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Entry version 32 (11 Dec 2019)
Sequence version 1 (25 Jan 2012)
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Protein

Transmembrane 9 superfamily member

Gene

TPHA0K00730

Organism
Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Protein family/group databases

Transport Classification Database

More...
TCDBi
8.A.68.1.11 the endomembrane protein-70 (emp70) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane 9 superfamily memberUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TPHA0K00730Imported
Ordered Locus Names:TPHA_0K00730Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1071381 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeTetrapisispora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005666 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei7 – 25HelicalUniRule annotationAdd BLAST19
Transmembranei302 – 324HelicalUniRule annotationAdd BLAST23
Transmembranei357 – 380HelicalUniRule annotationAdd BLAST24
Transmembranei392 – 415HelicalUniRule annotationAdd BLAST24
Transmembranei435 – 458HelicalUniRule annotationAdd BLAST24
Transmembranei470 – 492HelicalUniRule annotationAdd BLAST23
Transmembranei560 – 578HelicalUniRule annotationAdd BLAST19
Transmembranei620 – 640HelicalUniRule annotationAdd BLAST21
Transmembranei661 – 678HelicalUniRule annotationAdd BLAST18
Transmembranei698 – 720HelicalUniRule annotationAdd BLAST23

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
113608.XP_003687641.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG1278 Eukaryota
ENOG410XPIW LUCA

KEGG Orthology (KO)

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KOi
K17086

Database of Orthologous Groups

More...
OrthoDBi
641127at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004240 EMP70

The PANTHER Classification System

More...
PANTHERi
PTHR10766 PTHR10766, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02990 EMP70, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G8BZ79-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLFEKRLWF VPIICVAYLF ILFSFSCKSL TTVPRTTYGK QSKGWVHPNT
60 70 80 90 100
YTFGDPVEVI VNKMVQEKDM LGDSNEGVSY KYHDLPYICP PTNTKKSIHN
110 120 130 140 150
SLKELFNGDY NEQSDYILKF GVDNDCQALC LRKTYNAGIR KAKEMIDEDY
160 170 180 190 200
IVNWFIDDYL PAATTYISSV TRKKKYFEGF SLGWKDPETG SYYINNHVML
210 220 230 240 250
VIRYNAVDDN KFNIVGFEVY PKSIPDLQCP GARRGHGHYE LKDLENNDEF
260 270 280 290 300
SLIPFSYSVY WREEFEYDWR TRWSLFVRPN YMDLDAEDES LQLGFISNLL
310 320 330 340 350
HWYSPYTTVI IFTILLFLVS LLVLDINSHK LVFMSNPKTV IAWATTANKL
360 370 380 390 400
NKTWKNILLN ILVSMGCQAL FIFMPVIVIQ SSLWSLHNIS NYVMLQIICW
410 420 430 440 450
ISASLLVGSF VGTWLRMYMF QKKMTPNYDP KMSIVCGSIL PGLTLAGVTV
460 470 480 490 500
FNTVTWFLEG NSSYPFRKLS WLIFVYFIFS IPMSLIGGSL AVKIQHYYTN
510 520 530 540 550
FSSRKDYGRV RSMSYTDPNL YKPDIIESDI QKNQDNEDNY VIELDDKQAK
560 570 580 590 600
KRKIWRRKSL YVKFKQAISF SNIISLLLRN FITNGIPFQI IKNEVIIFNQ
610 620 630 640 650
SSWLRHCSFF NLFGYLFTKY IMIIAIIFMG SVISCNLYLI QSTSDKGSNI
660 670 680 690 700
KENWRGKCFQ LGFNLFFAME FNSLSHILNR SNEKWGTLLL LSIGYSLLFN
710 720 730
LLIGLAAGFI SYMASVWFIV NRFKSQGPVH LYD
Length:733
Mass (Da):85,255
Last modified:January 25, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8876FC6E0DA95EFA
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
HE612866 Genomic DNA Translation: CCE65207.1

NCBI Reference Sequences

More...
RefSeqi
XP_003687641.1, XM_003687593.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
CCE65207; CCE65207; TPHA_0K00730

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
11533379

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
tpf:TPHA_0K00730

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE612866 Genomic DNA Translation: CCE65207.1
RefSeqiXP_003687641.1, XM_003687593.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi113608.XP_003687641.1

Protein family/group databases

TCDBi8.A.68.1.11 the endomembrane protein-70 (emp70) family

Genome annotation databases

EnsemblFungiiCCE65207; CCE65207; TPHA_0K00730
GeneIDi11533379
KEGGitpf:TPHA_0K00730

Phylogenomic databases

eggNOGiKOG1278 Eukaryota
ENOG410XPIW LUCA
KOiK17086
OrthoDBi641127at2759

Family and domain databases

InterProiView protein in InterPro
IPR004240 EMP70
PANTHERiPTHR10766 PTHR10766, 1 hit
PfamiView protein in Pfam
PF02990 EMP70, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG8BZ79_TETPH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G8BZ79
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: December 11, 2019
This is version 32 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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