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Protein

NADH-ubiquinone oxidoreductase chain 4L

Gene

ND4L

Organism
Leucoraja erinacea (Little skate) (Raja erinacea)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.UniRule annotation

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandNADUniRule annotation, UbiquinoneUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase chain 4LUniRule annotation (EC:1.6.5.3UniRule annotation)
Gene namesi
Name:ND4LImported
Encoded oniMitochondrionImported
OrganismiLeucoraja erinacea (Little skate) (Raja erinacea)Imported
Taxonomic identifieri7782 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiBatoideaRajiformesRajidaeLeucoraja

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 22HelicalSequence analysisAdd BLAST17
Transmembranei29 – 50HelicalSequence analysisAdd BLAST22
Transmembranei56 – 80HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane, MitochondrionUniRule annotationImported

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I subunit 4L family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR001133 NADH_UbQ_OxRdtase_chain4L/K
PANTHERiPTHR11434 PTHR11434, 1 hit

Sequencei

Sequence statusi: Complete.

G9L9I7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTPIYFTITS AFILGLTGLA FNRSHLLSAL ICLEGMMLSL FIAIAIWSMV
60 70 80 90
MSSPSLSLAP MVLLTFSACE ASSGLALLVA ATRTHGTDHL NNLNLLQC
Length:98
Mass (Da):10,446
Last modified:February 22, 2012 - v1
Checksum:i71CC360B66506976
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JQ034406 Genomic DNA Translation: AET87637.1
RefSeqiYP_004935526.1, NC_016429.1

Genome annotation databases

GeneIDi11452186

Similar proteinsi

Entry informationi

Entry nameiG9L9I7_LEUER
AccessioniPrimary (citable) accession number: G9L9I7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 22, 2012
Last sequence update: February 22, 2012
Last modified: June 7, 2017
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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