Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 38 (16 Jan 2019)
Sequence version 1 (22 Feb 2012)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Putative Bifunctional P-450:NADPH-P450 reductase

Gene

M7I_2161

Organism
Glarea lozoyensis (strain ATCC 74030 / MF5533)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandHemeSAAS annotation, Iron, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative Bifunctional P-450:NADPH-P450 reductaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:M7I_2161Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGlarea lozoyensis (strain ATCC 74030 / MF5533)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1104152 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaLeotiomycetesHelotialesHelotiaceaeGlarea

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini496 – 633Flavodoxin-likeInterPro annotationAdd BLAST138
Domaini670 – 909FAD-binding FR-typeInterPro annotationAdd BLAST240

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
H0EI16

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1280.10, 1 hit
1.10.630.10, 1 hit
1.20.990.10, 1 hit
3.40.50.360, 1 hit
3.40.50.80, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003097 CysJ-like_FAD-binding
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR036396 Cyt_P450_sf
IPR017927 FAD-bd_FR_type
IPR001094 Flavdoxin-like
IPR008254 Flavodoxin/NO_synth
IPR001709 Flavoprot_Pyr_Nucl_cyt_Rdtase
IPR029039 Flavoprotein-like_sf
IPR039261 FNR_nucleotide-bd
IPR023173 NADPH_Cyt_P450_Rdtase_alpha
IPR001433 OxRdtase_FAD/NAD-bd
IPR017938 Riboflavin_synthase-like_b-brl
IPR002227 Tyrosinase_Cu-bd
IPR008922 Unchr_di-copper_centre

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00667 FAD_binding_1, 1 hit
PF00258 Flavodoxin_1, 1 hit
PF00175 NAD_binding_1, 1 hit
PF00067 p450, 2 hits
PF00264 Tyrosinase, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00369 FLAVODOXIN
PR00371 FPNCR
PR00092 TYROSINASE

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48056 SSF48056, 1 hit
SSF48264 SSF48264, 1 hit
SSF52218 SSF52218, 1 hit
SSF52343 SSF52343, 1 hit
SSF63380 SSF63380, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit
PS51384 FAD_FR, 1 hit
PS50902 FLAVODOXIN_LIKE, 1 hit
PS00498 TYROSINASE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

H0EI16-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSQCPFDDG SGIAPHPMPP QLETPIQQLP IPQPPTHLFG LLGNIPEMDP
60 70 80 90 100
SFPARSFWRL NQLYGPIVKL SLKTPTILLS SQEFVNEVCD ESRFEKYPGS
110 120 130 140 150
LLVEVRPLLG DGLFTAFPDE KAWGIAHRTL MPVFGPMGVR KMFDGMLDIA
160 170 180 190 200
CQMVLRWDRL GPDHEIECSD DLTRLVADVL IESGKRGSRP SLLNKFYLKD
210 220 230 240 250
ERIRQENVRK MHDLADQILA ERKAHPKPDA NDLLNTMIYA VDSVTGEKLT
260 270 280 290 300
DEMIRYNMCT FLVAGHETTS STLSFTYYNL LNNPEKLHKA QQEVDEVLGD
310 320 330 340 350
SIMTVDHIPK FKYIDACLKE TLRLSSPING ISVKPKQDTT LGGGRYTVSR
360 370 380 390 400
EDFISVNMKG LHHDVKVWGE DHDEFKPERM FDDKFNALPP NSWKPFGNGA
410 420 430 440 450
RGCIGRGFAW QEMLMNVALV LQRFQIEKAD PNYKLELKST LTIKPWNWRM
460 470 480 490 500
KVRRRPGKAL MTGIPGGIPS EVAQKSKATS ENAQDSTGSE AKAAKFTIFF
510 520 530 540 550
GGNADTCEGM AQDLQSRAQA HGLEGEIQAL DSATENLPTD RPIVIITSSY
560 570 580 590 600
EGKPPDNAKK FVSWLETKSD VSLLKDVKYA VFGVGNSDWV DTYHRIPRVV
610 620 630 640 650
DEGLKRLGAQ RLCDTGFSNV KEDLIGPWEE FLDPLIESLR KAVGASGDVL
660 670 680 690 700
TKELAVDIQT SKDPKIPPRD ESAFGTVLVN RELASNEIGP AKKHMEIRLP
710 720 730 740 750
ALEGAEHYTA GDYLVVTPRN PKIVVERVIS HFDLKEDQNI SFKNSKKFFL
760 770 780 790 800
PTTPISVKEF LFTAVELSTP ITKKQVETVV ASAKQEQKSK IEILRDAEVY
810 820 830 840 850
QGLLKRRYSI LDILDEYDVD IPLSTYVDML QPLAARQYSI SSSALYPDNN
860 870 880 890 900
PGNEEHADIL SITYDVLEQP ALSGNGTFYG VASTYLASRR PGDRIACATR
910 920 930 940 950
STNVNFRLPK DPETPVIMIA AGTGIAPMRA FIQERAAIAE AGARKLGPAI
960 970 980 990 1000
LFFGCRHADK DFIYKDELSK WESEGIVEVK PAFSKMSDKP VYVQDVIWEN
1010 1020 1030 1040 1050
REKARTMFQA GGKIFLCGSA SKLGKSAADI CKKIYREGKN CSEEEAAEWL
1060 1070 1080 1090 1100
DRQKEDRYVS DVFVHEESLP DGLATFHVCS IMGIIGLFHL MYFDRLRNIE
1110 1120 1130 1140 1150
IYIDELANSG HLEATLFIAV STISRMQVRG WSVLLAATVI DVASAKFALT
1160 1170 1180 1190 1200
GVFTGVDAKT GYRPPRREIE DLAGDVKQFS LYVQAVNAMM KTDERELTSY
1210 1220 1230 1240 1250
FQIGGIHGLP YISWDGVNPS RSNQGSKNTG YCTHGNTLFG TWHRPYMAIF
1260 1270 1280 1290 1300
EQIMAQKAQA IAKTYTSDKA AWQTAADKLR SPFWDWAAPP VHFPAVLKAQ
1310 1320 1330 1340 1350
TVQITTPTGV KSVSNPLYSY KFLNNPEINN WFPSDYLGTQ KRTLRYPNQA
1360 1370 1380 1390 1400
TNTSNDDFDD RAVAEDPTTS GVWNVFSKTS NFNEMSTSST GGYTFEGPHS
1410 1420 1430 1440 1450
TIHIIIGGGG HFSPPDYAAF DPLFYLHHGN VDRQIAMWQA IYPNSYLTPA
1460 1470 1480 1490 1500
NTTSGTWTIT VGDVLDENTA LTPFTQGDGR TPWTSKAARQ IKTFGYSYPD
1510 1520 1530 1540 1550
VPDWLFTNPR ALAANVTARV NKLYNADGSL GPFGTKIKGR AAPASDTLSW
1560 1570 1580 1590 1600
SIAAKVANSI LDEPFSVKLT VGDVRVGRLS VLIASTTENL EASTFGEFEL
1610 1620 1630 1640 1650
SAALKDVDVT DVDAVVTKLK GSVKYTVVKA DGTTVDGAKA ELSVSSQVVT
1660 1670
PAKDVTEFPV FGERKEHPGI FTN
Length:1,673
Mass (Da):185,715
Last modified:February 22, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC525D0E6280C90F7
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AGUE01000044 Genomic DNA Translation: EHL01809.1

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGUE01000044 Genomic DNA Translation: EHL01809.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

InParanoidiH0EI16

Family and domain databases

Gene3Di1.10.1280.10, 1 hit
1.10.630.10, 1 hit
1.20.990.10, 1 hit
3.40.50.360, 1 hit
3.40.50.80, 1 hit
InterProiView protein in InterPro
IPR003097 CysJ-like_FAD-binding
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR036396 Cyt_P450_sf
IPR017927 FAD-bd_FR_type
IPR001094 Flavdoxin-like
IPR008254 Flavodoxin/NO_synth
IPR001709 Flavoprot_Pyr_Nucl_cyt_Rdtase
IPR029039 Flavoprotein-like_sf
IPR039261 FNR_nucleotide-bd
IPR023173 NADPH_Cyt_P450_Rdtase_alpha
IPR001433 OxRdtase_FAD/NAD-bd
IPR017938 Riboflavin_synthase-like_b-brl
IPR002227 Tyrosinase_Cu-bd
IPR008922 Unchr_di-copper_centre
PfamiView protein in Pfam
PF00667 FAD_binding_1, 1 hit
PF00258 Flavodoxin_1, 1 hit
PF00175 NAD_binding_1, 1 hit
PF00067 p450, 2 hits
PF00264 Tyrosinase, 1 hit
PRINTSiPR00369 FLAVODOXIN
PR00371 FPNCR
PR00092 TYROSINASE
SUPFAMiSSF48056 SSF48056, 1 hit
SSF48264 SSF48264, 1 hit
SSF52218 SSF52218, 1 hit
SSF52343 SSF52343, 1 hit
SSF63380 SSF63380, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit
PS51384 FAD_FR, 1 hit
PS50902 FLAVODOXIN_LIKE, 1 hit
PS00498 TYROSINASE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiH0EI16_GLAL7
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: H0EI16
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: January 16, 2019
This is version 38 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again