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Protein

Cytochrome b

Gene

CYTB

Organism
Leucoraja erinacea (Little skate) (Raja erinacea)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.UniRule annotation

Cofactori

hemeUniRule annotationNote: Binds 2 heme groups non-covalently.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Respiratory chainUniRule annotation, Transport
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome bUniRule annotation
Gene namesi
Name:CYTBImported
Encoded oniMitochondrionImported
OrganismiLeucoraja erinacea (Little skate) (Raja erinacea)Imported
Taxonomic identifieri7782 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiBatoideaRajiformesRajidaeLeucoraja

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei31 – 53HelicalUniRule annotationAdd BLAST23
Transmembranei88 – 108HelicalUniRule annotationAdd BLAST21
Transmembranei114 – 134HelicalUniRule annotationAdd BLAST21
Transmembranei146 – 167HelicalUniRule annotationAdd BLAST22
Transmembranei179 – 201HelicalUniRule annotationAdd BLAST23
Transmembranei230 – 251HelicalUniRule annotationAdd BLAST22
Transmembranei289 – 309HelicalUniRule annotationAdd BLAST21
Transmembranei321 – 341HelicalUniRule annotationAdd BLAST21
Transmembranei347 – 373HelicalUniRule annotationAdd BLAST27

Keywords - Cellular componenti

Membrane, MitochondrionUniRule annotationImported

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 210CYTB_NTERInterPro annotationAdd BLAST210
Domaini211 – 380CYTB_CTERInterPro annotationAdd BLAST170

Sequence similaritiesi

Belongs to the cytochrome b family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

CDDicd00290 cytochrome_b_C, 1 hit
cd00284 Cytochrome_b_N, 1 hit
Gene3Di1.20.810.10, 1 hit
InterProiView protein in InterPro
IPR005798 Cyt_b/b6_C
IPR036150 Cyt_b/b6_C_sf
IPR005797 Cyt_b/b6_N
IPR027387 Cytb/b6-like_sf
IPR030689 Cytochrome_b
IPR016174 Di-haem_cyt_TM
PfamiView protein in Pfam
PF00032 Cytochrom_B_C, 1 hit
PF00033 Cytochrome_B, 1 hit
PIRSFiPIRSF038885 COB, 1 hit
SUPFAMiSSF81342 SSF81342, 1 hit
SSF81648 SSF81648, 1 hit
PROSITEiView protein in PROSITE
PS51003 CYTB_CTER, 1 hit
PS51002 CYTB_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

G9L9J1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTNIRKTHP LFKIINSSLI DLPTPINISI WWNYGSLLGL CLIIQILTGL
60 70 80 90 100
FLAMHYTPDI SSAFSSVVHI CRDVNYGWLI RNIHANGASL FFICIYIHIA
110 120 130 140 150
RGFYYGSYLN KETWNIGVIL LFLLMATAFV GYVLPWGQMS FWGATVITNL
160 170 180 190 200
LSAFPYIGNI LVEWIWGGFS VDNATLTRFF AFHFLFPFLI VAFTLLHLIF
210 220 230 240 250
LHEMGSNNPT GLNSNTDKIL FHPYFSYKDL LGFFILMLIL TLLALFAPNL
260 270 280 290 300
LGDTENFIPA DPLLTPPHIK PEWYFLFAYA ILRSIPNKLG GVLALLFSIL
310 320 330 340 350
ILMFVPLLHT SKQRSATFRP ITQILFWTLL TNTIILTWIG GQPVEQPFII
360 370 380
IGQIASIVYF LLFLILLPLA GWWENKILNL
Length:380
Mass (Da):43,305
Last modified:February 22, 2012 - v1
Checksum:i18E70846E9916991
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ034406 Genomic DNA Translation: AET87641.1
RefSeqiYP_004935530.1, NC_016429.1

Genome annotation databases

GeneIDi11452177

Similar proteinsi

Entry informationi

Entry nameiG9L9J1_LEUER
AccessioniPrimary (citable) accession number: G9L9J1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: January 31, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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