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UniProtKB - G8C1A6 (G8C1A6_TETPH)

Entry version 41 (10 Feb 2021)
Sequence version 1 (25 Jan 2012)
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Protein

Peptidase S59 domain-containing protein

Gene

TPHA0N01530

Organism
Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA transport, Protein transport, Translocation, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Peptidase S59 domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TPHA0N01530Imported
Ordered Locus Names:TPHA_0N01530Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1071381 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Tetrapisispora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005666 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nuclear pore complexARBA annotation, Nucleus

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		113608.XP_003688368.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini912 – 1054Peptidase S59InterPro annotationAdd BLAST143

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 47DisorderedSequence analysisAdd BLAST47
Regioni258 – 564DisorderedSequence analysisAdd BLAST307

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi24 – 47PolarSequence analysisAdd BLAST24
Compositional biasi258 – 351PolarSequence analysisAdd BLAST94
Compositional biasi358 – 408PolarSequence analysisAdd BLAST51
Compositional biasi420 – 508PolarSequence analysisAdd BLAST89
Compositional biasi531 – 560PolarSequence analysisAdd BLAST30

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the nucleoporin GLFG family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0845, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_011051_0_0_1

Database of Orthologous Groups

More...OrthoDBi		1060706at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.1610.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR025574, Nucleoporin_FG_rpt
IPR037665, Nucleoporin_S59-like
IPR037637, NUP98-NUP96
IPR007230, Peptidase_S59
IPR036903, Peptidase_S59_sf

The PANTHER Classification System

More...PANTHERi		PTHR23198, PTHR23198, 2 hits
PTHR23198:SF17, PTHR23198:SF17, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF04096, Nucleoporin2, 1 hit
PF13634, Nucleoporin_FG, 7 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF82215, SSF82215, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51434, NUP_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G8C1A6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFGSTSNTFG GTNKPFGAPA ATNAPSPFGT TQPNNNASPF GMNNAPTQIT 
        60         70         80         90        100
SSFGSNLGSS FGNTAGATFG SNPFNSANSS GNNANTMFGM NNNTAGVNAN 
       110        120        130        140        150
NNNPANASSP FGQTNNTGGM LFGNNPLTAG STNSSAGGNL GTGIKPFMES 
       160        170        180        190        200
QEKDNTTGTM NHFQSITCMP EYRNYSFEEL RFQDYQANRK FSNNPGSSGS 
       210        220        230        240        250
QFSNTAANNA FGTGINSTQP TNTSNLFGQN NMAQNSMFGS ANSNNAFGSN 
       260        270        280        290        300
FGTNTSSQFG ANKPASGGLF GQTNTNNQPS GGLFGQSNSQ PSGGLFGQNN 
       310        320        330        340        350
TTQPSGGLFG QSNTTQPSGG LFGQSNTNQP QSSGLFGQSN TTQQPSGGLF 
       360        370        380        390        400
GAAQPSSAGG LFGQNNNTFG QNNNSQQPGG LFGQNNNNTN QQSGGLFGQN 
       410        420        430        440        450
NNQQQAGGIF GAKPAATTGG LFGQANNAFG QNNNTQQTGG LFGQANTNNQ 
       460        470        480        490        500
SSGGLFGQNN NSQPSGGLFG QSNTTQPSGG LFGQSNTNQP QSSGLFGQSN 
       510        520        530        540        550
TAQQPSGGLF GNKPAAPAGG LFGSKPMAPS GGLFGQSNNA QQTSGGLFGQ 
       560        570        580        590        600
NNTQQQSGGL FGAKPAAPAG GLFGNKPATT SAGSLFGNNA NATNSTNTTT 
       610        620        630        640        650
GGLFGNATAN NTPNTLGGGL FGNKTQTPAA PVGGLFGQSN GTGGNVSSGL 
       660        670        680        690        700
FGNKSAMNAG GASAGGLFGN NNVSTLGNTL GNNNQQNSQQ QQYQQLQQNI 
       710        720        730        740        750
ANQNPYGTQE LFSRITMPPS ITEPEKATVT VADTGKNSSF NKAKTSVKSQ 
       760        770        780        790        800
PLFHRHSTVP QPVALSRIHG PVASSLNKTY STALVSTKNP AANELDKAIK 
       810        820        830        840        850
GVESLIHNPH SVSFKTLVIN KKKQEDIEDS NTDIGIISLG KSSSDTDKDS 
       860        870        880        890        900
VTSSESIFDR AQETPTVKDT TRISSSNLDT MSTLSTTSPM PSQITQVKVE 
       910        920        930        940        950
DELNLDDISY VDDNYFISPS LETLSGYSLI KLRKVSNLVI GHKKYGKVKF 
       960        970        980        990       1000
LEPVDLSGIP LGLLCGEIVR FSPRTCSVEI KDDPNGSLTK GMNVRAKVTL 
      1010       1020       1030       1040       1050
YSCFPIDKAT KMPITDGNHE MVKRQIHKFK QVPGSKLESY DTDSGTLVFS 

VNEVCA
Length:1,056
Mass (Da):109,058
Last modified:January 25, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i60E95D6D6B5C3A83
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
HE612869 Genomic DNA Translation: CCE65934.1

NCBI Reference Sequences

More...RefSeqi		XP_003688368.1, XM_003688320.1

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		CCE65934; CCE65934; TPHA_0N01530

Database of genes from NCBI RefSeq genomes

More...GeneIDi		11532122

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		tpf:TPHA_0N01530

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE612869 Genomic DNA Translation: CCE65934.1
RefSeqiXP_003688368.1, XM_003688320.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi113608.XP_003688368.1

Genome annotation databases

EnsemblFungiiCCE65934; CCE65934; TPHA_0N01530
GeneIDi11532122
KEGGitpf:TPHA_0N01530

Phylogenomic databases

eggNOGiKOG0845, Eukaryota
HOGENOMiCLU_011051_0_0_1
OrthoDBi1060706at2759

Family and domain databases

Gene3Di3.30.1610.10, 1 hit
InterProiView protein in InterPro
IPR025574, Nucleoporin_FG_rpt
IPR037665, Nucleoporin_S59-like
IPR037637, NUP98-NUP96
IPR007230, Peptidase_S59
IPR036903, Peptidase_S59_sf
PANTHERiPTHR23198, PTHR23198, 2 hits
PTHR23198:SF17, PTHR23198:SF17, 2 hits
PfamiView protein in Pfam
PF04096, Nucleoporin2, 1 hit
PF13634, Nucleoporin_FG, 7 hits
SUPFAMiSSF82215, SSF82215, 1 hit
PROSITEiView protein in PROSITE
PS51434, NUP_C, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG8C1A6_TETPH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G8C1A6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: February 10, 2021
This is version 41 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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