PTM / Processingi

Proteomic databases

MaxQBiH0Y3R4
PeptideAtlasiH0Y3R4
PRIDEiH0Y3R4

Expressioni

Gene expression databases

BgeeiENSG00000168137 Expressed in 227 organ(s), highest expression level in intestine
ExpressionAtlasiH0Y3R4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliH0Y3R4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 58SETInterPro annotationAdd BLAST58

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili109 – 136Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IMXD Eukaryota
ENOG410ZTNX LUCA
GeneTreeiENSGT00520000055602

Family and domain databases

InterProiView protein in InterPro
IPR001214 SET_dom
PfamiView protein in Pfam
PF00856 SET, 1 hit
PROSITEiView protein in PROSITE
PS50280 SET, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

H0Y3R4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XVEMCVDART FGNDARFIRR SCTPNAEVRH MIADGMIHLC IYAVSAITKD
60 70 80 90 100
AEVTIAFDYE YSNCNYKVDC ACHKGNRNCP IQKRNPNATE LPLLPPPPSL
110 120 130 140 150
PTIGAETRRR KARRKELEME QQNEASEENN DQQSQEVPEK VTVSSDHEEV
160 170 180 190 200
DNPEEKPEEE KEEVIDDQEN LAHSRRTRED RKVEAIMHAF ENLEKRKKRR
210 220 230 240 250
DQPLEQSNSD VEITTTTSET PVGEETKTEA PESEVSNSVS NVTIPSTPQS
260 270 280 290 300
VGVNTRRSSQ AGDIAAEKLV PKPPPAKPSR PRPKSRISRY RTSSAQRLKR
310 320 330 340 350
QKQANAQQAE LSQAALEEGG SNSLVTPTEA GSLDSSGENR PLTGSDPTVV
360 370 380 390 400
SITGSHVNRA ASKYPKTKKY LVTEWLNDKA EKQECPVECP LRITTDPTVL
410 420 430 440 450
ATTLNMLPGL IHSPLICTTP KHYIRFGSPF IPERRRRPLL PDGTFSSCKK
460 470 480 490 500
RWIKQALEEG MTQTSSVPQE TRTQHLYQSN ENSSSSSICK DNADLLSPLK
510 520 530 540 550
KWKSRYLMEQ NVTKLLRPLS PVTPPPPNSG SKSPQLATPG SSHPGEEECR
560 570 580 590 600
NGYSLMFSPV TSLTTASRCN TPLQFELCHR KDLDLAKVGY LDSNTNSCAD
610 620 630 640 650
RPSLLNSGHS DLAPHPSLGP TSETGFPSRS GDGHQTLVRN SDQAFRTEFN
660 670 680 690 700
LMYAYSPLNA MPRADGLYRG SPLVGDRKPL HLDGGYCSPA EGFSSRYEHG
710 720 730 740 750
LMKDLSRGSL SPGGERACEG VPSAPQNPPQ RKKVSLLEYR KRKQEAKENS
760 770 780 790 800
AGGGGDSAQS KSKSAGAGQG SSNSVSDTGA HGVQGSSART PSSPHKKFSP
810 820 830 840 850
SHSSMSHLEA VSPSDSRGTS SSHCRPQENI SSRWMVPTSV ERLREGGSIP
860 870 880 890 900
KVLRSSVRVA QKGEPSPTWE SNITEKDSDP ADGEGPETLS SALSKGATVY
910
SPSRYSYQIC D
Length:911
Mass (Da):99,822
Last modified:February 22, 2012 - v1
Checksum:iB72E0BC8F67B2193
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9C0A6SETD5_HUMAN
SET domain-containing protein 5
SETD5 KIAA1757
1,442Annotation score:
E7EWN3E7EWN3_HUMAN
SET domain-containing protein 5
SETD5
1,461Annotation score:
H7C1Q2H7C1Q2_HUMAN
SET domain-containing protein 5
SETD5
177Annotation score:
C9JLA7C9JLA7_HUMAN
SET domain-containing protein 5
SETD5
162Annotation score:
C9JLM1C9JLM1_HUMAN
SET domain-containing protein 5
SETD5
170Annotation score:
H7C1F2H7C1F2_HUMAN
SET domain-containing protein 5
SETD5
441Annotation score:
F8WD12F8WD12_HUMAN
SET domain-containing protein 5
SETD5
65Annotation score:
F2Z2J0F2Z2J0_HUMAN
SET domain-containing protein 5
SETD5
52Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018506 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000399686; ENSP00000382593; ENSG00000168137
UCSCiuc062gki.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018506 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliH0Y3R4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiH0Y3R4
PeptideAtlasiH0Y3R4
PRIDEiH0Y3R4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000399686; ENSP00000382593; ENSG00000168137
UCSCiuc062gki.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000168137.15
HGNCiHGNC:25566 SETD5
OpenTargetsiENSG00000168137
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IMXD Eukaryota
ENOG410ZTNX LUCA
GeneTreeiENSGT00520000055602

Miscellaneous databases

ChiTaRSiSETD5 human

Gene expression databases

BgeeiENSG00000168137 Expressed in 227 organ(s), highest expression level in intestine
ExpressionAtlasiH0Y3R4 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001214 SET_dom
PfamiView protein in Pfam
PF00856 SET, 1 hit
PROSITEiView protein in PROSITE
PS50280 SET, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0Y3R4_HUMAN
AccessioniPrimary (citable) accession number: H0Y3R4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 12, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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