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Protein
Submitted name:

Nuclear receptor subfamily 4 group A member 1

Gene

NR4A1

Organism
Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi264 – 339Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 4 group A member 1Imported
Gene namesi
Name:NR4A1Imported
OrganismiOtolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)Imported
Taxonomic identifieri30611 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesStrepsirrhiniLorisiformesGalagidaeOtolemur
Proteomesi
  • UP000005225 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi30611.ENSOGAP00000005651

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini264 – 339Nuclear receptorInterPro annotationAdd BLAST76
Domaini360 – 595NR LBDInterPro annotationAdd BLAST236

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4217 Eukaryota
ENOG410YWNC LUCA
GeneTreeiENSGT00760000118887
InParanoidiH0WTY9
OMAiTDRHGLQ
OrthoDBiEOG091G0GUM
TreeFamiTF315430

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR003071 Nuc_orp_HMR_rcpt
IPR003070 Nuc_orph_rcpt
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01285 HMRNUCRECPTR
PR01284 NUCLEARECPTR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

H0WTY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPCIQAQYGT PAPSPGPRDH LASDPLTPEF SKPTMDLASP EAAPTAPTAL
60 70 80 90 100
PSFSTFMDGY TGEFDTFLYQ LPGTAQPCSS ASSSASSTSS SSATSPASAS
110 120 130 140 150
FKFEDFQVYG CYPGPLSGPL DETLSSSGSD YYGSPCSAPS PSTPSFQPPQ
160 170 180 190 200
LSPWDGSYGH FSPSQTYEGL RAWTEQLPKA SGPPQPPAFF SFSPPAGPSP
210 220 230 240 250
SLAQSSLKLF PSQAAHQLVE GDSYSMPTAF PGLAPTSPHL DGSGILDAPM
260 270 280 290 300
TSAKARSGAP GGSEGRCAVC GDSASCQHYG VRTCEGCKGF FKRTVQKNAK
310 320 330 340 350
YICLANKDCP VDKRRRNRCQ FCRFQKCLAV GMVKEVVRTD SLKGRRGRLP
360 370 380 390 400
SKPKQPPDAS PANLLTSLVR AHLDSGPSTA KLDYSKFQEL VLPRFGKEDA
410 420 430 440 450
GDVQQFYDLL SGSLEVIRKW AEKIPGFAEL SPSDQELLLE SAFLELFILR
460 470 480 490 500
LAYRSKPGEG KLIFCSGLVL HRLQCARGFG DWIDSILAFS RSLHSLAVDV
510 520 530 540 550
PAFSCLSALV LITDRHGLQE PRRVEELQNR IASCLKEHVS AMAGEPQPAG
560 570 580 590
CLSRLLGKLP ELRTLCTQGL QRIFYLKLED LVPPPPIIDK IFMDTLPF
Length:598
Mass (Da):64,429
Last modified:February 22, 2012 - v1
Checksum:iF64246E4936E408F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAQR03076488 Genomic DNA No translation available.
AAQR03076489 Genomic DNA No translation available.
RefSeqiXP_003790446.1, XM_003790398.2

Genome annotation databases

EnsembliENSOGAT00000006327; ENSOGAP00000005651; ENSOGAG00000006323
GeneIDi100956281

Similar proteinsi

Entry informationi

Entry nameiH0WTY9_OTOGA
AccessioniPrimary (citable) accession number: H0WTY9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: May 23, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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