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Protein

Fibroblast growth factor

Gene

FGF4

Organism
Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGrowth factorSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Fibroblast growth factorUniRule annotation
Short name:
FGFUniRule annotation
Gene namesi
Name:FGF4Imported
OrganismiOtolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)Imported
Taxonomic identifieri30611 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesStrepsirrhiniLorisiformesGalagidaeOtolemur
Proteomesi
  • UP000005225 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30UniRule annotationAdd BLAST30
ChainiPRO_500513348631 – 206Fibroblast growth factorUniRule annotationAdd BLAST176

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi30611.ENSOGAP00000010297

Family & Domainsi

Sequence similaritiesi

Belongs to the heparin-binding growth factors family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiKOG3885 Eukaryota
ENOG4111IPH LUCA
GeneTreeiENSGT00760000118859
InParanoidiH0X4Y2
OMAiYNAYESH
OrthoDBiEOG091G0NAY
TreeFamiTF317805

Family and domain databases

CDDicd00058 FGF, 1 hit
InterProiView protein in InterPro
IPR028239 FGF4
IPR002209 Fibroblast_GF_fam
IPR008996 IL1/FGF
PANTHERiPTHR11486 PTHR11486, 1 hit
PTHR11486:SF31 PTHR11486:SF31, 1 hit
PfamiView protein in Pfam
PF00167 FGF, 1 hit
PRINTSiPR00263 HBGFFGF
SMARTiView protein in SMART
SM00442 FGF, 1 hit
SUPFAMiSSF50353 SSF50353, 1 hit
PROSITEiView protein in PROSITE
PS00247 HBGF_FGF, 1 hit

Sequencei

Sequence statusi: Complete.

H0X4Y2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGPGTAAVA LLPAVLLALL APWAGRGGAA APTAPNGTLE AELERRWESL
60 70 80 90 100
VARSLARLPV AAQPKEAAVQ SGAGDYLLGI KRLRRLYCNV GIGFHLQVLS
110 120 130 140 150
DGRIGGVHAD TSDSLLELSP VERGVVSICG VASRFFVAMS NRGKLYGSPF
160 170 180 190 200
FTDECKFKEI LLPNNYNAYE SHKYPGMFIA LSKNGKTKKG NRVSPTMKVT

HFLPRL
Length:206
Mass (Da):22,080
Last modified:February 22, 2012 - v1
Checksum:i13B29BEB27EC6646
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAQR03144576 Genomic DNA No translation available.
RefSeqiXP_003798338.1, XM_003798290.1

Genome annotation databases

EnsembliENSOGAT00000011503; ENSOGAP00000010297; ENSOGAG00000011500
GeneIDi100958629

Similar proteinsi

Entry informationi

Entry nameiH0X4Y2_OTOGA
AccessioniPrimary (citable) accession number: H0X4Y2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: March 28, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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