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Protein

Palmitoyltransferase

Gene

ZDHHC17

Organism
Cavia porcellus (Guinea pig)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotationSAAS annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:ZDHHC17Imported
OrganismiCavia porcellus (Guinea pig)Imported
Taxonomic identifieri10141 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaCaviidaeCavia
Proteomesi
  • UP000005447 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSCPOG00000012534 Expressed in 3 organ(s), highest expression level in brain

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000011278

Family & Domainsi

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotationSAAS annotation

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0509 Eukaryota
COG0666 LUCA
COG5273 LUCA
GeneTreeiENSGT00530000063074
InParanoidiH0VLN3
OrthoDBiEOG091G056H
TreeFamiTF317342

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR001594 Palmitoyltrfase_DHHC
IPR030289 ZDHHC17
PANTHERiPTHR24161:SF18 PTHR24161:SF18, 1 hit
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF01529 DHHC, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 5 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 5 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

H0VLN3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
EIKPQSHYNH GYGEPLGRKT HIDDYSTWDI VKATQYGIYE RCRELVEAGY
60 70 80 90 100
DVRQPDKENV TLLHWAAINN RIDLVKYYIS KGAIVDQLGG DLNSTPLHWA
110 120 130 140 150
TRQGHLSMVV QLMKYGADPS LIDGEGCSCI HLAAQFGHTS IVAYLIAKGQ
160 170 180 190 200
DVDMMDQNGM TPLMWAAYRT HSVDPTRLLL TFNVSVNLGD KYHKNTALHW
210 220 230 240 250
AVLAGNTTVI SLLLEAGANV DAQNIKGESA LDLAKQRKNV WMINHLQEAR
260 270 280 290 300
QAKGYDNPSF LRKLKADKEF RQKVMLGTPF LVIWLVGFIA DLNIDSWLIK
310 320 330 340 350
GLMYGGVWAT VQFLSKSFFD HSMHSALPLG IYLATKFWMY VTWFFWFWND
360 370 380 390 400
LNFLFIHLPF LANSVALFYN FGKSWKSDPG IIKATEEQKK KTIVELAETG
410 420 430 440 450
SLDLSIFCST CLIRKPVRSK HCGVCNRCIA KFDHHCPWVG NCVGAGNHRY
460 470 480 490 500
FMGYLFFLLF MICWMIYGCI SYWGLHCETT YTKDGFWTYI TQIATCSPWM
510 520 530 540 550
FWMFLNSVFH FMWVAVLLMC QMYQISCLGI TTNERMNARR YKHFKVTTTS
560 570 580 590 600
IESPFNHGCV RNIIDFFEFR CCGLFRPVIV DWTRQYTIEY DQISGSGYQL

V
Length:601
Mass (Da):69,177
Last modified:November 22, 2017 - v2
Checksum:i40C047CDF54155A8
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A286XH87A0A286XH87_CAVPO
Uncharacterized protein
ZDHHC17
235Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAKN02014304 Genomic DNA No translation available.
AAKN02014305 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSCPOT00000012654; ENSCPOP00000011278; ENSCPOG00000012534

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAKN02014304 Genomic DNA No translation available.
AAKN02014305 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000011278

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCPOT00000012654; ENSCPOP00000011278; ENSCPOG00000012534

Phylogenomic databases

eggNOGiKOG0509 Eukaryota
COG0666 LUCA
COG5273 LUCA
GeneTreeiENSGT00530000063074
InParanoidiH0VLN3
OrthoDBiEOG091G056H
TreeFamiTF317342

Gene expression databases

BgeeiENSCPOG00000012534 Expressed in 3 organ(s), highest expression level in brain

Family and domain databases

CDDicd00204 ANK, 2 hits
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR001594 Palmitoyltrfase_DHHC
IPR030289 ZDHHC17
PANTHERiPTHR24161:SF18 PTHR24161:SF18, 1 hit
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF01529 DHHC, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 5 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 5 hits
ProtoNetiSearch...

Entry informationi

Entry nameiH0VLN3_CAVPO
AccessioniPrimary (citable) accession number: H0VLN3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: November 22, 2017
Last modified: September 12, 2018
This is version 51 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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