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Protein

Tetraspanin

Gene

CD53

Organism
Cavia porcellus (Guinea pig)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
TetraspaninUniRule annotation
Gene namesi
Name:CD53Imported
OrganismiCavia porcellus (Guinea pig)Imported
Taxonomic identifieri10141 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricomorphaCaviidaeCavia
Proteomesi
  • UP000005447 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 35HelicalUniRule annotationAdd BLAST24
Transmembranei47 – 69HelicalUniRule annotationAdd BLAST23
Transmembranei81 – 105HelicalUniRule annotationAdd BLAST25
Transmembranei182 – 206HelicalUniRule annotationAdd BLAST25

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSCPOG00000010280

Interactioni

Protein-protein interaction databases

STRINGi10141.ENSCPOP00000009230

Family & Domainsi

Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3882 Eukaryota
ENOG4111IRY LUCA
GeneTreeiENSGT00880000137858
InParanoidiH0VGI8
OMAiVCVIQVL
OrthoDBiEOG091G0CQO
TreeFamiTF352892

Family and domain databases

Gene3Di1.10.1450.10, 1 hit
InterProiView protein in InterPro
IPR000301 Tetraspanin
IPR018499 Tetraspanin/Peripherin
IPR018503 Tetraspanin_CS
IPR008952 Tetraspanin_EC2_sf
PfamiView protein in Pfam
PF00335 Tetraspannin, 1 hit
PIRSFiPIRSF002419 Tetraspanin, 1 hit
PRINTSiPR00259 TMFOUR
SUPFAMiSSF48652 SSF48652, 1 hit
PROSITEiView protein in PROSITE
PS00421 TM4_1, 1 hit

Sequencei

Sequence statusi: Complete.

H0VGI8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGMSSLKLLK YVLFFFNLLF WLCGCCILGF GIYFLVHNDF GVLFHKLPFL
60 70 80 90 100
TLGNILVIVG SIIMVVAFLG CMGSIKENKC LLMSFFVLLL IILLAEVTLA
110 120 130 140 150
ILLFVHEQKL NSYVAEGLTE SIHRYYLDNS TKAAWDSIQS FLHCCGVNQT
160 170 180 190 200
SDWSGHPPAS CPSEQGVKGC YMKTQEWFHS NFLYIGIIII CICMIQVLGM
210
SFALTLNCQI DKTSQAIGL
Length:219
Mass (Da):24,522
Last modified:February 22, 2012 - v1
Checksum:i329CD505551CA6BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAKN02004557 Genomic DNA No translation available.
AAKN02004558 Genomic DNA No translation available.
RefSeqiXP_003479272.1, XM_003479224.3

Genome annotation databases

EnsembliENSCPOT00000010374; ENSCPOP00000009230; ENSCPOG00000010280
GeneIDi100735881

Similar proteinsi

Entry informationi

Entry nameiH0VGI8_CAVPO
AccessioniPrimary (citable) accession number: H0VGI8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: March 28, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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