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Protein
Submitted name:

BRCA1 interacting protein C-terminal helicase 1

Gene

BRIP1

Organism
Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseSAAS annotation, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
BRCA1 interacting protein C-terminal helicase 1Imported
Gene namesi
Name:BRIP1Imported
OrganismiOtolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)Imported
Taxonomic identifieri30611 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesStrepsirrhiniLorisiformesGalagidaeOtolemur
Proteomesi
  • UP000005225 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi30611.ENSOGAP00000006690

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 441Helicase ATP-bindingInterPro annotationAdd BLAST431

Phylogenomic databases

eggNOGiKOG1132 Eukaryota
COG1199 LUCA
GeneTreeiENSGT00530000063199
InParanoidiH0WWD9
OMAiTNNDMNQ
OrthoDBiEOG091G00LK
TreeFamiTF329449

Family and domain databases

InterProiView protein in InterPro
IPR006555 ATP-dep_Helicase_C
IPR010614 DEAD_2
IPR014013 Helic_SF1/SF2_ATP-bd_DinG/Rad3
IPR006554 Helicase-like_DEXD_c2
IPR014001 Helicase_ATP-bd
IPR027417 P-loop_NTPase
IPR013020 Rad3/Chl1-like
PfamiView protein in Pfam
PF06733 DEAD_2, 1 hit
PF13307 Helicase_C_2, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00488 DEXDc2, 1 hit
SM00491 HELICc2, 1 hit
SUPFAMiSSF52540 SSF52540, 7 hits
TIGRFAMsiTIGR00604 rad3, 1 hit
PROSITEiView protein in PROSITE
PS51193 HELICASE_ATP_BIND_2, 1 hit

Sequencei

Sequence statusi: Complete.

H0WWD9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSMWSEYTI GGVKINFPYK AYPSQLAMMN SIVRGLNSKQ HCLLESPTGS
60 70 80 90 100
GKSLALLCSA LAWQQSLSGK PEDEGLCKKA EVPSSCCCTC HSRNFANDDM
110 120 130 140 150
NQETSHHFNN SSTPPSEGNG TLSACQDSPE KTTLAAKLSA KKQASMYRDE
160 170 180 190 200
NDDFQIEKKR IRRLETTQQI RKRHCFEKEG HHLDTKVASG KTMDPKSPLG
210 220 230 240 250
KINSFSPQNP PGHCSKCCST KQGNSQESSN TTKKDHGGKF KIPKIYFGTR
260 270 280 290 300
THKQIAQITK ELRRTAYSGV PMTILSSRDH TCVHPEVVGN FNRNEKCMEL
310 320 330 340 350
LDGKNGKSCY FYHGVHKISD QHTLQTLQGM SKAWDIEELV SLGKKLKACP
360 370 380 390 400
YYTARELIGD ADIIFCPYNY LLDSQIRESM DLNLKEQVVI LDEAHNIEDC
410 420 430 440 450
ARESASYSVT EVQLRFARDE LDSLVNNNIR KKDHEPLRAV CCSLINWLEA
460 470 480 490 500
NSEHLIERDY ESSCKIWSGS EMLLNLHRMG ITTATFPILQ GHFSAVLQKE
510 520 530 540 550
EKVSAIYGKE EAREVPIISA STQIMLKGLF MVLDYLFRQN SRFADDYKIA
560 570 580 590 600
IQQTYSWINE TNTSDKNMLV ALLPKNKKRS RQKTAVHVLN FWCLNPAVAF
610 620 630 640 650
SDINGKVRTI VLTSGTLSPM KSFSSELGVT FTIQLEANHV IKNSQVWVGT
660 670 680 690 700
IGSGPKGRNL CATFQHTETF EFQDEVGALL LSVCQTVSQG ILCFLPSYKL
710 720 730 740 750
LEKLKERWLS TGLWHNLELV KTVIVEPQGG EKTNFDELLQ LYYDAIKFKG
760 770 780 790 800
EKDGALLVAV CRGKVSEGLD FSDDNARAVI TIGIPFPNVK DLQVELKRKY
810 820 830 840 850
NDHHSKLRGV LSGRQWYEIQ AYRALNQALG RCIRHRNDWG ALILVDDRFR
860 870 880 890 900
SNPNRYISGL SKWIRQQIQH HSTFESALES LAEFSKKHQK VTNVSKKQGK
910 920 930 940 950
YIQNNESTLE VTCLKDNTPT YLLEAASHLS PENTREEEAK MCVQEPQSPE
960 970 980 990 1000
MITKNPYLPS DIISRKEKSE PTFLEETTQA MNTEKIVISR STSPTFSKQT
1010
NRVNWCSFKI L
Length:1,011
Mass (Da):114,344
Last modified:February 22, 2012 - v1
Checksum:i83DC306A1709E54B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAQR03121644 Genomic DNA No translation available.
AAQR03121645 Genomic DNA No translation available.
AAQR03121646 Genomic DNA No translation available.
AAQR03121647 Genomic DNA No translation available.
AAQR03121648 Genomic DNA No translation available.
AAQR03121649 Genomic DNA No translation available.
AAQR03121650 Genomic DNA No translation available.
AAQR03121651 Genomic DNA No translation available.
AAQR03121652 Genomic DNA No translation available.
AAQR03121653 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSOGAT00000007484; ENSOGAP00000006690; ENSOGAG00000007479

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAQR03121644 Genomic DNA No translation available.
AAQR03121645 Genomic DNA No translation available.
AAQR03121646 Genomic DNA No translation available.
AAQR03121647 Genomic DNA No translation available.
AAQR03121648 Genomic DNA No translation available.
AAQR03121649 Genomic DNA No translation available.
AAQR03121650 Genomic DNA No translation available.
AAQR03121651 Genomic DNA No translation available.
AAQR03121652 Genomic DNA No translation available.
AAQR03121653 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi30611.ENSOGAP00000006690

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOGAT00000007484; ENSOGAP00000006690; ENSOGAG00000007479

Phylogenomic databases

eggNOGiKOG1132 Eukaryota
COG1199 LUCA
GeneTreeiENSGT00530000063199
InParanoidiH0WWD9
OMAiTNNDMNQ
OrthoDBiEOG091G00LK
TreeFamiTF329449

Family and domain databases

InterProiView protein in InterPro
IPR006555 ATP-dep_Helicase_C
IPR010614 DEAD_2
IPR014013 Helic_SF1/SF2_ATP-bd_DinG/Rad3
IPR006554 Helicase-like_DEXD_c2
IPR014001 Helicase_ATP-bd
IPR027417 P-loop_NTPase
IPR013020 Rad3/Chl1-like
PfamiView protein in Pfam
PF06733 DEAD_2, 1 hit
PF13307 Helicase_C_2, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00488 DEXDc2, 1 hit
SM00491 HELICc2, 1 hit
SUPFAMiSSF52540 SSF52540, 7 hits
TIGRFAMsiTIGR00604 rad3, 1 hit
PROSITEiView protein in PROSITE
PS51193 HELICASE_ATP_BIND_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiH0WWD9_OTOGA
AccessioniPrimary (citable) accession number: H0WWD9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: March 28, 2018
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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