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Protein
Submitted name:

Rho guanine nucleotide exchange factor 40

Gene

ARHGEF40

Organism
Cavia porcellus (Guinea pig)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Rho guanine nucleotide exchange factor 40Imported
Gene namesi
Name:ARHGEF40Imported
OrganismiCavia porcellus (Guinea pig)Imported
Taxonomic identifieri10141 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaCaviidaeCavia
Proteomesi
  • UP000005447 Componenti: Unassembled WGS sequence

Expressioni

Gene expression databases

BgeeiENSCPOG00000012862

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000011576

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili690 – 710Sequence analysisAdd BLAST21
Coiled coili771 – 791Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0689 Eukaryota
ENOG410XSWY LUCA
GeneTreeiENSGT00920000149030
InParanoidiH0VME8
OrthoDBiEOG091G016I
TreeFamiTF334329

Family and domain databases

Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
PfamiView protein in Pfam
PF00621 RhoGEF, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
PROSITEiView protein in PROSITE
PS50010 DH_2, 1 hit
PS50003 PH_DOMAIN, 1 hit

Sequencei

Sequence statusi: Complete.

H0VME8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPEPVEDCV QSTLAALYPP FEATAPTLLG QVFQVVERTY REDALRYTLD
60 70 80 90 100
FLVPAKHLLA KVQQEACAQY SGFLFFHEGW PLCLHEQVVV QLAALPWQLL
110 120 130 140 150
RPGDFYLQVV PSAAQAPHLA LKCLAPGGGR VQELPVPSEA CAYLFTPEWL
160 170 180 190 200
QGINKDRPTG RLSTCLLSAP SGIQRLPWAE LICPRFVHKG GLMVGHRPGT
210 220 230 240 250
LPPELPSVPP GLPSPPLSEE VLGTRSPGDG HNAPAEGPEG EYVELLEVTL
260 270 280 290 300
PVRGSPTDAE GSSDLARTRT VPTRKSAGGK GRHRRHRAWM HQKGLGVRAQ
310 320 330 340 350
HQDGSRPPGE GSSTGASPGS PLGAEAVPEA VDAEVSEPPT EASGEASESC
360 370 380 390 400
LLRSGDPGAG QGAEGPPGTP RRTGKGNRRK KRAAGRGALS RGGDSAPLSL
410 420 430 440 450
GDKEETGHHG ALVSLPSPNE NKLPACSLVK DGNKGSENSE SEAKEELTSP
460 470 480 490 500
DEKETLPPEN YGSPEEGTRE RQQKGSSLVC VAASAGSEGL LSDPPTQPLE
510 520 530 540 550
PLQEVKVESI PEEPPPVSIS ADSDIAWELM ASGFLVLTGG LDQSGRALLT
560 570 580 590 600
ITPPCPPEEP PPSQDMLSTV LHYLHSLLRP DLQLLGLSVL LDLRKAPPLP
610 620 630 640 650
PALVPALSQL QDSGDPHLIQ RLLILTNDDP PTELCGFQGA EWVSENDLKR
660 670 680 690 700
VAKPEELQWD LGGHRDPSPS YWVEIHKEVA RLCSLCQGVL SSVRQAIEEL
710 720 730 740 750
ERAAESEGEE AVGMPEPLQK VLADHRLTAL QRDGGAILMR LRSTHSSKLE
760 770 780 790 800
GPGPATLYQE VDEAIHQLVR LSNLQVQRQE HRQRLRHLQQ VLQWLSGPGE
810 820 830 840 850
EQLASFAMPG DSLPALQETE LRFRAFHTEV QEHLAQAREA LALQEDPASQ
860 870 880 890 900
KVLDIFEQRL EQVESGLHRA LRLQRFFQQA HEWVDEGSAR LAGAGPGREA
910 920 930 940 950
LLAALALRRA PEPSAGTFQE MRALALDLGS PAALREWGRC HARCQELERR
960 970 980 990 1000
IQQQLGEEAS PRGHRRRRAD SASSAGTQRG SHSPSPSLSS LLLPGSPGLR
1010 1020 1030 1040 1050
AAPSHCSLAP CGEDCEEEAP ELAPETEGKP PRSVLIRGLE VTSTEVVDRT
1060 1070 1080 1090 1100
CSPREHVLLG RAGGPDGPWG LGTPRMERKR SISTQQRLVS ELIACEQEYV
1110 1120 1130 1140 1150
TSLSEPVPPP GPELTPELRG TWAAVLSTRE RLRSFHRTHF LRELQGCATY
1160 1170 1180 1190 1200
PLRIGACFLR HGDQFGLYAQ YVKHRHKLEN CLAALNPPSK GSTEGGPYLP
1210 1220 1230 1240 1250
LALQQPLEQL TRYGRLLEDL LREAGPEPSS ERQALGAAVQ LLQEQEARGR
1260 1270 1280 1290 1300
DLLAVEAVRG CEIDLKEQGQ LLHRDPFTVI CGRKKCLRHV FLFEHLLLFS
1310 1320 1330 1340 1350
KLKGSEGGSE TFVYKQAFKT ADMGLTENIG DSGLCFELWF RRRRAREAYT
1360 1370 1380 1390 1400
LQATSPEIKL KWTSSIAQLL WRQAAHNKEL RVQQMVSMGI GNKPFLDIKA
1410 1420 1430 1440 1450
LGERTLSALL TGRAARTRAS VAVSSFEHAG PSLPGLSPGA CSLPARVEEE
1460 1470 1480 1490 1500
AWDLDVKQIS LAPETLDSSG DVSPGPRNSP SVPPPHPGSS TPTLASGGIL
1510
GLSWQSHARA LSDPTTPL
Length:1,518
Mass (Da):164,692
Last modified:November 22, 2017 - v2
Checksum:i9FF7A4C36D5DA4E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAKN02019190 Genomic DNA No translation available.
RefSeqiXP_003474387.2, XM_003474339.3
XP_013012894.1, XM_013157440.1
XP_013012895.1, XM_013157441.1

Genome annotation databases

EnsembliENSCPOT00000012987; ENSCPOP00000011576; ENSCPOG00000012862
GeneIDi100720080

Similar proteinsi

Entry informationi

Entry nameiH0VME8_CAVPO
AccessioniPrimary (citable) accession number: H0VME8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: November 22, 2017
Last modified: June 20, 2018
This is version 43 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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