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Entry version 19 (12 Aug 2020)
Sequence version 1 (25 Jan 2012)
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Protein
Submitted name:

Ribose 5-phosphate isomerase A

Gene

CLF_106564

Organism
Clonorchis sinensis (Chinese liver fluke)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIsomeraseImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ribose 5-phosphate isomerase AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CLF_106564Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiClonorchis sinensis (Chinese liver fluke)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri79923 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaSpiraliaLophotrochozoaPlatyhelminthesTrematodaDigeneaOpisthorchiidaOpisthorchiataOpisthorchiidaeClonorchis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008909 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Integrator subunit 2 family.ARBA annotation

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
G7YQ16

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR026236, Int2_metazoa
IPR029321, INTS2

The PANTHER Classification System

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PANTHERi
PTHR28608, PTHR28608, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14750, INTS2, 1 hit

Protein Motif fingerprint database; a protein domain database

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PRINTSi
PR02105, INTSUBUNIT2

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

G7YQ16-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQHCIRYVSL SNPRNFCPGI PDFPILPAFV CGYISHANRT NFHLLKRLFR
60 70 80 90 100
NIPFEWFTVW NWLIRLSEQL SLGVTVPEIL HSCGTSSSSN EPGFLFSLST
110 120 130 140 150
ELDRNLLLHR IEGTIRSLLL VCPNYTRMVI ERCLSIHCFP GLVVDALFFL
160 170 180 190 200
DKSDDNSLLI YLKRMLLDSG TRTRSWISAY LKRQMGADGQ LEKFSQYFIR
210 220 230 240 250
SSASLIPSDP SIPLTNDVIL KALLLLRVLA AMRGFVNYIF PPTLSSQLLT
260 270 280 290 300
LLTHKTVDSE RGSQYITYSL AFLIGLRSSL QVPQDVIVRT GSSSDIESQI
310 320 330 340 350
VVWLQGLINR QTHVPPAGLS DEQHSILLNT PNNRPYTETL LLLAILFHTN
360 370 380 390 400
QPGPITDLIS NLLGLRIPSL GRTVNGWRKI FLQSVFTESM IASQVARVPI
410 420 430 440 450
TPLLNRSLST HLPIQCALQL LKSHAFAKNK LEIKDWLVGQ VRQSVRPMHP
460 470 480 490 500
LLPDLVEAHI VHSFGASSTP GCISDPSALI SERELIAQIQ NGAKYPLAQL
510 520 530 540 550
CSPSLDMACK DSTPPTDSTQ VDFTAELLFL YYALYVYDYQ ITSRLLSNRH
560 570 580 590 600
CLPGEAPCFY SDQLWDCIPI TYLLRHARSN VTDYGPLYPR LLQLVTNHFP
610 620 630 640 650
NLTVGELMIQ DELLLDPIWC PQVKRFSAPA QQSVQYELTI DSAQLHCATN
660 670 680 690 700
TVNICSPTEL DEAFEAVLTH ITPFCESGDD QRPSQANLAR TSVHHLIRLI
710 720 730 740 750
QRLSQAVEQL SVDCLLPFGP VLGHQCPRLL LAANKHPLFT TNRRFVCRLE
760 770 780 790 800
YLWCRLHLVM PRKLELLTVN ALIDGVNSKK PSCSSLRCIR SVKKLTGADI
810 820 830 840 850
RIDPVENLMN TVDRGVFRCP PVLRMFLRIL ESNLLASRSY WGHRLLERVV
860 870 880 890 900
NPPASTSVPF GSVTNTVTLP SVQSGNTSES ALDSSLPSLP TTTSVVNATA
910 920 930 940 950
SARTIAPVSD EECEVLCSNM LLTQNATVVQ LLLEHCLPTK EESTLRSKIS
960 970 980 990 1000
VLREVQNIIC TYVHSMFIAE PALAEVIVWQ TFPNSLLPIS TQAIPSLHIC
1010 1020 1030 1040 1050
LDSVIHVYRL SGDYAKMVFC LDLVSHLSLH YNIQSAFERA AFMIDSLFHL
1060 1070 1080 1090 1100
LSSVVCADDR PDLLQACLPA FLRLGGAFPS LAPVIVRLLL TVGTLISSVL
1110 1120 1130 1140 1150
PDEARDSLRL RKSDEKRPEP ATWTAATYDL PLLDRSMLCL EHVMWTFDKL
1160
IHRCSAQRYL YYPPELTC
Length:1,168
Mass (Da):130,942
Last modified:January 25, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i886FBB429FE56FBB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DF143956 Genomic DNA Translation: GAA55047.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DF143956 Genomic DNA Translation: GAA55047.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Phylogenomic databases

InParanoidiG7YQ16

Family and domain databases

InterProiView protein in InterPro
IPR026236, Int2_metazoa
IPR029321, INTS2
PANTHERiPTHR28608, PTHR28608, 1 hit
PfamiView protein in Pfam
PF14750, INTS2, 1 hit
PRINTSiPR02105, INTSUBUNIT2

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiG7YQ16_CLOSI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: G7YQ16
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 25, 2012
Last sequence update: January 25, 2012
Last modified: August 12, 2020
This is version 19 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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