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UniProtKB - G7YQ16 (G7YQ16_CLOSI)

Entry version 19 (12 Aug 2020)
Sequence version 1 (25 Jan 2012)
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Protein
Submitted name:

Ribose 5-phosphate isomerase A

Gene

CLF_106564

Organism
Clonorchis sinensis (Chinese liver fluke)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIsomeraseImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ribose 5-phosphate isomerase AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CLF_106564Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiClonorchis sinensis (Chinese liver fluke)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri79923 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Spiralia › Lophotrochozoa › Platyhelminthes › Trematoda › Digenea › Opisthorchiida › Opisthorchiata › Opisthorchiidae › Clonorchis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008909 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Integrator subunit 2 family.ARBA annotation

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		G7YQ16

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR026236, Int2_metazoa
IPR029321, INTS2

The PANTHER Classification System

More...PANTHERi		PTHR28608, PTHR28608, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14750, INTS2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR02105, INTSUBUNIT2

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G7YQ16-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQHCIRYVSL SNPRNFCPGI PDFPILPAFV CGYISHANRT NFHLLKRLFR 
        60         70         80         90        100
NIPFEWFTVW NWLIRLSEQL SLGVTVPEIL HSCGTSSSSN EPGFLFSLST 
       110        120        130        140        150
ELDRNLLLHR IEGTIRSLLL VCPNYTRMVI ERCLSIHCFP GLVVDALFFL 
       160        170        180        190        200
DKSDDNSLLI YLKRMLLDSG TRTRSWISAY LKRQMGADGQ LEKFSQYFIR 
       210        220        230        240        250
SSASLIPSDP SIPLTNDVIL KALLLLRVLA AMRGFVNYIF PPTLSSQLLT 
       260        270        280        290        300
LLTHKTVDSE RGSQYITYSL AFLIGLRSSL QVPQDVIVRT GSSSDIESQI 
       310        320        330        340        350
VVWLQGLINR QTHVPPAGLS DEQHSILLNT PNNRPYTETL LLLAILFHTN 
       360        370        380        390        400
QPGPITDLIS NLLGLRIPSL GRTVNGWRKI FLQSVFTESM IASQVARVPI 
       410        420        430        440        450
TPLLNRSLST HLPIQCALQL LKSHAFAKNK LEIKDWLVGQ VRQSVRPMHP 
       460        470        480        490        500
LLPDLVEAHI VHSFGASSTP GCISDPSALI SERELIAQIQ NGAKYPLAQL 
       510        520        530        540        550
CSPSLDMACK DSTPPTDSTQ VDFTAELLFL YYALYVYDYQ ITSRLLSNRH 
       560        570        580        590        600
CLPGEAPCFY SDQLWDCIPI TYLLRHARSN VTDYGPLYPR LLQLVTNHFP 
       610        620        630        640        650
NLTVGELMIQ DELLLDPIWC PQVKRFSAPA QQSVQYELTI DSAQLHCATN 
       660        670        680        690        700
TVNICSPTEL DEAFEAVLTH ITPFCESGDD QRPSQANLAR TSVHHLIRLI 
       710        720        730        740        750
QRLSQAVEQL SVDCLLPFGP VLGHQCPRLL LAANKHPLFT TNRRFVCRLE 
       760        770        780        790        800
YLWCRLHLVM PRKLELLTVN ALIDGVNSKK PSCSSLRCIR SVKKLTGADI 
       810        820        830        840        850
RIDPVENLMN TVDRGVFRCP PVLRMFLRIL ESNLLASRSY WGHRLLERVV 
       860        870        880        890        900
NPPASTSVPF GSVTNTVTLP SVQSGNTSES ALDSSLPSLP TTTSVVNATA 
       910        920        930        940        950
SARTIAPVSD EECEVLCSNM LLTQNATVVQ LLLEHCLPTK EESTLRSKIS 
       960        970        980        990       1000
VLREVQNIIC TYVHSMFIAE PALAEVIVWQ TFPNSLLPIS TQAIPSLHIC 
      1010       1020       1030       1040       1050
LDSVIHVYRL SGDYAKMVFC LDLVSHLSLH YNIQSAFERA AFMIDSLFHL 
      1060       1070       1080       1090       1100
LSSVVCADDR PDLLQACLPA FLRLGGAFPS LAPVIVRLLL TVGTLISSVL 
      1110       1120       1130       1140       1150
PDEARDSLRL RKSDEKRPEP ATWTAATYDL PLLDRSMLCL EHVMWTFDKL 
      1160 
IHRCSAQRYL YYPPELTC
Length:1,168
Mass (Da):130,942
Last modified:January 25, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i886FBB429FE56FBB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
DF143956 Genomic DNA Translation: GAA55047.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DF143956 Genomic DNA Translation: GAA55047.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Phylogenomic databases

InParanoidiG7YQ16

Family and domain databases

InterProiView protein in InterPro
IPR026236, Int2_metazoa
IPR029321, INTS2
PANTHERiPTHR28608, PTHR28608, 1 hit
PfamiView protein in Pfam
PF14750, INTS2, 1 hit
PRINTSiPR02105, INTSUBUNIT2

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG7YQ16_CLOSI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G7YQ16
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: August 12, 2020
This is version 19 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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