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Entry version 56 (18 Sep 2019)
Sequence version 1 (22 Feb 2012)
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Protein
Submitted name:

FI18026p1

Gene

asp-RA

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FI18026p1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:asp-RAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
H0RNM3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0000140 Expressed in 26 organ(s), highest expression level in egg chamber

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
H0RNM3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
H0RNM3 DM

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
H0RNM3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini836 – 968Calponin-homology (CH)InterPro annotationAdd BLAST133

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni134 – 155DisorderedSequence analysisAdd BLAST22
Regioni476 – 548DisorderedSequence analysisAdd BLAST73

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1160 – 1180Sequence analysisAdd BLAST21
Coiled coili1619 – 1639Sequence analysisAdd BLAST21
Coiled coili1715 – 1735Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi529 – 546PolarSequence analysisAdd BLAST18

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0165 Eukaryota
ENOG410XSAR LUCA

KEGG Orthology (KO)

More...
KOi
K16743

Identification of Orthologs from Complete Genome Data

More...
OMAi
HLDVVMQ

Database of Orthologous Groups

More...
OrthoDBi
482623at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
H0RNM3

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014 CH, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031549 ASH
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR000048 IQ_motif_EF-hand-BS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15780 ASH, 1 hit
PF00307 CH, 1 hit
PF00612 IQ, 7 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033 CH, 1 hit
SM00015 IQ, 16 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576 SSF47576, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50021 CH, 1 hit
PS50096 IQ, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H0RNM3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAFEITVTP SRLKQKKRAE GREPAVVVMA PFSAKAIVQF EDVPITKTAR
60 70 80 90 100
RQVRVLNPSD DDIEVKVMKA IREEHNLSLE WMEHTVPARD EVSMELVWSP
110 120 130 140 150
VLEVACKETL QLIDNRNFRK EVMIILKSKS NQPVKNPRKF PTVGKTLQLK
160 170 180 190 200
SPTGAGKTMK SVVSAAVQQK KRMSAAAAPP SKQTWRVTAP SRPAAWAHPP
210 220 230 240 250
PQAPLVEKNV YKTPQEEPVY ISPQPRSLKE NLSPMTPGNL LDVIDNLRFT
260 270 280 290 300
PLTETRGKGQ ATIFPDNLAA WPTPTLKGNV KSCANDMRPR RITPDDLEDQ
310 320 330 340 350
PATNKTFDVK HSETINISLD TLDCSRIDGQ PHTPLNKTTT IVHATHTRAL
360 370 380 390 400
ACIHEEEGPS PPRTPTKSAI HDLKRDIKLV GSPLRKYSES MKDLSLLSPQ
410 420 430 440 450
TKYAIQGSMP NLNEMKIRSI EQNRYYQEQQ IQIKAKDLNS SSSSEASLAG
460 470 480 490 500
QQEFLFNHSE ILAQSSRFNL HEVGRKSVKG SPVKNPHKRR SHELSFSDAP
510 520 530 540 550
SNESLYRNET VAISPPKKQR VEDTTLPRSA APANASARSS SAHAWPHAQS
560 570 580 590 600
KKFKLAQTMS LMKKPATPRK VRDTSIQPSV KLYDSELYMQ TCINPDPFAA
610 620 630 640 650
TTTIDPFLAS TMYLDEQAVD RHQADFKKWL NALVSIPADL DADLNNKIDV
660 670 680 690 700
GKLFNEVRNK ELVVAPTKEE QSMNYLTKYR LETLRKAAVE LFFSEQMRLP
710 720 730 740 750
CSKVAVYVNK QALRIRSDRN LHLDVVMQRT ILELLLCFNP LWLRLGLEVV
760 770 780 790 800
FGEKIQMQSN RDIVGLSTFI LNRLFRNKCE EQRYSKAYTL TEEYAETIKK
810 820 830 840 850
HSLQKILFLL LFLDQAKQKR IVKHNPCLFV KKSPHKETKD ILLRFSSELL
860 870 880 890 900
ANIGDITREL RRLGYVLQHR QTFLDEFDYA FNNLAVDLRD GVRLTRVMEV
910 920 930 940 950
ILLRDDLTRQ LRVPAISRLQ RIFNVKLALG ALGEANFQLG GDIAAQDIVD
960 970 980 990 1000
GHREKTLSLL WQLIYKFRSP KFHAAATVLQ KWWRRHWLHV VIQRRIRHKE
1010 1020 1030 1040 1050
LMRRHRAATV IQAVFRGHQM RKYVKLFKTE RTQAAIILQK FTRRYLAQKQ
1060 1070 1080 1090 1100
LYQSYHSIIT IQRWWRAQQL GRQHRQRFVE LREAAIFLQR IWRRRLFAKK
1110 1120 1130 1140 1150
LLAAAETARL QRSQKQQAAA SYIQMQWRSY QLGRIQRQQF LRQRDLIMFV
1160 1170 1180 1190 1200
QRRMRSKWSM LEQRKEFQQL KRAAINIQQR WRAKLSMRKC NADYLALRSS
1210 1220 1230 1240 1250
VLKVQAYRKA TIQMRIDRNH YYSLRKNVIC LQQRLRAIMK MREQRENYLR
1260 1270 1280 1290 1300
LRNASILVQK RYRMRQQMIQ DRNAYLRTRK CIINVQRRWR ATLQMRRERK
1310 1320 1330 1340 1350
NYLHLQTTTK RIQIKFRAKR EMKKQRAEFL QLKKVTLVVQ KRRRALLQMR
1360 1370 1380 1390 1400
KERQEYLHLR EVTIKLQRRF HAQKSMRFMR AKYRGTQAAV SCLQMHWRNH
1410 1420 1430 1440 1450
LLRKRERNSF LQLRQAAITL QRRYRARLNM IKQLKSYAQL KQAAITIQTR
1460 1470 1480 1490 1500
YRAKKAMQKQ VVLYQKQREA IIKVQRRYRG NLEMRKQIEV YQKQRQAVIR
1510 1520 1530 1540 1550
LQKWWRSIRD MRLCKAGYRR IRLSSLSIQR KWRATVQARR QREIFLSTIR
1560 1570 1580 1590 1600
KVRLMQAFIR ATLLMRQQRR EFEMKRRAAV VIQRRFRARC AMLKARQDYQ
1610 1620 1630 1640 1650
LIQSSVILVQ RKFRANRSMK QARQEFVQLR TIAVHLQQKF RGKRLMIEQR
1660 1670 1680 1690 1700
NCFQLLRCSM PGFQARARGF MARKRFQALM TPEMMDLIRQ KRAAKVIQRY
1710 1720 1730 1740 1750
WRGYLIRRRQ KHQGLLDIRK RIAQLRQEAK AVNSVRCKVQ EAVRFLRGRF
1760 1770 1780 1790 1800
IASDALAVLS RLDRLSRTVP HLLMWCSEFM STFCYGIMAQ AIRSEVDKQL
1810 1820 1830 1840 1850
IERCSRIILN LARYNSTTVN TFQEGGLVTI AQMLLRWCDK DSEIFNTLCT
1860 1870 1880 1890 1900
LIWVFAHCPK KRKIIHDYMT NPEAIYMVRE TKKLVARKEK MKQNARKPPP
1910 1920 1930 1940 1950
MTSGRYKSQK INFTPCSLPS LEPDFGIIRY SPYTFISSVY AFDTILCKLQ

IDMF
Length:1,954
Mass (Da):230,180
Last modified:February 22, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4912B4E20CA9E659
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BT132945 mRNA Translation: AEW31264.1

NCBI Reference Sequences

More...
RefSeqi
NP_524488.3, NM_079764.3

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
42946

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG6875

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT132945 mRNA Translation: AEW31264.1
RefSeqiNP_524488.3, NM_079764.3

3D structure databases

SMRiH0RNM3
ModBaseiSearch...

Proteomic databases

PRIDEiH0RNM3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi42946
KEGGidme:Dmel_CG6875

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
42946

Phylogenomic databases

eggNOGiKOG0165 Eukaryota
ENOG410XSAR LUCA
KOiK16743
OMAiHLDVVMQ
OrthoDBi482623at2759
PhylomeDBiH0RNM3

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
42946

Gene expression databases

BgeeiFBgn0000140 Expressed in 26 organ(s), highest expression level in egg chamber
ExpressionAtlasiH0RNM3 baseline and differential
GenevisibleiH0RNM3 DM

Family and domain databases

CDDicd00014 CH, 1 hit
Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR031549 ASH
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR000048 IQ_motif_EF-hand-BS
PfamiView protein in Pfam
PF15780 ASH, 1 hit
PF00307 CH, 1 hit
PF00612 IQ, 7 hits
SMARTiView protein in SMART
SM00033 CH, 1 hit
SM00015 IQ, 16 hits
SUPFAMiSSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
PS50096 IQ, 5 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH0RNM3_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H0RNM3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: September 18, 2019
This is version 56 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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