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Entry version 61 (29 Sep 2021)
Sequence version 1 (22 Feb 2012)
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Protein
Submitted name:

Nesprin-1

Gene

SYNE1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nesprin-1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SYNE1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:17089, SYNE1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000131018

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000131018

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
H0Y325

PeptideAtlas

More...
PeptideAtlasi
H0Y325

PRoteomics IDEntifications database

More...
PRIDEi
H0Y325

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
34421

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000131018, Expressed in cerebellum and 239 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
H0Y325, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
H0Y325

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1168 – 1203DisorderedSequence analysisAdd BLAST36
Regioni1618 – 1642DisorderedSequence analysisAdd BLAST25

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili85 – 115Sequence analysisAdd BLAST31
Coiled coili569 – 589Sequence analysisAdd BLAST21
Coiled coili734 – 761Sequence analysisAdd BLAST28
Coiled coili841 – 861Sequence analysisAdd BLAST21
Coiled coili1413 – 1433Sequence analysisAdd BLAST21
Coiled coili1587 – 1611Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1169 – 1189Polar residuesSequence analysisAdd BLAST21
Compositional biasi1618 – 1639Polar residuesSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154481

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00435, Spectrin, 8 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00150, SPEC, 11 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 24 potential isoforms that are computationally mapped.Show allAlign All

H0Y325-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
EKIEQNGLAL IQNKKEDVSS IVMSTLRELG QTWANLDHMV GQLKILLKSV
60 70 80 90 100
LDQWSSHKVA FDKINSYLME ARYSLSRFRL LTGSLEAVQV QVDNLQNLQD
110 120 130 140 150
DLEKQERSLQ KFGSITNQLL KECHPPVTET LTNTLKEVNM RWNNLLEEIA
160 170 180 190 200
EQLQSSKALL QLWQRYKDYS KQCASTVQQQ EDRTNELLKA ATNKDIADDE
210 220 230 240 250
VATWIQDCND LLKGLGTVKD SLFFLHELGE QLKQQVDASA ASAIQSDQLS
260 270 280 290 300
LSQHLCALEQ ALCKQQTSLQ AGVLDYETFA KSLEALEAWI VEAEEILQGQ
310 320 330 340 350
DPSHSSDLST IQERMEELKG QMLKFSSMAP DLDRLNELGY RLPLNDKEIK
360 370 380 390 400
RMQNLNRHWS LISSQTTERF SKLQSFLLQH QTFLEKCETW MEFLVQTEQK
410 420 430 440 450
LAVEISGNYQ HLLEQQRAHE LFQAEMFSRQ QILHSIIIDG QRLLEQGQVD
460 470 480 490 500
DRDEFNLKLT LLSNQWQGVI RRAQQRRGII DSQIRQWQRY REMAEKLRKW
510 520 530 540 550
LVEVSYLPMS GLGSVPIPLQ QARTLFDEVQ FKEKVFLRQQ GSYILTVEAG
560 570 580 590 600
KQLLLSADSG AEAALQAELA EIQEKWKSAS MRLEEQKKKL AFLLKDWEKC
610 620 630 640 650
EKGIADSLEK LRTFKKKLSQ SLPDHHEELH AEQMRCKELE NAVGSWTDDL
660 670 680 690 700
TQLSLLKDTL SAYISADDIS ILNERVELLQ RQWEELCHQL SLRRQQIGER
710 720 730 740 750
LNEWAVFSEK NKELCEWLTQ MESKVSQNGD ILIEEMIEKL KKDYQEEIAI
760 770 780 790 800
AQENKIQLQQ MGERLAKASH ESKASEIEYK LGKVNDRWQH LLDLIAARVK
810 820 830 840 850
KLKETLVAVQ QLDKNMSSLR TWLAHIESEL AKPIVYDSCN SEEIQRKLNE
860 870 880 890 900
QQELQRDIEK HSTGVASVLN LCEVLLHDCD ACATDAECDS IQQATRNLDR
910 920 930 940 950
RWRNICAMSM ERRLKIEETW RLWQKFLDDY SRFEDWLKSS ERTAAFPSSS
960 970 980 990 1000
GVIYTVAKEE LKKFEAFQRQ VHECLTQLEL INKQYRRLAR ENRTDSACSL
1010 1020 1030 1040 1050
KQMVHEGNQR WDNLQKRVTS ILRRLKHFIG QREEFETARD SILVWLTEMD
1060 1070 1080 1090 1100
LQLTNIEHFS ECDVQAKIKQ LKAFQQEISL NHNKIEQIIA QGEQLIEKSE
1110 1120 1130 1140 1150
PLDAAIIEEE LDELRRYCQE VFGRVERYHK KLIRLPLPDD EHDLSDRELE
1160 1170 1180 1190 1200
LEDSAALSDL HWHDRSADSL LSPQPSSNLS LSLAQPLRSE RSGRDTPASV
1210 1220 1230 1240 1250
DSIPLEWDHD YDLSRDLESA MSRALPSEDE EGQDDKDFYL RGAVGLSDVM
1260 1270 1280 1290 1300
IPESPEAYVK LTENAIKNTS GDHSALESQI RQLGKALDDS RFQIQQTENI
1310 1320 1330 1340 1350
IRSKTPTGPE LDTSYKGYMK LLGECSSSID SVKRLEHKLK EEEESLPGFV
1360 1370 1380 1390 1400
NLHSTETQTA GVIDRWELLQ AQALSKELRM KQNLQKWQQF NSDLNSIWAW
1410 1420 1430 1440 1450
LGDTEEELEQ LQRLELSTDI QTIELQIKKL KELQKAVDHR KAIILSINLC
1460 1470 1480 1490 1500
SPEFTQADSK ESRDLQDRLS QMNGRWDRVC SLLEEWRGLL QDALMQCQGF
1510 1520 1530 1540 1550
HEMSHGLLLM LENIDRRKNE IVPIDSNLDA EILQDHHKQL MQIKHELLES
1560 1570 1580 1590 1600
QLRVASLQDM SCQLLVNAEG TDCLEAKEKV HVIGNRLKLL LKEVSRHIKE
1610 1620 1630 1640 1650
LEKLLDVSSS QQDLSSWSSA DELDTSGSVS PTSGRSTPNR QKTVHKRWLR

FLPF
Length:1,654
Mass (Da):191,475
Last modified:February 22, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0E4ED7857FF7518D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 24 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8NF91SYNE1_HUMAN
Nesprin-1
SYNE1 C6orf98, KIAA0796, KIAA1262, KIAA1756, MYNE1
8,797Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0C4DG40A0A0C4DG40_HUMAN
Nesprin-1
SYNE1
8,749Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WAI0F8WAI0_HUMAN
Nesprin-1
SYNE1
975Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5JV20Q5JV20_HUMAN
Nesprin-1
SYNE1
952Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y326H0Y326_HUMAN
Nesprin-1
SYNE1
1,355Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5GZ83F5GZ83_HUMAN
Nesprin-1
SYNE1
195Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F9ZH87A0A5F9ZH87_HUMAN
Nesprin-1
SYNE1
542Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F9ZH86A0A5F9ZH86_HUMAN
Nesprin-1
SYNE1
510Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F9ZHB2A0A5F9ZHB2_HUMAN
Nesprin-1
SYNE1
591Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F9ZHE1A0A5F9ZHE1_HUMAN
Nesprin-1
SYNE1
635Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL049548 Genomic DNA No translation available.
AL078582 Genomic DNA No translation available.
AL136079 Genomic DNA No translation available.
AL138832 Genomic DNA No translation available.
AL357081 Genomic DNA No translation available.
AL450401 Genomic DNA No translation available.
AL589963 Genomic DNA No translation available.
AL591507 Genomic DNA No translation available.
KF458330 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000367251; ENSP00000356220; ENSG00000131018

UCSC genome browser

More...
UCSCi
uc063shu.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL049548 Genomic DNA No translation available.
AL078582 Genomic DNA No translation available.
AL136079 Genomic DNA No translation available.
AL138832 Genomic DNA No translation available.
AL357081 Genomic DNA No translation available.
AL450401 Genomic DNA No translation available.
AL589963 Genomic DNA No translation available.
AL591507 Genomic DNA No translation available.
KF458330 Genomic DNA No translation available.

3D structure databases

SMRiH0Y325
ModBaseiSearch...

Proteomic databases

MaxQBiH0Y325
PeptideAtlasiH0Y325
PRIDEiH0Y325
ProteomicsDBi34421

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
19931, 157 antibodies

Genome annotation databases

EnsembliENST00000367251; ENSP00000356220; ENSG00000131018
UCSCiuc063shu.1, human

Organism-specific databases

HGNCiHGNC:17089, SYNE1
OpenTargetsiENSG00000131018
VEuPathDBiHostDB:ENSG00000131018

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000154481

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
SYNE1, human

Gene expression databases

BgeeiENSG00000131018, Expressed in cerebellum and 239 other tissues
ExpressionAtlasiH0Y325, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat
PfamiView protein in Pfam
PF00435, Spectrin, 8 hits
SMARTiView protein in SMART
SM00150, SPEC, 11 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH0Y325_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H0Y325
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 29, 2021
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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