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Protein
Submitted name:

Uncharacterized protein

Gene

ADCY9

Organism
Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
LigandNucleotide-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:ADCY9Imported
OrganismiOtolemur garnettii (Small-eared galago) (Garnett's greater bushbaby)Imported
Taxonomic identifieri30611 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesStrepsirrhiniLorisiformesGalagidaeOtolemur
Proteomesi
  • UP000005225 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei115 – 135HelicalSequence analysisAdd BLAST21
Transmembranei141 – 163HelicalSequence analysisAdd BLAST23
Transmembranei175 – 197HelicalSequence analysisAdd BLAST23
Transmembranei241 – 260HelicalSequence analysisAdd BLAST20
Transmembranei787 – 808HelicalSequence analysisAdd BLAST22
Transmembranei820 – 844HelicalSequence analysisAdd BLAST25
Transmembranei865 – 883HelicalSequence analysisAdd BLAST19
Transmembranei889 – 909HelicalSequence analysisAdd BLAST21
Transmembranei976 – 995HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi30611.ENSOGAP00000002068

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini393 – 520Guanylate cyclaseInterPro annotationAdd BLAST128
Domaini1057 – 1197Guanylate cyclaseInterPro annotationAdd BLAST141

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3618 Eukaryota
COG2114 LUCA
GeneTreeiENSGT00760000119042
InParanoidiH0WKH0
OMAiLNQSAIS
OrthoDBiEOG091G0285
TreeFamiTF313845

Family and domain databases

CDDicd06174 MFS, 1 hit
Gene3Di3.30.70.1230, 2 hits
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR018297 A/G_cyclase_CS
IPR020846 MFS_dom
IPR029787 Nucleotide_cyclase
PfamiView protein in Pfam
PF00211 Guanylate_cyc, 2 hits
SMARTiView protein in SMART
SM00044 CYCc, 2 hits
SUPFAMiSSF55073 SSF55073, 2 hits
PROSITEiView protein in PROSITE
PS00452 GUANYLATE_CYCLASE_1, 2 hits
PS50125 GUANYLATE_CYCLASE_2, 2 hits

Sequencei

Sequence statusi: Complete.

H0WKH0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASPPHQQLL HHHSTEVTCD SSGDSNSVRV KINPKQLSSS HPKHCKYSIS
60 70 80 90 100
SSCSSSGDSG GVPRRVGGGG RLRRQKKLPQ LFERASSRWW DPKFDSVNLE
110 120 130 140 150
EACLERCFPQ TQRRFRYALF YIGFACLLWS IYFSVHMRSK LIVMVAPALC
160 170 180 190 200
FLVVCVGFFL FTFTKLYARH YAWTSLALTL LVFSLTLAAQ FQVLTPLSGR
210 220 230 240 250
VDSSNHTRAV KPTDTCLSQV GSFSMCIEVL FLLYTVMHLP LYLSLFLGVA
260 270 280 290 300
YSVLFETFGY HFRDEDCFPW PAAGALHWEL LSRALLHGCV HAIGIHLFIM
310 320 330 340 350
SQVRSRSTFL KVGQSIMHGK DLEVEKALKE RMIHSVMPRI IADDLMRQGD
360 370 380 390 400
EESENSAKRH ATSSPKNRKK KSSIQKAPIA FRPFKMQQIE EVSILFADIV
410 420 430 440 450
GFTKMSANKS AHALVGLLND LFGRFDRLCE ETKCEKISTL GDCYYCVAGC
460 470 480 490 500
PEPRADHAYC CIEMGLGMIK AIEQFCQEKK EMVNMRVGVH TGTVLCGILG
510 520 530 540 550
MRRFKFDVWS NDVNLANLME QLGVAGKVHI SEATAKYLDD RYEMEDGKVI
560 570 580 590 600
ERLGQSVVAD QLKGLKTYLI SGQRAKESRC SCAEALLSGF EVIDGSQVSS
610 620 630 640 650
GPRGQGTASS GSASDLAQTV RTFDNLKTCP SCGITFAPKS EAGAEGGAVQ
660 670 680 690 700
NGCQDEHKNS TKASGGPNSK TQNGLLSPPQ EEKLTNSQTS LCEILQEKGR
710 720 730 740 750
WAGVSLDQSA LLPLRFKNIR EKTDAHFVDV IKEDSLMKDY FFKPPINQFS
760 770 780 790 800
LNFLDQELER SYRASYQEEV IKNSPVKTFA SATFSSLLDV FLSTTVFLIL
810 820 830 840 850
SITCFLKYGA TAAPPPPAAL AVFGAALLLE MLSLVVSIRM VFFLEDVMAC
860 870 880 890 900
TKRLLEWISG WLPRHCIGAI LVSLPALAVY SHVTSEFETN IHFSTFTGSA
910 920 930 940 950
ALIAVVHYCN FCQLSSWMRS SLATVVGAGP LLLLYVSLCP DSSMVTSPLD
960 970 980 990 1000
ALQNFSSGRN LCNSSLPRDL RRPASLIGQE VILVFFLLLL LVWFLNREFE
1010 1020 1030 1040 1050
VSYRLHYHGD VEADLHRTKI QSMRDQADWL LRNIIPYHVA EQLKVSQTYS
1060 1070 1080 1090 1100
KNHDSGGVIF ASIVNFGEFY EENYEGGKEC YRVLNELIGD FDELLSKPDY
1110 1120 1130 1140 1150
SNVEKIKTIG ATYMAASGLN TAQAQDGSHP QEHLQILFEF AKEMMRVVDD
1160 1170 1180 1190 1200
FNNNMLWFNF KLRVGFNHGP LTAGVIGTTK LLYDIWGDTV NIASRMDTTG
1210 1220 1230 1240 1250
VECRIQVSEE SYRVLSKMGY EFDYRGTVNV KGKGQMKTYL YPKCTDNGVV
1260 1270 1280 1290 1300
PQHQLSISPD IRVQVDGSIG RSPTDEIANL VPSVQYPDKT SLGSDNSTVQ
1310 1320 1330 1340 1350
AKDTYLSSKR PWKESLKAEE KCQFVQTLEE NDCEDMGMEE ANELTKLNVS

KSV
Length:1,353
Mass (Da):150,959
Last modified:February 22, 2012 - v1
Checksum:i4957B037B2BEC90E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAQR03078298 Genomic DNA No translation available.
AAQR03078299 Genomic DNA No translation available.
AAQR03078300 Genomic DNA No translation available.
AAQR03078301 Genomic DNA No translation available.
AAQR03078302 Genomic DNA No translation available.
AAQR03078303 Genomic DNA No translation available.
AAQR03078304 Genomic DNA No translation available.
AAQR03078305 Genomic DNA No translation available.
AAQR03078306 Genomic DNA No translation available.
AAQR03078307 Genomic DNA No translation available.
RefSeqiXP_003790881.1, XM_003790833.2

Genome annotation databases

EnsembliENSOGAT00000002319; ENSOGAP00000002068; ENSOGAG00000002315
GeneIDi100943767

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAQR03078298 Genomic DNA No translation available.
AAQR03078299 Genomic DNA No translation available.
AAQR03078300 Genomic DNA No translation available.
AAQR03078301 Genomic DNA No translation available.
AAQR03078302 Genomic DNA No translation available.
AAQR03078303 Genomic DNA No translation available.
AAQR03078304 Genomic DNA No translation available.
AAQR03078305 Genomic DNA No translation available.
AAQR03078306 Genomic DNA No translation available.
AAQR03078307 Genomic DNA No translation available.
RefSeqiXP_003790881.1, XM_003790833.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi30611.ENSOGAP00000002068

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOGAT00000002319; ENSOGAP00000002068; ENSOGAG00000002315
GeneIDi100943767

Organism-specific databases

CTDi115

Phylogenomic databases

eggNOGiKOG3618 Eukaryota
COG2114 LUCA
GeneTreeiENSGT00760000119042
InParanoidiH0WKH0
OMAiLNQSAIS
OrthoDBiEOG091G0285
TreeFamiTF313845

Family and domain databases

CDDicd06174 MFS, 1 hit
Gene3Di3.30.70.1230, 2 hits
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR018297 A/G_cyclase_CS
IPR020846 MFS_dom
IPR029787 Nucleotide_cyclase
PfamiView protein in Pfam
PF00211 Guanylate_cyc, 2 hits
SMARTiView protein in SMART
SM00044 CYCc, 2 hits
SUPFAMiSSF55073 SSF55073, 2 hits
PROSITEiView protein in PROSITE
PS00452 GUANYLATE_CYCLASE_1, 2 hits
PS50125 GUANYLATE_CYCLASE_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiH0WKH0_OTOGA
AccessioniPrimary (citable) accession number: H0WKH0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: October 10, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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