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Entry version 41 (11 Dec 2019)
Sequence version 1 (22 Feb 2012)
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Protein
Submitted name:

AT-rich interaction domain 2

Gene

ARID2

Organism
Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AT-rich interaction domain 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARID2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOtolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri30611 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesStrepsirrhiniLorisiformesGalagidaeOtolemur
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005225 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini433 – 512RFX-type winged-helixInterPro annotationAdd BLAST80

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni722 – 753DisorderedSequence analysisAdd BLAST32
Regioni801 – 828DisorderedSequence analysisAdd BLAST28
Regioni871 – 960DisorderedSequence analysisAdd BLAST90
Regioni1171 – 1191DisorderedSequence analysisAdd BLAST21
Regioni1226 – 1245DisorderedSequence analysisAdd BLAST20
Regioni1478 – 1531DisorderedSequence analysisAdd BLAST54
Regioni1608 – 1635DisorderedSequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi887 – 960PolarSequence analysisAdd BLAST74
Compositional biasi1174 – 1191PolarSequence analysisAdd BLAST18
Compositional biasi1478 – 1499PolarSequence analysisAdd BLAST22
Compositional biasi1507 – 1530PolarSequence analysisAdd BLAST24
Compositional biasi1609 – 1635PolarSequence analysisAdd BLAST27

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2312 Eukaryota
ENOG410XT3H LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000016138

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR003150 DNA-bd_RFX
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02257 RFX_DNA_binding, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46785 SSF46785, 1 hit
SSF48371 SSF48371, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51526 RFX_DBD, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

H0XPL3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
FYFSYLEKYE KVHHFGEDDD EVPPGNPKPQ LPIGAIPSSY NYQQHSVSDY
60 70 80 90 100
LRQSYGLSMD FNSPNDYNKL VLSLLSGLPN EVDFAINVCT LLSNESKHVM
110 120 130 140 150
QLEKDPKIIT LLLANAGVFD DTLGSFSTVF GEEWKEKTDR DFVKFWKDIV
160 170 180 190 200
DDNEVRDLIS DRNKSHEGTS GEWIWESLFH PPRKLGINDI EGQRVLQIAV
210 220 230 240 250
ILRNLSFEEG NVKLLAANRT CLRFLLLSAH SHFISLRQLG LDTLGNIAAE
260 270 280 290 300
LLLDPVDFKT THLMFHTVTK CLMSRDRFLK MRGMEILGNL CKAEDNGVLI
310 320 330 340 350
CEYVDQDSYR EIICHLTLPD VLLVISTLEV LYMLTEMGDV ACTKIAKVEK
360 370 380 390 400
SIDMLVCLVS MDIQMFGPDA LAAVKLVEHP SSSHQVLSEI RPQAVEQVQT
410 420 430 440 450
QTHVASAPAS RAVVAQHVAP PPGIVEIDSE KFACQWLNAH FEVNPDCSVS
460 470 480 490 500
RAEMYSEYLS TCSKLARGGI LTSTGFYKCL RTVFPNHTVK RVEDSSNNGQ
510 520 530 540 550
AHIHVVGVKR RAIPLPIQMY YQQQPVSTPV VRVDSVPDVS PTPSPAGIPH
560 570 580 590 600
GSQTVGNHFQ RTSVTNQSSN LTATQMSFPV QGVHTVAQTV SRIPPNPSVH
610 620 630 640 650
THQQQNAPVT VIQNKAPISC EVVKATVIQN SMPQTAVPVS IAVGGGPPQS
660 670 680 690 700
SVVQNHSTGP QPVTVVNSQT LLHHPSVIPQ QSSLHTVVPG QIPSGTPVTV
710 720 730 740 750
IQQAVPQSHI FGRVQNIPPC TSTVSQGQPL ITTSPQPVQT SSQQTSAGSQ
760 770 780 790 800
PQDTVIIAPP QYVTTSASNI VSATSVQNFQ VAAGQMVTIA GVPSPQPSRV
810 820 830 840 850
GFQNIAPKPL PSQQVSSTVV QQPIQQPQQP TQQSVVIVSQ PAQQGQTYAP
860 870 880 890 900
AIHQIVLANP AALPAGQTVQ LTGQPNITPS SSPSPVPTNQ VPTAMSSSST
910 920 930 940 950
PQSQGPPPTV SQMLSVKRQQ QQQHSPAPPP QQVQVQQSQQ VQMQVQPQQT
960 970 980 990 1000
NAGVGQSASG ESSLIKQLLL PKRGPSTPGG KLILPAPQIP PPNNARAPSP
1010 1020 1030 1040 1050
QVVYQVANNQ AAGFGVQGQT PAQPLLVGQQ NVQLVQSAMP PTGGVQTMPI
1060 1070 1080 1090 1100
SNLQILPGPL ISNSPATIFQ GTSGNQVTIT VVPNTSFATA TVSQGNTAQL
1110 1120 1130 1140 1150
LAPAGITMSG TQTGVGLQVQ ALPATQVSPA GQSCTTATPP FKGDKIICQK
1160 1170 1180 1190 1200
EEEAKEATGL HVHERKIEVM ENPSCRRGTT NTSNGDTKEN EMQVGNLLNG
1210 1220 1230 1240 1250
RKYSDSSLPP SNSGKIQSEA NQCSLISNGP SLELGENGAS GKQNSEQMDL
1260 1270 1280 1290 1300
QDIKSDLKKP LVNGICDFDK GDGSHLSKNI PNHKTSNHVG NGEISPMEPQ
1310 1320 1330 1340 1350
GTLDVTQQDT AKGDQLERIS NGPVLTLGGS SSVSSIQEVS NMATQQFSGT
1360 1370 1380 1390 1400
DLPNGPLASS LNSDVPQQRP SVVVSPHSTT SVIQGHQIIA VPHSGSRVSH
1410 1420 1430 1440 1450
SPALSSDVRS TNGTAECKTV KRPAEDNDRE IVTGIPNKVG VRIVTISDPN
1460 1470 1480 1490 1500
NAGCSATMVA VPAGADPSTV AKVAIESAVQ QKQQHPPTYI QNVVPQNTPM
1510 1520 1530 1540 1550
SPSPAVPVQG QPNSSQPSSF SASSQHGDPL RKPGQNFMCL WQSCKKWFQT
1560 1570 1580 1590 1600
PSQVFYHAAT EHGGKDVYPG QCLWEGCEPF QRQRFSFITH LQDKHCSKDA
1610 1620 1630 1640 1650
LLAGLKQDEQ GQAGSQKSST KQPTVGGTGS TPRAQKAIVN HPSAALMALR
1660 1670 1680 1690 1700
RGSRNLVFRD FTDEKEGPIT KHIRLTAALI LKNIGKYSEC GRRLLKRHEN
1710 1720 1730
NLSVLAISNM EASSTLAKCL YELNFTIQSK EQDSEMLQ
Length:1,738
Mass (Da):186,843
Last modified:February 22, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD8DCF9C04AECF727
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0XVP2H0XVP2_OTOGA
AT-rich interaction domain 2
ARID2
1,770Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAQR03104056 Genomic DNA No translation available.
AAQR03104057 Genomic DNA No translation available.
AAQR03104058 Genomic DNA No translation available.
AAQR03104059 Genomic DNA No translation available.
AAQR03104060 Genomic DNA No translation available.
AAQR03104061 Genomic DNA No translation available.
AAQR03104062 Genomic DNA No translation available.
AAQR03104063 Genomic DNA No translation available.
AAQR03104064 Genomic DNA No translation available.
AAQR03104065 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSOGAT00000024152; ENSOGAP00000018054; ENSOGAG00000024418

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAQR03104056 Genomic DNA No translation available.
AAQR03104057 Genomic DNA No translation available.
AAQR03104058 Genomic DNA No translation available.
AAQR03104059 Genomic DNA No translation available.
AAQR03104060 Genomic DNA No translation available.
AAQR03104061 Genomic DNA No translation available.
AAQR03104062 Genomic DNA No translation available.
AAQR03104063 Genomic DNA No translation available.
AAQR03104064 Genomic DNA No translation available.
AAQR03104065 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSOGAT00000024152; ENSOGAP00000018054; ENSOGAG00000024418

Phylogenomic databases

eggNOGiKOG2312 Eukaryota
ENOG410XT3H LUCA
GeneTreeiENSGT00390000016138

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR003150 DNA-bd_RFX
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF02257 RFX_DNA_binding, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51526 RFX_DBD, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH0XPL3_OTOGA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H0XPL3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: December 11, 2019
This is version 41 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
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