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Protein
Submitted name:

Thrombospondin 2

Gene

THBS2

Organism
Cavia porcellus (Guinea pig)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Thrombospondin 2Imported
Gene namesi
Name:THBS2Imported
OrganismiCavia porcellus (Guinea pig)Imported
Taxonomic identifieri10141 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaCaviidaeCavia
Proteomesi
  • UP000005447 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSCPOG00000027034

Interactioni

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000017193

Family & Domainsi

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IFQQ Eukaryota
ENOG410XQKE LUCA
GeneTreeiENSGT00850000132273
InParanoidiH0W2K0
OrthoDBiEOG091G00TV
TreeFamiTF324917

Family and domain databases

Gene3Di2.20.100.10, 3 hits
4.10.1080.10, 2 hits
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR024731 EGF_dom
IPR001791 Laminin_G
IPR037349 Thrombospondin
IPR003367 Thrombospondin_3-like_rpt
IPR017897 Thrombospondin_3_rpt
IPR008859 Thrombospondin_C
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf
IPR015455 TSP2
IPR028974 TSP_type-3_rpt
IPR001007 VWF_dom
PANTHERiPTHR10199 PTHR10199, 2 hits
PTHR10199:SF10 PTHR10199:SF10, 2 hits
PfamiView protein in Pfam
PF12947 EGF_3, 1 hit
PF07645 EGF_CA, 1 hit
PF00090 TSP_1, 3 hits
PF02412 TSP_3, 7 hits
PF05735 TSP_C, 1 hit
PF00093 VWC, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 3 hits
SM00179 EGF_CA, 2 hits
SM00209 TSP1, 3 hits
SM00210 TSPN, 1 hit
SM00214 VWC, 1 hit
SUPFAMiSSF103647 SSF103647, 3 hits
SSF49899 SSF49899, 2 hits
SSF82895 SSF82895, 3 hits
PROSITEiView protein in PROSITE
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 2 hits
PS50092 TSP1, 3 hits
PS51234 TSP3, 8 hits
PS51236 TSP_CTER, 1 hit
PS01208 VWFC_1, 1 hit
PS50184 VWFC_2, 1 hit

Sequencei

Sequence statusi: Complete.

H0W2K0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLWGLSLWAL CAWAGAFAGE QDEDTVFDLF SISNINRKTI GAKQFRGPDP
60 70 80 90 100
GGPAYRFVRF DYIPPVNAAE LDRIIGAMRR KDGFFLTAQL KQDRRSRGTL
110 120 130 140 150
LALEGPGASQ RQFEIVSNGP ADTLDLTYWV EDTEHVVSLE DVGLADSQWK
160 170 180 190 200
NITVQVASET YSLYVGCDLM DSFSLDEPFY EQLEAERSRM YVAKGASRES
210 220 230 240 250
HFRGLLQNVH LVFENSVEDV LRRKGCQQGQ GAEVNAISEH TETLHLSPHI
260 270 280 290 300
TTELVGHGVD QRPEVCEHSC EELANMMREL SGLHVLVRQL DDNLRKVSSD
310 320 330 340 350
NQFLWELIGG PPKTKNMSAC WQDGRFFAEN ETWVVDSCTT CTCKKFKTIC
360 370 380 390 400
HQISCPPVTC AHPSFAEGQC CPTCSHEVDS EEGWSPWSEW TECSVTCGSG
410 420 430 440 450
TQQRGRSCDV TSNTCLGPSI QTRTCSLGKC DPRIRQNGGW SHWSPWSSCS
460 470 480 490 500
VTCGIGNITR IRLCNSPVPQ MGGKNCKGSG RETKTCEGPP CPIDGRWSPW
510 520 530 540 550
SPWSTCTVTC GGGIRERTRA CNNPEPQHGG KDCVGDVKEY HMCNRRSCPI
560 570 580 590 600
DGCLSNPCFP GAACNSFPDG SWSCGSCPVG FVGNGTHCED LDECAVVADI
610 620 630 640 650
CFSTNKASRC INTQPGFHCL PCPPRYKGTQ PFAVGLEAAK TEKQVCEPEN
660 670 680 690 700
PCKDKTHNCH RHAECIYLGH FSDPMYKCEC QIGYAGDGLI CGEDSDLDGW
710 720 730 740 750
PNSNLVCATN ATYHCIKDNC PQLPNSGQED FDKDGVGDAC DEDDDNDGVR
760 770 780 790 800
DEKDNCQLLF NPRQSDYDKD EVGDRCDNCP YVHNPAQIDT DSNGEGDACS
810 820 830 840 850
VDIDGDDVFN ERDNCPYVYN TDQRDTDGDG VGDHCDNCPL MHNPDQTDLD
860 870 880 890 900
NDLVGDQCDN NEDIDDDGHQ NNQDNCPYIS NANQADHDND GKGDACDPDD
910 920 930 940 950
DNDGIPDDRD NCRLVSNPDQ EDSDGDGRGD ICKEDFDNDN VPDIDDVCPE
960 970 980 990 1000
NNAISETDFR NFQMVPLDPK GTTQIDPNWV IRHQGKELVQ TANSDPGIAV
1010 1020 1030 1040 1050
GFDEFGSVDF SGTFYVNTDR DDDYAGFVFG YQSSSRFYVV MWKQVTQTYW
1060 1070 1080 1090 1100
EDQPSRAYGY SGVSLKVVNS TTGTGEHLRN ALWHTGNTEG QVRTLWHDPK
1110 1120 1130 1140 1150
NIGWKDYTAY RWHLIHRPKT GYMRVLVYEG KQVMADSGPI YDQTYSGGRL
1160 1170
GLFVFSQEMV YFSDLKYECR DV
Length:1,172
Mass (Da):130,258
Last modified:November 22, 2017 - v2
Checksum:iABF8E3D048F3191F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAKN02043524 Genomic DNA No translation available.
RefSeqiXP_003466509.2, XM_003466461.3
XP_013004430.1, XM_013148976.1

Genome annotation databases

EnsembliENSCPOT00000023164; ENSCPOP00000017193; ENSCPOG00000027034
GeneIDi100735538

Similar proteinsi

Entry informationi

Entry nameiH0W2K0_CAVPO
AccessioniPrimary (citable) accession number: H0W2K0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: November 22, 2017
Last modified: July 18, 2018
This is version 50 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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