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UniProtKB - H0Y3E8 (H0Y3E8_HUMAN)
Protein
Submitted name:
Dystrophin
Gene
DMD
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- zinc ion binding Source: InterPro
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Dystrophin |
Gene namesi | Name:DMD |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:2928, DMD |
VEuPathDBi | HostDB:ENSG00000198947 |
Expressioni
Gene expression databases
Bgeei | ENSG00000198947, Expressed in trigeminal ganglion and 248 other tissues |
ExpressionAtlasi | H0Y3E8, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 97 – 144 | ZZ-typeInterPro annotationAdd BLAST | 48 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000154342 |
HOGENOMi | CLU_081409_1_0_1 |
Family and domain databases
Gene3Di | 3.30.60.90, 1 hit |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR015154, EF-hand_dom_typ2 IPR000433, Znf_ZZ IPR043145, Znf_ZZ_sf |
Pfami | View protein in Pfam PF09069, EF-hand_3, 1 hit PF00569, ZZ, 1 hit |
SMARTi | View protein in SMART SM00291, ZnF_ZZ, 1 hit |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS01357, ZF_ZZ_1, 1 hit PS50135, ZF_ZZ_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 36 potential isoforms that are computationally mapped.Show allAlign All
H0Y3E8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
LEDKYRYLFK QVASSTGFCD QRRLGLLLHD SIQIPRQLGE VASFGGSNIE
60 70 80 90 100
PSVRSCFQFA NNKPEIEAAL FLDWMRLEPQ SMVWLPVLHR VAAAETAKHQ
110 120 130 140 150
AKCNICKECP IIGFRYRSLK HFNYDICQSC FFSGRVAKGH KMHYPMVEYC
160 170 180 190 200
TPTTSGEDVR DFAKVLKNKF RTKRYFAKHP RMGYLPVQTV LEGDNMETPV
210 220 230
TLINFWPVDS APASSPQLSH DDTHSRIEHY ASRDDEHL
Computationally mapped potential isoform sequencesi
There are 36 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP11532 | DMD_HUMAN | Dystrophin | DMD | 3,685 | Annotation score: | ||
A0A075B6G3 | A0A075B6G3_HUMAN | Dystrophin | DMD | 3,685 | Annotation score: | ||
A0A5H1ZRP8 | A0A5H1ZRP8_HUMAN | Dystrophin | DMD | 3,681 | Annotation score: | ||
A0A087WV90 | A0A087WV90_HUMAN | Dystrophin | DMD | 2,341 | Annotation score: | ||
A0A087WTU7 | A0A087WTU7_HUMAN | Dystrophin | DMD | 1,154 | Annotation score: | ||
A0A5H1ZRQ1 | A0A5H1ZRQ1_HUMAN | Dystrophin | DMD | 1,225 | Annotation score: | ||
A0A5H1ZRP7 | A0A5H1ZRP7_HUMAN | Dystrophin | DMD | 970 | Annotation score: | ||
A0A5H1ZRR9 | A0A5H1ZRR9_HUMAN | Dystrophin | DMD | 1,115 | Annotation score: | ||
H0Y304 | H0Y304_HUMAN | Dystrophin | DMD | 1,386 | Annotation score: | ||
A0A5H1ZRP9 | A0A5H1ZRP9_HUMAN | Dystrophin | DMD | 1,230 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | 1 | ||
Non-terminal residuei | 238 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC006061 Genomic DNA No translation available. AC078957 Genomic DNA No translation available. AC078958 Genomic DNA No translation available. AC079143 Genomic DNA No translation available. AC079175 Genomic DNA No translation available. AC079177 Genomic DNA No translation available. AC079864 Genomic DNA No translation available. AC090632 Genomic DNA No translation available. AC093167 Genomic DNA No translation available. AC093193 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000378705.3; ENSP00000367977.3; ENSG00000198947.18 |
UCSCi | uc064ylx.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC006061 Genomic DNA No translation available. AC078957 Genomic DNA No translation available. AC078958 Genomic DNA No translation available. AC079143 Genomic DNA No translation available. AC079175 Genomic DNA No translation available. AC079177 Genomic DNA No translation available. AC079864 Genomic DNA No translation available. AC090632 Genomic DNA No translation available. AC093167 Genomic DNA No translation available. AC093193 Genomic DNA No translation available. |
3D structure databases
SMRi | H0Y3E8 |
ModBasei | Search... |
Proteomic databases
MaxQBi | H0Y3E8 |
PeptideAtlasi | H0Y3E8 |
ProteomicsDBi | 34496 |
Protocols and materials databases
Antibodypediai | 476, 632 antibodies from 38 providers |
Genome annotation databases
Ensembli | ENST00000378705.3; ENSP00000367977.3; ENSG00000198947.18 |
UCSCi | uc064ylx.1, human |
Organism-specific databases
HGNCi | HGNC:2928, DMD |
OpenTargetsi | ENSG00000198947 |
VEuPathDBi | HostDB:ENSG00000198947 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154342 |
HOGENOMi | CLU_081409_1_0_1 |
Miscellaneous databases
ChiTaRSi | DMD, human |
Gene expression databases
Bgeei | ENSG00000198947, Expressed in trigeminal ganglion and 248 other tissues |
ExpressionAtlasi | H0Y3E8, baseline and differential |
Family and domain databases
Gene3Di | 3.30.60.90, 1 hit |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR015154, EF-hand_dom_typ2 IPR000433, Znf_ZZ IPR043145, Znf_ZZ_sf |
Pfami | View protein in Pfam PF09069, EF-hand_3, 1 hit PF00569, ZZ, 1 hit |
SMARTi | View protein in SMART SM00291, ZnF_ZZ, 1 hit |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS01357, ZF_ZZ_1, 1 hit PS50135, ZF_ZZ_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | H0Y3E8_HUMAN | |
Accessioni | H0Y3E8Primary (citable) accession number: H0Y3E8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 22, 2012 |
Last sequence update: | February 22, 2012 | |
Last modified: | May 25, 2022 | |
This is version 64 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |